Esophagitis causes

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Ajay Gade MD [2]]

Overview

Common causes of esophagitis include gastroesophageal reflux disease, Barrett's esophagus, caustic burns, and chemical injury by either alkaline or acid solutions. Among immunocompromised patients, the most common causes of esophagitis are Candidiasis, Cytomegalovirus, and Herpes simplex virus

Causes

Common Causes

Common causes of esophagitis include:^[1]^[2]^[3]^[4]^[5]^[6]^[7]^[8]

Barrett's esophagus
Candidiasis in immunocompromised patients
Caustic burn
Chemical injury by alkaline or acid solutions
Cytomegalovirus in immunocompromised patients
Gastroesophageal reflux disease
Herpes simplex virus in immunocompromised patients
Radiation therapy

Causes by Organ System

Cardiovascular	No underlying causes
Chemical/Poisoning	Caustic burn, Chemical esophagitis, Chemical injury, Formaldehyde, Toxins
Dental	No underlying causes
Dermatologic	Lichen planus, Scleroderma
Drug Side Effect	Alendronate, Alprenolol, Amlodipine and Benazepril, Ascorbic acid, Bisphosphonate, Caffeine, Cidofovir, Clindamycin, Dactinomycin, Doxorubicin Hydrochloride, Doxycycline, Emepronium, Etidronate, ethanolamine oleate, Felbamate, Ferrous sulfate, ibandronate, iron compounds, Ixabepilone, Leflunomide, Mycophenolic acid, Pergolide, Oxaprozin, Oxcarbazepine, Oxytetracycline, Pinaverium , Potassium chloride, Pramipexole, Quinidine, Rauwolfia, Risedronate, Sertraline, Tetracycline
Ear Nose Throat	No underlying causes
Endocrine	No underlying causes
Environmental	No underlying causes
Gastroenterologic	Barrett's esophagus, Candidiasis, Chemical esophagitis, Crohn's Disease, Dyspepsia, Eosinophilic esophagitis, Eosinophilic gastroenteritis, Esophageal achalasia, Esophageal food bolus obstruction, Esophageal stricture, Esophageal varices, Gastroesophageal reflux disease, Gastroscopy, Hernias, Hiatus hernia, Impaired esophageal motility, inflammatory bowel disease, Nasogastric tube, Reflux esophagitis, Rumination disorder, Upper gastrointestinal bleeding
Genetic	No underlying causes
Hematologic	No underlying causes
Iatrogenic	Gastric tube, Gastroscopy, Nasogastric tube, Radiation therapy
Infectious Disease	Acquired Immune Deficiency Syndrome, Candidiasis, Cytomegalovirus, Fungal infection, Herpes simplex, HSV-1, Varicella zoster virus
Musculoskeletal/Orthopedic	No underlying causes
Neurologic	No underlying causes
Nutritional/Metabolic	No underlying causes
Obstetric/Gynecologic	No underlying causes
Oncologic	Tumor
Ophthalmologic	No underlying causes
Overdose/Toxicity	No underlying causes
Psychiatric	No underlying causes
Pulmonary	No underlying causes
Renal/Electrolyte	No underlying causes
Rheumatology/Immunology/Allergy	Acquired Immune Deficiency Syndrome, Behcet disease, Candidiasis, Crohn's Disease, Cytomegalovirus, Eosinophilic esophagitis, Eosinophilic gastroenteritis, Food allergy, Graft versus host disease, inflammatory bowel disease, Lichen planus, Scleroderma
Sexual	No underlying causes
Trauma	No underlying causes
Urologic	No underlying causes
Miscellaneous	Esophageal achalasia, Esophageal food bolus obstruction, Esophageal stricture, Esophageal varices, Food allergy, Foreign bodies, Gastric tube, Impaired esophageal motility, Lichen planus, Physical injury, Rumination disorder

