Hairy cell leukemia classification
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Haytham Allaham, M.D. [2], Vamsikrishna Gunnam M.B.B.S [3]; Grammar Reviewer: Natalie Harpenau, B.S.[4]
Overview
- Hairy cell leukemia may be classified into two sub-types which include hairy cell leukemia (classic) and hairy cell leukemia (variant).
Classification
- Hairy cell leukemia may be classified into two sub-types which include:[1][2][3][4]
- Hairy cell leukemia (classic)
- Hairy cell leukemia (variant)
- Hairy cell leukemia (variant) is still considered a provisional entity at this time, as the WHO is unable to recognize it as distinct disease due to insufficient evidence.[5]
- The chart below illustrates characteristic findings associated with each sub-type:[6]
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Hairy cell leukemia | Hairy cell leukemia variant | ||||||||||||||||||||||||||||||||||
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References
- ↑ Matutes, E; Wotherspoon, A; Catovsky, D (2003). "The variant form of hairy-cell leukaemia". Best Practice & Research Clinical Haematology. 16 (1): 41–56. doi:10.1016/S1521-6926(02)00086-5. ISSN 1521-6926.
- ↑ Arons, E.; Suntum, T.; Stetler-Stevenson, M.; Kreitman, R. J. (2009). "VH4-34+ hairy cell leukemia, a new variant with poor prognosis despite standard therapy". Blood. 114 (21): 4687–4695. doi:10.1182/blood-2009-01-201731. ISSN 0006-4971.
- ↑ Robak T (February 2011). "Hairy-cell leukemia variant: recent view on diagnosis, biology and treatment". Cancer Treat. Rev. 37 (1): 3–10. doi:10.1016/j.ctrv.2010.05.003. PMID 20558005.
- ↑ Robak, T.; Matutes, E.; Catovsky, D.; Zinzani, P. L.; Buske, C. (2015). "Hairy cell leukaemia: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up". Annals of Oncology. 26 (suppl 5): v100–v107. doi:10.1093/annonc/mdv200. ISSN 0923-7534.
- ↑ Campo E, Swerdlow SH, Harris NL, Pileri S, Stein H, Jaffe ES (2011). "The 2008 WHO classification of lymphoid neoplasms and beyond: evolving concepts and practical applications". Blood. 117 (19): 5019–32. doi:10.1182/blood-2011-01-293050. PMC 3109529. PMID 21300984.
- ↑ Matutes E (2006). "Immunophenotyping and differential diagnosis of hairy cell leukemia". Hematol Oncol Clin North Am. 20 (5): 1051–63. doi:10.1016/j.hoc.2006.06.012. PMID 16990106.