Immunoblast
WikiDoc Resources for Immunoblast |
Articles |
---|
Most recent articles on Immunoblast Most cited articles on Immunoblast |
Media |
Powerpoint slides on Immunoblast |
Evidence Based Medicine |
Clinical Trials |
Ongoing Trials on Immunoblast at Clinical Trials.gov Clinical Trials on Immunoblast at Google
|
Guidelines / Policies / Govt |
US National Guidelines Clearinghouse on Immunoblast
|
Books |
News |
Commentary |
Definitions |
Patient Resources / Community |
Patient resources on Immunoblast Discussion groups on Immunoblast Patient Handouts on Immunoblast Directions to Hospitals Treating Immunoblast Risk calculators and risk factors for Immunoblast
|
Healthcare Provider Resources |
Causes & Risk Factors for Immunoblast |
Continuing Medical Education (CME) |
International |
|
Business |
Experimental / Informatics |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
An immunoblast is a lymphocyte that has been activated by an antigen, which will further undergo clonal expansion to increase the number of lymphocytes capable of binding to that antigen. Immunoblasts are the most immature members of the protective cells involved in an immune response.Activated B cells may differentiate into memory cells or plasma cells, while activated T cells may differentiate into memory cells or effector cells that aid in the immune response.
Histology
The majority of lymphocytes are small and have a thin rim of cytoplasm, 6-9 µm in diameter, about the same size as erythrocytes (diameter 7.5 µm). Large lymphocytes (12-18 µm in diameter) are probably activated, i.e. immunoblasts, with a paler and wider rim of cytoplasm and are often mistaken for monocytes.