Hepatitis C/Ultrasound

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: Varun Kumar, M.B.B.S. [2]; Assistant Editor-In-Chief: Nina Axiotakis [3]

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [4]

Overview

Ultrasound may reveal no findings in early HCV infection. Changes in contour, nodularity, echogenic and vascular changes may all be signs of development of cirrhosis or hepatocellular carcinoma. Frequent sonography may be helpful among patients with chronic hepatitis C to monitor for potential complications.

Ultrasound

There are no specific findings on ultrasound for hepatitis C virus. Nonetheless, ultrasound may show findings consistent with complications induced by the disease, namely cirrhosis and hepatocellular carcinoma. Frequent sonography may be helpful among patients with chronic hepatitis C to monitor for potential complications.

Ultrasound Findings of Cirrhosis

Ultrasound findings are as follows:

  • Hepatomegaly
  • Changes in liver contour
  • Nodularity
  • Increase in echogenecity from focal fatty infiltration
  • Vascular changes:
    • Flow across both portal and systemic circulation increases
    • Resistive index increases in end stage liver disease
    • Vessels appear elongated and tortuous, called "corkscrewing" of the vessels
    • Doppler ultrasound may show spontaneous shunts
  • Splenomegaly and collaterals from portal hypertension may be noted.

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Ultrasound Findings of Hepatocellular Carcinoma[1][2]

References

  1. Ignee A, Weiper D, Schuessler G, Teuber G, Faust D, Dietrich CF (2005). "Sonographic characterisation of hepatocellular carcinoma at time of diagnosis". Z Gastroenterol. 43 (3): 289–94. doi:10.1055/s-2004-813815. PMID 15765302.
  2. Bennett GL, Krinsky GA, Abitbol RJ, Kim SY, Theise ND, Teperman LW (2002). "Sonographic detection of hepatocellular carcinoma and dysplastic nodules in cirrhosis: correlation of pretransplantation sonography and liver explant pathology in 200 patients". AJR Am J Roentgenol. 179 (1): 75–80. doi:10.2214/ajr.179.1.1790075. PMID 12076908.

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