Infectious Disease Project Antimicrobial Agents

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Antimicrobial Agents
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WikiDoc Infectious Disease Project — Antimicrobial Agents

Drug Categories:  Antibacterial  ●  Antimycobacterial  ●  Antiparasitic  ●  Antifungal  ●  Antiviral  ●  Antiretroviral


Alphabetical List:  A  ●  B  ●  C  ●  D  ●  E  ●  F  ●  G  ●  H  ●  I  ●  K  ●  L  ●  M  ●  N  ●  O  ●  P  ●  Q  ●  R  ●  S  ●  T  ●  V  ●  Z


Generic vs. Pharmaceutical Names:  Generic Name ➡︎ Pharmaceutical Name  ●  Pharmaceutical Name ➡︎ Generic Name


Risk Categories in Pregnancy:  Antibacterial  ●  Antimycobacterial  ●  Antifungal  ●  Antiparasitic  ●  Antiviral  ●  FDA Pregnancy Categories


Risk Categories for TdP or QTc Interval Prolongation  ●  CYP450 Isozymes Drug Interactions: Substrates, Inhibitors, Inducers


Antimicrobial Spectrum, Dosing Information, Adverse Reaction  ●  Dosage Adjustment in Renal or Hepatic Impairment


Antimicrobial Agents by Category

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Antimicrobial Agents in Alphabetical Order

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Generic Names and Pharmaceutical Names

