Glycogen storage disease type II electrocardiogram
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Anmol Pitliya, M.B.B.S. M.D.[2]
Overview
An ECG may be helpful in the diagnosis of glycogen storage disease type 2 (GSD type 2). Findings on an ECG suggestive of GSD type 2 include short PR interval, tall QRS, and left ventricular hypertrophy.
Electrocardiogram
- An ECG may be helpful in the diagnosis of glycogen storage disease type 2 (GSD type 2). Findings on an ECG suggestive of GSD type 2 include:[1][2][3]
- Short PR interval
- Tall QRS
- Left ventricular hypertrophy (large left ventricular (LV) voltages)
- Biventricular hypertrophy may also be seen
- Atrial hypertrophy is rare
- T-inversion
- ST-depression
- Increased QT dispersion
References
- ↑ van den Hout HM, Hop W, van Diggelen OP, Smeitink JA, Smit GP, Poll-The BT; et al. (2003). "The natural course of infantile Pompe's disease: 20 original cases compared with 133 cases from the literature". Pediatrics. 112 (2): 332–40. PMID 12897283.
- ↑ Ansong AK, Li JS, Nozik-Grayck E, Ing R, Kravitz RM, Idriss SF; et al. (2006). "Electrocardiographic response to enzyme replacement therapy for Pompe disease". Genet Med. 8 (5): 297–301. doi:10.109701.gim.0000195896.04069.5f Check
|doi=value (help). PMID 16702879. - ↑ ACMG Work Group on Management of Pompe Disease. Kishnani PS, Steiner RD, Bali D, Berger K, Byrne BJ; et al. (2006). "Pompe disease diagnosis and management guideline". Genet Med. 8 (5): 267–88. doi:10.109701.gim.0000218152.87434.f3 Check
|doi=value (help). PMC 3110959. PMID 16702877.