GTPase IMAP family member 4 is an enzyme that in humans is encoded by the GIMAP4gene.[1][2][3]
This gene encodes a protein belonging to the GTP-binding superfamily and to the immuno-associated nucleotide (IAN) subfamily of nucleotide-binding proteins. The encoded protein of this gene may be negatively regulated by T-cell acute lymphocytic leukemia 1 (TAL1). In humans, the IAN subfamily genes are located in a cluster at 7q36.1.[3]
References
↑Krucken J, Schroetel RM, Muller IU, Saidani N, Marinovski P, Benten WP, Stamm O, Wunderlich F (Oct 2004). "Comparative analysis of the human gimap gene cluster encoding a novel GTPase family". Gene. 341: 291–304. doi:10.1016/j.gene.2004.07.005. PMID15474311.
Dominguez O, Ashhab Y, Sabater L, et al. (1999). "Cloning of ARE-containing genes by AU-motif-directed display". Genomics. 54 (2): 278–86. doi:10.1006/geno.1998.5548. PMID9828130.
Stamm O, Krücken J, Schmitt-Wrede HP, et al. (2002). "Human ortholog to mouse gene imap38 encoding an ER-localizable G-protein belongs to a gene family clustered on chromosome 7q32-36". Gene. 282 (1–2): 159–67. doi:10.1016/S0378-1119(01)00837-X. PMID11814688.
Cambot M, Aresta S, Kahn-Perlès B, et al. (2002). "Human immune associated nucleotide 1: a member of a new guanosine triphosphatase family expressed in resting T and B cells". Blood. 99 (9): 3293–301. doi:10.1182/blood.V99.9.3293. PMID11964296.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID14702039.