Casues in Alphabetical Order

References

↑ Makar AB, McMartin KE, Palese M, Tephly TR, Kia L, Hirano I (1975). "Formate assay in body fluids: application in methanol poisoning". Biochem Med. 13 (2): 117–26. doi:10.1038/nrgastro.2015.75. PMC 4948861. PMID 1.
↑ Savarino EV, Tolone S, Bartolo O, de Cassan C, Caccaro R, Galeazzi F, Nicoletti L, Salvador R, Martinato M, Costantini M, Savarino V (2016). "The GerdQ questionnaire and high resolution manometry support the hypothesis that proton pump inhibitor-responsive oesophageal eosinophilia is a GERD-related phenomenon". Aliment. Pharmacol. Ther. 44 (5): 522–30. doi:10.1111/apt.13718. PMID 27373195.
↑ Straumann A (2013). "Eosinophilic esophagitis: a bulk of mysteries". Dig Dis. 31 (1): 6–9. doi:10.1159/000347095. PMID 23797116.
↑ Straumann A (2012). "Eosinophilic esophagitis: rapidly emerging disorder". Swiss Med Wkly. 142: w13513. doi:10.4414/smw.2012.13513. PMID 22307811.
↑ Schoepfer AM, Simon D, Straumann A (2011). "Eosinophilic oesophagitis: latest intelligence". Clin. Exp. Allergy. 41 (5): 630–9. doi:10.1111/j.1365-2222.2011.03739.x. PMID 21429051.
↑ Godat S, Moradpour D, Schoepfer A (2011). "[Eosinophilic esophagitis: update 2011]". Rev Med Suisse (in French). 7 (307): 1678–80, 1682. PMID 21987875.
↑ Potter JW, Saeian K, Staff D, Massey BT, Komorowski RA, Shaker R, Hogan WJ (2004). "Eosinophilic esophagitis in adults: an emerging problem with unique esophageal features". Gastrointest. Endosc. 59 (3): 355–61. PMID 14997131.
↑ Ayazi S, Crookes P, Peyre C, (2007). "Objective documentation of the link between gastroesophageal reflux disease and obesity". Am. J. Gastroenterol. 102 (S): 138–139.

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[pmid1-1] Makar AB, McMartin KE, Palese M, Tephly TR, Kia L, Hirano I (1975). "Formate assay in body fluids: application in methanol poisoning". Biochem Med. 13 (2): 117–26. doi:10.1038/nrgastro.2015.75. PMC 4948861. PMID 1.

[pmid27373195-2] Savarino EV, Tolone S, Bartolo O, de Cassan C, Caccaro R, Galeazzi F, Nicoletti L, Salvador R, Martinato M, Costantini M, Savarino V (2016). "The GerdQ questionnaire and high resolution manometry support the hypothesis that proton pump inhibitor-responsive oesophageal eosinophilia is a GERD-related phenomenon". Aliment. Pharmacol. Ther. 44 (5): 522–30. doi:10.1111/apt.13718. PMID 27373195.

[pmid23797116-3] Straumann A (2013). "Eosinophilic esophagitis: a bulk of mysteries". Dig Dis. 31 (1): 6–9. doi:10.1159/000347095. PMID 23797116.

[pmid22307811-4] Straumann A (2012). "Eosinophilic esophagitis: rapidly emerging disorder". Swiss Med Wkly. 142: w13513. doi:10.4414/smw.2012.13513. PMID 22307811.

[pmid21429051-5] Schoepfer AM, Simon D, Straumann A (2011). "Eosinophilic oesophagitis: latest intelligence". Clin. Exp. Allergy. 41 (5): 630–9. doi:10.1111/j.1365-2222.2011.03739.x. PMID 21429051.

[pmid21987875-6] Godat S, Moradpour D, Schoepfer A (2011). "[Eosinophilic esophagitis: update 2011]". Rev Med Suisse (in French). 7 (307): 1678–80, 1682. PMID 21987875.

[pmid14997131-7] Potter JW, Saeian K, Staff D, Massey BT, Komorowski RA, Shaker R, Hogan WJ (2004). "Eosinophilic esophagitis in adults: an emerging problem with unique esophageal features". Gastrointest. Endosc. 59 (3): 355–61. PMID 14997131.

[pmid175737910-8] Ayazi S, Crookes P, Peyre C, (2007). "Objective documentation of the link between gastroesophageal reflux disease and obesity". Am. J. Gastroenterol. 102 (S): 138–139.

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