Hamartoma MRI

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Maria Fernanda Villarreal, M.D. [2] Vamsikrishna Gunnam M.B.B.S [3]

Overview

MRI is the modality of choice for assessment of hypothalamic, spleen, kidney, and other abdominal hamartomas. On MRI, hamartoma is characterized by a heterogeneous signal in T1 and high signal due to fat and cartilaginous components in T2.

MRI may be helpful in the diagnosis of hamartomas. Findings on MRI suggestive of hamartomas include:^[1]^[2]^[3]

T1: isointense to cerebral cortex
T1 contrast: no contrast enhancement
T2: iso to hyperintense to cerebral cortex, the higher the proportion of glial cells, the higher the T2 signal.
MR spectroscopy
- Reduced NAA/C
- Increased myo inositol
- Increased Cho/Cr compared to the amygdala has also been reported.

Hypothalamic Hamartoma

Biliar Hamartomas

↑ Hypothalamic hamartoma.Dr Donna D'Souza et al. Radiopedia.http://radiopaedia.org/articles/pulmonary-hamartoma-1 Accessed on December 09, 2015
↑ Leiter Herrán F, Restrepo CS, Alvarez Gómez DI, Suby-Long T, Ocazionez D, Vargas D (March 2017). "Hamartomas from head to toe: an imaging overview". Br J Radiol. 90 (1071): 20160607. doi:10.1259/bjr.20160607. PMC 5601532. PMID 27936889.
↑ Saleem SN, Said AH, Lee DH (2007). "Lesions of the hypothalamus: MR imaging diagnostic features". Radiographics. 27 (4): 1087–108. doi:10.1148/rg.274065123. PMID 17620469.