Ifenprodil

Template:Chembox E number

Ifenprodil

Names
IUPAC name 4-[2-(4-benzylpiperidin-1-yl)-1-hydroxypropyl]phenol
Identifiers
3D model (JSmol)	Interactive image
ChEMBL	ChEMBL305187 N
ChemSpider	3561 Y
DrugBank	DB08954 N
ECHA InfoCard
KEGG	D08064 Y
PubChem CID	3689
InChI InChI=1S/C21H27NO2/c1-16(21(24)19-7-9-20(23)10-8-19)22-13-11-18(12-14-22)15-17-5-3-2-4-6-17/h2-10,16,18,21,23-24H,11-15H2,1H3 Y Key: UYNVMODNBIQBMV-UHFFFAOYSA-N Y InChI=1/C21H27NO2/c1-16(21(24)19-7-9-20(23)10-8-19)22-13-11-18(12-14-22)15-17-5-3-2-4-6-17/h2-10,16,18,21,23-24H,11-15H2,1H3 Key: UYNVMODNBIQBMV-UHFFFAOYAU
SMILES OC(c1ccc(O)cc1)C(N2CCC(CC2)Cc3ccccc3)C
Properties
Chemical formula	C21H27NO2
Molar mass	325.445
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YN ?)
Infobox references

WikiDoc Resources for Ifenprodil
Articles
Most recent articles on Ifenprodil Most cited articles on Ifenprodil Review articles on Ifenprodil Articles on Ifenprodil in N Eng J Med, Lancet, BMJ
Media
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Evidence Based Medicine
Cochrane Collaboration on Ifenprodil Bandolier on Ifenprodil TRIP on Ifenprodil
Clinical Trials
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Guidelines / Policies / Govt
US National Guidelines Clearinghouse on Ifenprodil NICE Guidance on Ifenprodil NHS PRODIGY Guidance FDA on Ifenprodil CDC on Ifenprodil
Books
Books on Ifenprodil
News
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Commentary
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Definitions
Definitions of Ifenprodil
Patient Resources / Community
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Healthcare Provider Resources
Symptoms of Ifenprodil Causes & Risk Factors for Ifenprodil Diagnostic studies for Ifenprodil Treatment of Ifenprodil
Continuing Medical Education (CME)
CME Programs on Ifenprodil
International
Ifenprodil en Espanol Ifenprodil en Francais
Business
Ifenprodil in the Marketplace Patents on Ifenprodil
Experimental / Informatics
List of terms related to Ifenprodil

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Ifenprodil is a selective inhibitor of the NMDA receptor. Its effect is specific to receptors composed of the NR1 (glycine-binding NMDA receptor subunit 1; GluN1) and NR2B (glutamate-binding NMDA receptor subunit 2; GluN2B) subunits.

NMDA receptors are multimeric ionotropic glutamate receptors composed of four subunits. NR1 is obligate for functional expression. Other subunits include NR2A, NR2B, and the more recently discovered NR3 subunits. Ifenprodil selectively blocks NMDA receptors containing the NR2B subunit.