Harrington–Hollingsworth Experiment

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Title of a 1950 experiment in hematology, where the academic staff of Barnes Hospital gave themselves transfusions of the plasma from a patient with ITP to observe the effect on platelet counts in normal subjects. The staff observed reduced platelet counts that recovered after a period of several days. This experiment established the autoimmune etiology of ITP. ^[1] ^[2]

References

↑ Schwartz RS (2007). "Immune thrombocytopenic purpura--from agony to agonist". N. Engl. J. Med. 357 (22): 2299–301. doi:10.1056/NEJMe0707126. PMID 18046034.
↑ HARRINGTON WJ, MINNICH V, HOLLINGSWORTH JW, MOORE CV (1951). "Demonstration of a thrombocytopenic factor in the blood of patients with thrombocytopenic purpura". J. Lab. Clin. Med. 38 (1): 1–10. PMID 14850832.

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[pmid18046034-1] Schwartz RS (2007). "Immune thrombocytopenic purpura--from agony to agonist". N. Engl. J. Med. 357 (22): 2299–301. doi:10.1056/NEJMe0707126. PMID 18046034.

[pmid14850832-2] HARRINGTON WJ, MINNICH V, HOLLINGSWORTH JW, MOORE CV (1951). "Demonstration of a thrombocytopenic factor in the blood of patients with thrombocytopenic purpura". J. Lab. Clin. Med. 38 (1): 1–10. PMID 14850832.

[1]

[2]

Harrington–Hollingsworth Experiment

References

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