Hyperventilation syndrome laboratory findings

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1], Farman Khan, MD, MRCP [2]

Laboratory Findings

Arterial blood gas (ABG) shows compensated respiratory alkalosis in most of the cases. The pH is usually near normal, with a low PaCO₂ and a low bicarbonate level. ABG sampling is also useful in ruling out toxicity from carbon monoxide poisoning. Toxicology screening is indicated to rule out any acute intoxication with drugs. If acute pulmonary embolism is included in the differential, then a quantitative enzyme-linked immunosorbent assay (ELISA) D-dimer assay may be helpful. It has good negative predictive value.