IHH

Indian hedgehog homolog (Drosophila)
PDB rendering based on 1vhh.
Available structures PDB Ortholog search: Template:Homologene2PDBe PDBe, Template:Homologene2uniprot RCSB List of PDB id codes 1vhh​
Identifiers
Symbols	IHH ; BDA1; HHG2
External IDs	Template:OMIM5 Template:MGI HomoloGene: 22586
Gene ontology Molecular function Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Template:GNF GO Biological process Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO
RNA expression pattern
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Indian hedgehog homolog (Drosophila), also known as IHH, is a human gene.

Further reading

• Marigo V, Roberts DJ, Lee SM; et al. (1995). "Cloning, expression, and chromosomal location of SHH and IHH: two human homologues of the Drosophila segment polarity gene hedgehog". Genomics. 28 (1): 44–51. PMID 7590746.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Chang DT, López A, von Kessler DP; et al. (1995). "Products, genetic linkage and limb patterning activity of a murine hedgehog gene". Development. 120 (11): 3339–53. PMID 7720571.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Porter JA, Young KE, Beachy PA (1996). "Cholesterol modification of hedgehog signaling proteins in animal development". Science. 274 (5285): 255–9. PMID 8824192.CS1 maint: Multiple names: authors list (link)
• Leek JP, Moynihan TP, Anwar R; et al. (1997). "Assignment of Indian hedgehog (IHH) to human chromosome bands 2q33-->q35 by in situ hybridization". Cytogenet. Cell Genet. 76 (3–4): 187–8. PMID 9186520.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Pepinsky RB, Zeng C, Wen D; et al. (1998). "Identification of a palmitic acid-modified form of human Sonic hedgehog". J. Biol. Chem. 273 (22): 14037–45. PMID 9593755.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Carpenter D, Stone DM, Brush J; et al. (1998). "Characterization of two patched receptors for the vertebrate hedgehog protein family". Proc. Natl. Acad. Sci. U.S.A. 95 (23): 13630–4. PMID 9811851.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Chuang PT, McMahon AP (1999). "Vertebrate Hedgehog signalling modulated by induction of a Hedgehog-binding protein". Nature. 397 (6720): 617–21. doi:10.1038/17611. PMID 10050855.
• Ito H, Akiyama H, Shigeno C; et al. (1999). "Hedgehog signaling molecules in bone marrow cells at the initial stage of fracture repair". Biochem. Biophys. Res. Commun. 262 (2): 443–51. doi:10.1006/bbrc.1999.1197. PMID 10462495.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Bak M, Hansen C, Friis Henriksen K, Tommerup N (2001). "The human hedgehog-interacting protein gene: structure and chromosome mapping to 4q31.21-->q31.3". Cytogenet. Cell Genet. 92 (3–4): 300–3. PMID 11435703.CS1 maint: Multiple names: authors list (link)
• Gao B, Guo J, She C; et al. (2001). "Mutations in IHH, encoding Indian hedgehog, cause brachydactyly type A-1". Nat. Genet. 28 (4): 386–8. doi:10.1038/ng577. PMID 11455389.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Gritli-Linde A, Lewis P, McMahon AP, Linde A (2001). "The whereabouts of a morphogen: direct evidence for short- and graded long-range activity of hedgehog signaling peptides". Dev. Biol. 236 (2): 364–86. doi:10.1006/dbio.2001.0336. PMID 11476578.CS1 maint: Multiple names: authors list (link)
• Kindblom JM, Nilsson O, Hurme T; et al. (2002). "Expression and localization of Indian hedgehog (Ihh) and parathyroid hormone related protein (PTHrP) in the human growth plate during pubertal development". J. Endocrinol. 174 (2): R1–6. PMID 12176676.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Cormier S, Delezoide AL, Benoist-Lasselin C; et al. (2002). "Parathyroid hormone receptor type 1/Indian hedgehog expression is preserved in the growth plate of human fetuses affected with fibroblast growth factor receptor type 3 activating mutations". Am. J. Pathol. 161 (4): 1325–35. PMID 12368206.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• McCready ME, Sweeney E, Fryer AE; et al. (2002). "A novel mutation in the IHH gene causes brachydactyly type A1: a 95-year-old mystery resolved". Hum. Genet. 111 (4–5): 368–75. doi:10.1007/s00439-002-0815-2. PMID 12384778.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Kirkpatrick TJ, Au KS, Mastrobattista JM; et al. (2003). "Identification of a mutation in the Indian Hedgehog (IHH) gene causing brachydactyly type A1 and evidence for a third locus". J. Med. Genet. 40 (1): 42–4. PMID 12525541.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Hellemans J, Coucke PJ, Giedion A; et al. (2003). "Homozygous mutations in IHH cause acrocapitofemoral dysplasia, an autosomal recessive disorder with cone-shaped epiphyses in hands and hips". Am. J. Hum. Genet. 72 (4): 1040–6. PMID 12632327.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Niemann C, Unden AB, Lyle S; et al. (2003). "Indian hedgehog and beta-catenin signaling: role in the sebaceous lineage of normal and neoplastic mammalian epidermis". Proc. Natl. Acad. Sci. U.S.A. 100 Suppl 1: 11873–80. doi:10.1073/pnas.1834202100. PMID 12917489.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Berman DM, Karhadkar SS, Maitra A; et al. (2003). "Widespread requirement for Hedgehog ligand stimulation in growth of digestive tract tumours". Nature. 425 (6960): 846–51. doi:10.1038/nature01972. PMID 14520411.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Garcia-Barceló MM, Lee WS, Sham MH; et al. (2004). "Is there a role for the IHH gene in Hirschsprung's disease?". Neurogastroenterol. Motil. 15 (6): 663–8. PMID 14651602.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)