HLA-B54
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major histocompatibility complex (human), class I, B54
| ||
| Alleles | B*5401 | |
| Structure (See HLA-B) | ||
| Symbol(s) | HLA-B | |
| EBI-HLA | B*5401 | |
| Locus | chr.6 6p21.31 | |
HLA-B54 (B54) is an HLA-B serotype. B54 is a split antigen from the B22 broad antigen, sister serotypes are B55 and B56.[1] The serotype identifies the more common HLA-B*55 gene products.[2] (For terminology help see: HLA-serotype tutorial)
Serotype
| B*54 | B54 | B22 | Sample |
| allele | % | % | size (N) |
| 5401 | 67 | 3 | 631 |
Allele distribution
| freq | ||
| ref. | Population | (%) |
| [4] | USA Hawaii Okinawa | 10.6 |
| [4] | Japan Central | 7.7 |
| [4] | South Korea (3) | 5.9 |
| [4] | China Guangzhou | 4.5 |
| [4] | Thailand (3) | 4.1 |
| [4] | China Inner Mongolia | 3.4 |
| [4] | China North Han | 3.3 |
| [4] | China Beijing Shijiazhuang Tianjian Han | 3.0 |
| [4] | China South Han | 2.5 |
| [4] | Russia Tuva pop 2 | 2.2 |
| [4] | China Guangxi Maonan | 1.9 |
| [4] | Thailand | 1.8 |
| [4] | Taiwan Thao | 1.7 |
| [4] | China Tibet Autonomous Region Tibetans | 1.3 |
References
- ↑ Hildebrand WH, Madrigal JA, Little AM, Parham P (1992). "HLA-Bw22: a family of molecules with identity to HLA-B7 in the alpha 1-helix". J. Immunol. 148 (4): 1155–62. PMID 1737933.
- ↑ Marsh SG, Albert ED, Bodmer WF; et al. (2005). "Nomenclature for factors of the HLA system, 2004". Tissue Antigens. 65 (4): 301–69. doi:10.1111/j.1399-0039.2005.00379.x. PMID 15787720.
- ↑ derived from IMGT/HLA
- ↑ 4.00 4.01 4.02 4.03 4.04 4.05 4.06 4.07 4.08 4.09 4.10 4.11 4.12 4.13 Middleton D, Menchaca L, Rood H, Komerofsky R (2003). "New allele frequency database: http://www.allelefrequencies.net". Tissue Antigens. 61 (5): 403–7. PMID 12753660. External link in
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