Hemophagocytic lymphohistiocytosis overview

Hemophagocytic lymphohistiocytosis Microchapters
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Hemophagocytic lymphohistiocytosis (HLH) is an uncommon hematologic disorder in which the immune system produces too many activated immune cells (lymphocytes) called T cells, natural killer cells, B cells, and macrophages (histiocytes). Excessive amounts of immune system proteins called cytokines are also produced.