Folate deficiency physical examination

	Folate deficiency Microchapters
Home
Patient Information
Overview
Historical Perspective
Classification
Pathophysiology
Causes
Differentiating Folate deficiency from other Diseases
Epidemiology and Demographics
Risk Factors
Screening
Natural History, Complications and Prognosis
Diagnosis
Diagnostic Study of Choice
History and Symptoms
Physical Examination
Laboratory Findings
Electrocardiogram
X ray
Echocardiography and Ultrasound
CT Scan
MRI
Other Imaging Findings
Other Diagnostic Studies
Treatment
Medical Therapy
Surgery
Primary Prevention
Secondary Prevention
Cost-Effectiveness of Therapy
Future or Investigational Therapies
Case Studies
Case #1
Folate deficiency physical examination On the Web
Most recent articles
Most cited articles
Review articles
CME Programs
Powerpoint slides
Images
American Roentgen Ray Society Images of Folate deficiency physical examination All Images X-rays Echo & Ultrasound CT Images MRI
Ongoing Trials at Clinical Trials.gov
US National Guidelines Clearinghouse
NICE Guidance
FDA on Folate deficiency physical examination
CDC on Folate deficiency physical examination
Folate deficiency physical examination in the news
Blogs on Folate deficiency physical examination
Directions to Hospitals Treating Folate deficiency
Risk calculators and risk factors for Folate deficiency physical examination

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Patients with folate deficiency may appear normal in some cases but usually if anemia is moderate or severe, the patient would appear pale,malnourished or underdeveloped. All organ systems can be involved by the effects of anemia.

Physical Examination

Appearance of the patient

Patients with folate deficiency anemia may appear pale, malnourished or underdeveloped.

Vital signs

Tachycardia

HEENT

Pallor
Jaundice^[1]
Angular stomatitis
Cheilosis
Glossitis

Skin

Pale skin color (pallor)
Hyperpigmentation

Lungs

Tachypnea
Dyspnea

Heart

Tachycardia
Systolic flow murmur

Neuromuscular

Slowly progressive sensory neuropathy, predominantly deep sensory loss, with preservation of bicep tendon reflexes^[2]
Neurological deficits or Neural tube defects in neonates

References

↑ Green R, Datta Mitra A (2017). "Megaloblastic Anemias: Nutritional and Other Causes". Med Clin North Am. 101 (2): 297–317. doi:10.1016/j.mcna.2016.09.013. PMID 28189172.
↑ Koike H, Takahashi M, Ohyama K, Hashimoto R, Kawagashira Y, Iijima M; et al. (2015). "Clinicopathologic features of folate-deficiency neuropathy". Neurology. 84 (10): 1026–33. doi:10.1212/WNL.0000000000001343. PMID 25663227.

Template:WS Template:WH

[pmid28189172-1] Green R, Datta Mitra A (2017). "Megaloblastic Anemias: Nutritional and Other Causes". Med Clin North Am. 101 (2): 297–317. doi:10.1016/j.mcna.2016.09.013. PMID 28189172.

[pmid25663227-2] Koike H, Takahashi M, Ohyama K, Hashimoto R, Kawagashira Y, Iijima M; et al. (2015). "Clinicopathologic features of folate-deficiency neuropathy". Neurology. 84 (10): 1026–33. doi:10.1212/WNL.0000000000001343. PMID 25663227.

[1]

[2]