Gamma-glutamyltransferase 7 is an enzyme that in humans is encoded by the GGT7gene.[1][2][3]
Function
Gamma-glutamyltransferase is a membrane-associated protein involved in both the metabolism of glutathione and in the transpeptidation of amino acids. Changes in the activity of gamma-glutamyltransferase may signal preneoplastic or toxic conditions in the liver or kidney. The protein encoded by this gene is similar in sequence to gamma-glutamyltransferase, but its function is unknown.[3]
References
↑Figlewicz DA, Delattre O, Guellaen G, Krizus A, Thomas G, Zucman J, Rouleau GA (August 1993). "Mapping of human gamma-glutamyl transpeptidase genes on chromosome 22 and other human autosomes". Genomics. 17 (2): 299–305. doi:10.1006/geno.1993.1325. PMID8104871.
↑Heisterkamp N, Groffen J, Warburton D, Sneddon TP (May 2008). "The human gamma-glutamyltransferase gene family". Human Genetics. 123 (4): 321–32. doi:10.1007/s00439-008-0487-7. PMID18357469.
Jikuya H, Takano J, Kikuno R, Hirosawa M, Nagase T, Nomura N, Ohara O (February 2003). "Characterization of long cDNA clones from human adult spleen. II. The complete sequences of 81 cDNA clones". DNA Research. 10 (1): 49–57. doi:10.1093/dnares/10.1.49. PMID12693554.
Llamazares M, Cal S, Quesada V, López-Otín C (April 2003). "Identification and characterization of ADAMTS-20 defines a novel subfamily of metalloproteinases-disintegrins with multiple thrombospondin-1 repeats and a unique GON domain". The Journal of Biological Chemistry. 278 (15): 13382–9. doi:10.1074/jbc.M211900200. PMID12562771.
He X, Di Y, Li J, Xie Y, Tang Y, Zhang F, Wei L, Zhang Y, Qin W, Huo K, Li Y, Wan D, Gu J (September 2002). "Molecular cloning and characterization of CT120, a novel membrane-associated gene involved in amino acid transport and glutathione metabolism". Biochemical and Biophysical Research Communications. 297 (3): 528–36. doi:10.1016/S0006-291X(02)02227-1. PMID12270127.
