Fibromyalgia history and symptoms

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

The defining symptoms of fibromyalgia are chronic, widespread pain and tenderness to light touch.

History and Symptoms

The defining symptoms of fibromyalgia are chronic, widespread pain and tenderness to light touch. Other symptoms include:[1][2][3][4][5][6][7]

Organ system Symptoms
Systemic
CNS
Musculoskeletal
Abdominal
Eyes

The following factors have been proposed to exacerbate symptoms of pain in patients with fibromyalgia:

  • Increased psychosocial stress
  • Excessive physical exertion (exercise seems to decrease the pain threshold of people with fibromyalgia but increase the pain threshold in healthy individuals)[8]
  • Lack of slow-wave sleep
  • Changes in humidity and barometric pressure (see RSD, CRPS, and thermography)

References

  1. Leavitt F, Katz RS, Mills M, Heard AR (2002). "Cognitive and Dissociative Manifestations in Fibromyalgia". J Clin Rheumatol. 8 (2): 77–84. PMID 17041327.
  2. Frank Leavitt. "Fibrofog, Fibromyalgia and Dissociation -- Understanding why some memory-impaired patients with fibromyalgia score normally on neuropsychological testing".
  3. Musculosketal symptoms and non-REM sleep disturban...[Psychosom Med. 1975 Jul-Aug] - PubMed Result
  4. Fibromyalgia: the gastrointestinal link. [Curr Pain Headache Rep. 2004] - PubMed Result
  5. Cognitive dysfunction in fibromyalgia and chronic ...[Curr Rheumatol Rep. 2006] - PubMed Result
  6. Comorbidity of fibromyalgia and psychiatric disord...[Curr Pain Headache Rep. 2007] - PubMed Result
  7. Tander B, Atmaca A, Aliyazicioglu Y, Canturk F (2007). "Serum ghrelin levels but not GH, IGF-1 and IGFBP-3 levels are altered in patients with fibromyalgia syndrome". Joint Bone Spine. 74 (5): 477–81. doi:10.1016/j.jbspin.2007.01.024. PMID 17689128.
  8. Staud R, Robinson ME, Price DD (2005). "Isometric exercise has opposite effects on central pain mechanisms in fibromyalgia patients compared to normal controls". Pain. 118 (1–2): 176–84. PMID 16154700.