Filariasis historical perspective
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Ahmed Elsaiey, MBBCH [2]
Overview
Jan Huygen Linschoten discovered filariasis in the 16th century after his trip to Goa. In the 19th century there were many discoveries regarding filariasis, the infective worms, and the arthropod vectors. In 1866, microfilariae were detected in urine and blood. Ten years later in 1876, Joseph Bancroft discovered the adult worm which is responsible for the infection and named it as "Wuchereria bancrofti". More discoveries and description of the life cycles of the worms were made in the 1900s.
Historical Perspective
- In the 16th century, Jan Huygen Linschoten discovered filariasis during his trip to Goa. After that, more reports of the disease came out from Asia and Africa.[1]
- In 1866, Timothy Lewis continued what Jean-Nicolas Demarquay and Otto Henry Wucherer started 3 years before him when they detected microfilariae in hydrocele. Timothy made a connection between these microfilariae and the elephantiasis when he discovered the presence of the microfilariae in the blood and urine.
- In 1876, Joseph Bancroft discovered the adult round worm which is responsible for filariasis and was named Wuchereria bancrofti .
- In 1877, Patricj Manson described the life cycle of the arthropod vector causing the disease when he discovered the microfilariae in the mosquitoes. It was also the discovery of arthropod to be the vector.
- In 1900, George Carmichael described how the disease is transmitted when he discovered the presence of the worm in the mosquito vector.
- In 1915. Dr. Rodolfo Robles Valverde conducted a study on patients with river blindness in Guatemala which led to the discovery of O. volvulus as the filaria causing the disease.
References
- ↑ Chandy A, Thakur AS, Singh MP, Manigauha A (2011). "A review of neglected tropical diseases: filariasis". Asian Pac J Trop Med. 4 (7): 581–6. doi:10.1016/S1995-7645(11)60150-8. PMID 21803313.