Exocyst complex component 6b

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Identifiers
Aliases
External IDs	GeneCards: [1]
Orthologs
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a
Wikidata
View/Edit Human

Exocyst complex component 6B is a protein that in humans is encoded by the EXOC6B gene.

Function

In yeast and rat, Sec15 is part of a multiprotein complex that is required for targeted exocytosis.

Further reading

• Brymora A, Valova VA, Larsen MR, Roufogalis BD, Robinson PJ (August 2001). "The brain exocyst complex interacts with RalA in a GTP-dependent manner: identification of a novel mammalian Sec3 gene and a second Sec15 gene". The Journal of Biological Chemistry. 276 (32): 29792–7. doi:10.1074/jbc.C100320200. PMID 11406615.
• Feng S, Knödler A, Ren J, Zhang J, Zhang X, Hong Y, Huang S, Peränen J, Guo W (May 2012). "A Rab8 guanine nucleotide exchange factor-effector interaction network regulates primary ciliogenesis". The Journal of Biological Chemistry. 287 (19): 15602–9. doi:10.1074/jbc.M111.333245. PMC 3346093. PMID 22433857.
• Wen J, Lopes F, Soares G, Farrell SA, Nelson C, Qiao Y, Martell S, Badukke C, Bessa C, Ylstra B, Lewis S, Isoherranen N, Maciel P, Rajcan-Separovic E (July 2013). "Phenotypic and functional consequences of haploinsufficiency of genes from exocyst and retinoic acid pathway due to a recurrent microdeletion of 2p13.2". Orphanet Journal of Rare Diseases. 8: 100. doi:10.1186/1750-1172-8-100. PMC 3710273. PMID 23837398.
• Borsani G, Piovani G, Zoppi N, Bertini V, Bini R, Notarangelo L, Barlati S (2008). "Cytogenetic and molecular characterization of a de-novo t(2p;7p) translocation involving TNS3 and EXOC6B genes in a boy with a complex syndromic phenotype". European Journal of Medical Genetics. 51 (4): 292–302. doi:10.1016/j.ejmg.2008.02.006. PMID 18424204.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.