Hyperparathyroidism epidemiology and demographics
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Anmol Pitliya, M.B.B.S. M.D.[2]
Overview
Primary hyperparathyroidism is the 3rd most common endocrine disorder. Highest incidence of primary hyperparathyroidism is in post-menopausal women.The incidence of primary hyperparathyroidism is approximately 0.4 to 21.6 per 100,000 person years. The prevalence of primary hyperparathyroidism is approximately .01 to .07 per 100,000 individuals. The incidence of primary hyperparathyroidism increases with age. Primary hyperparathyroidism usually affects individuals of African-American race. Women are more commonly affected by primary hyperparathyroidism than men. The women to men ratio is approximately 3 to 1. Difference in gender specific incidence of primary hyperparathyroidism becomes more pronounced with advancing age. There is insufficient data on epidemiology and demographics of secondary and tertiary hyperparathyroidism.
Epidemiology and Demographics
Primary hyperparathyroidism
Primary hyperparathyroidism is the 3rd most common endocrine disorder. Highest incidence of primary hyperparathyroidism is in post-menopausal women.[1] Epidemiology and demographics of primary hyperparathyroidism is as follows:[2]
Incidence
- The incidence of primary hyperparathyroidism is approximately 0.4 to 21.6 per 100,000 person years.
Prevalence
- The prevalence of primary hyperparathyroidism is approximately .01 to .07 per 100,000 individuals.
Age
- The incidence of primary hyperparathyroidism increases with age.
- In individuals age < 50 years, the incidence of primary hyperparathyroidism ranges from a low of 12 per 100,000 person years to a high of 24 per 100,000 per person years.
Race
- Primary hyperparathyroidism usually affects individuals of African-American race.
- The incidence of primary hyperparathyroidism according to race is as follows:
| Incidence of Primary hyperparathyroidism according to race | ||
|---|---|---|
| Race | Gender (incidence per 100,000 person years) | |
| Women | Men | |
| African-American | 92 | 46 |
| White | 81 | 29 |
| Asian | 52 | 28 |
| Hispanic | 49 | 17 |
| Other race | 25 | 6 |
Gender
- Women are more commonly affected by primary hyperparathyroidism than men. The women to men ratio is approximately 3 to 1.
- In women, the incidence of primary hyperparathyroidism ranges from a low of 34 per 100,000 person years to a high of 120 per 100,000 person years with an average incidence of 66 per 100,000 person years.
- In men, the incidence of primary hyperparathyroidism ranges from a low of 13 per 100,000 person years to a high of 36 per 100,000 person years with an average incidence of 24 per 100,000 person years.
- Difference in gender specific incidence of primary hyperparathyroidism becomes more pronounced with advancing age.
| Incidence of primary hyperparathyroidism in different age group | ||
|---|---|---|
| Age group | Gender (incidence per 100,000 person years) | |
| Women | Men | |
| Age < 50 years | 12-24 | 12-24 |
| Age 50 - 59 years | 80 | 36 |
| Age 70-79 years | 196 | 95 |
Secondary and Tertiary Hyperparathyroidism
There is insufficient data on epidemiology and demographics of secondary and tertiary hyperparathyroidism.
References
- ↑ Fraser WD (2009). "Hyperparathyroidism". Lancet. 374 (9684): 145–58. doi:10.1016/S0140-6736(09)60507-9. PMID 19595349.
- ↑ Yeh MW, Ituarte PH, Zhou HC, Nishimoto S, Liu IL, Harari A, Haigh PI, Adams AL (2013). "Incidence and prevalence of primary hyperparathyroidism in a racially mixed population". J. Clin. Endocrinol. Metab. 98 (3): 1122–9. doi:10.1210/jc.2012-4022. PMC 3590475. PMID 23418315.