Generic Name ➡︎ Pharmaceutical Name Return to Top

Generic Name Pharmaceutical Name Category
Abacavir Epzicom, Kivexa, Trizivir, Ziagen, Ziagenavir Antiretroviral
Acyclovir Lipsovir, Zovirax Antiviral
Adefovir dipivoxil Hepsera Antiviral
Albendazole Albenza, Eskazole, Zentel Antiparasitic
Amantadine hydrochloride Symadine, Symmetrel Antiviral
Amdinocillin Coactin Penicillin
Amikacin sulfate Biclin, Biklin, Likacin Aminoglycoside
Aminosalicylic acid Paser Antimycobacterial
Amoxicillin Amoxil, Clamoxyl, Doxamil, Hiconcil, Polymox, Prevpac, Trimox Penicillin
Amoxicillin/clavulanate potassium Amoxiclav, Augmentin, Augmentin XR, Calvepen Penicillin/β-lactamase inhibitor
Amphotericin B Amphocin, Fungilin, Fungizone Antifungal
Amphotericin B cholesteryl sulfate complex Amphotec Antifungal
Amphotericin B lipid complex Abelcet Antifungal
Amphotericin B liposomal AmBisome Antifungal
Ampicillin Penicillin
Ampicillin sodium Polycillin-N, Totacillin-N Penicillin
Ampicillin trihydrate Polycillin, Totacillin Penicillin
Ampicillin/probenecid Probampacin Penicillin/tubular secretion inhibitor
Ampicillin/sulbactam Bacimex, Combactam, Unasyn Penicillin/β-lactamase inhibitor
Anidulafungin Eraxis Antifungal
Artemether Coartem, Paluther, Riamet Antimalarial
Artesunate Plasmotrim Antimalarial
Atazanavir Reyataz Protease inhibitor
Atovaquone Mepron, Wellvone Antiparasitic
Atovaquone/proguanil Malarone Antimalarial
Azithromycin Azitromax, Sumamed, Zithromax, Zithromax Tri-Pak, Zitromax, Zmax, Z-Pak Azalide
Azlocillin Securopen Penicillin
Aztreonam Azactam, Monobac, Primbactam, Urobactam Monobactam
Bacampicillin Ambaxin, Bacampicin, Penglobe, Spectrobid Penicillin
Bacitracin Baci-IM Polypeptide
Balofloxacin Baloxin Fluoroquinolone
Bithionol Bitin, Lorothidol Antiparasitic
Boceprevir Victrelis Antiviral (hepatitis C)
Butoconazole nitrate Femstat 3, Gynazole-1, Gynomyk, Mycelex-3 Antifungal
Capreomycin sulfate Capastat Sulfate Antimycobacterial
Carbenicillin indanyl sodium Penicillin
Carbol-fuchsin Fungol Antifungal
Caspofungin Cancidas Antifungal
Cefaclor Distaclor, Keftid, Vercef Cephalosporin
Cefadroxil Baxam, Cefamox, Duracef, Duricef, Ultracef Cephalosporin
Cefamandole nafate Mandokef, Mandol Cephalosporin
Cefazolin sodium Ancef, Cefacidal, Cefamezin, Zolicef Cephalosporin
Cefdinir Cefzon, Omnicef Cephalosporin
Cefditoren pivoxil Spectracef Cephalosporin
Cefepime Maxcef, Maxipime Cephalosporin
Cefixime Cefspan, Denvar, Suprax Cephalosporin
Cefonicid sodium Monocid Cephalosporin
Cefoperazone sodium Cefobid, Cefodie, Cefoperazin Cephalosporin
Cefoperazone/sulbactam Sulperazon, Sulperazone Cephalosporin/β-lactamase inhibitor
Ceforanide Precef Cephalosporin
Cefotaxime sodium Claforan Cephalosporin
Cefotetan disodium Cephalosporin
Cefoxitin sodium Mefoxitin Cephalosporin
Cefpirome Cedixen, Cefrom, Cefron Cephalosporin
Cefpodoxime proxetil Orelox, Podomexef, Vantin Cephalosporin
Cefprozil Cefzil, Procef Cephalosporin
Cefsulodin Cefomonil, Monaspor Cephalosporin
Ceftaroline Teflaro Cephalosporin
Ceftazidime Ceptaz, Fortam, Fortaz, Fortum, Kefadim, Tazicef, Tazidime Cephalosporin
Ceftibuten Cedax, Keimax Cephalosporin
Ceftizoxime sodium Cefizox Cephalosporin
Ceftobiprole Zeftera Cephalosporin
Ceftriaxone sodium Rocephalin, Rocephin, Rocephine Cephalosporin
Cefuroxime axetil Ceftin, Zinnat Cephalosporin
Cefuroxime sodium Kefurox, Zinacef Cephalosporin
Cephalexin Cefanex, Ceporex, Keflex Cephalosporin
Cephalothin sodium Ceporacin, Keflin Cephalosporin
Cephapirin sodium Cefadyl Cephalosporin
Cephradine Anspor, Lisacef, Velosef Cephalosporin
Chloramphenicol Chloromycetin Chloramphenicol
Chloramphenicol palmitate Chloromycetin Palmitate Chloramphenicol
Chloramphenicol sodium succinate Chloromycetin Sodium Succinate Chloramphenicol
Chloroquine hydrochloride Aralen Hydrochloride Antimalarial
Chloroquine phosphate Aralen Phosphate Antimalarial
Ciclopirox Loprox Antifungal
Cidofovir Vistide Antiviral
Cinoxacin Quinolone
Ciprofloxacin hydrochloride Ciflox, Ciloxan, Cipro, Ciprodex, Cipro HC, Ciproxin, Cipro XR, Proquin XR Fluoroquinolone
Ciprofloxacin lactate Cipro IV Fluoroquinolone
Clarithromycin Biaxin, Biaxin XL, Biclar, Klacid, Prevpac, Zeclar Macrolide
Clindamycin hydrochloride Cleocin, Dalacin C Lincosamide
Clindamycin palmitate hydrochloride Cleocin Pediatric Lincosamide
Clindamycin phosphate Cleocin Phosphate Lincosamide
Clioquinol Corque, Diproform Antifungal
Clofazimine Lampren, Lamprene Antimycobacterial
Clotrimazole Canesten, Cruex, Desenex, FemCare, Fungoid, Gyne-Lotrimin, Lotrimin, Lotrisone, Mycelex Antifungal
Cloxacillin sodium Bactopen, Cloxapen, Orbenin Penicillin
Colistimethate sodium Coly-Mycin M Polymyxin
Cyclacillin Calthor, Cyclapen Penicillin
Cycloserine Seromycin Antimycobacterial
Dapsone Sulfone
Daptomycin Cidecin, Cubicin, Dapcin Cyclic lipopeptide
Darunavir Prezista Antiretroviral
Dehydroemetine Mebadin Amebicide
Delavirdine Rescriptor Antiretroviral
Demeclocycline hydrochloride Declomycin Tetracycline
Dicloxacillin sodium Diclocil, Dycill, Pathocil Penicillin
Didanosine Videx, Videx EC Antiretroviral
Diethylcarbamazine Hetrazan, DEC Antiparasitic
Diloxanide furoate Entamide, Furamide Antiparasitic
Dirithromycin Dynabac, Dynabac D5-Pak Macrolide
Dolutegravir Tivicay Antiretroviral
Doripenem Doribax, Finibax Carbapenem
Doxycycline calcium Vibramycin Calcium Tetracycline
Doxycycline hyclate Doryx, Doxy 100, Doxy Caps, Periostat, Vibramycin Hyclate, Vibra-Tabs Tetracycline
Doxycycline monohydrate Vibramycin Monohydrate, Monodox Tetracycline
Econazole nitrate Ecostatin, Gyno-Pevaryl, Pevisone, Spectazole Antifungal
Efavirenz Atripla, Emtriva, Coviracil, Stocrin, Sustiva, Truvada, Viraday Antiretroviral
Elvitegravir Stribild Antiretroviral
Emtricitabine Emtriva, Stribild, Truvada, Complera Antiretroviral
Enfuvirtide Fuzeon Fusion inhibitor
Enoxacin Comprecin, Enoxor, Penetrex Fluoroquinolone
Entecavir Baraclude Antiviral
Ertapenem Invanz Carbapenem
Erythromycin Akne-Mycin, Benzamycin, E-Base, E-Mycin, ERYC, Ery-Tab, PCE, Robimycin Macrolide
Erythromycin estolate Ilosone Macrolide
Erythromycin ethylsuccinate E.E.S., EryPed, Eryzole, E.S.P., Pediazole, Sulfimycin Macrolide
Erythromycin gluceptate Ilotycin Macrolide
Erythromycin lactobionate Erythrocin Macrolide
Erythromycin stearate Erythrocin Stearate, Wyamycin Macrolide
Ethambutol hydrochloride Myambutol, Servambutol Antimycobacterial
Ethionamide Trecator Antimycobacterial
Etravirine Intelence Antiretroviral
Famciclovir Famvir Antiviral
Fidaxomicin Dificid Macrolide
Flomoxef Flumarin Cephalosporin
Flucloxacillin Floxapen, Flucil, Flucillin, Fluclox Penicillin
Fluconazole Diflucan Antifungal
Flucytosine Ancobon, Ancotil Antifungal
Fosamprenavir Lexiva, Telzir Antiretroviral
Foscarnet sodium Foscavir Antiviral
Fosfomycin tromethamine Monuril, Monurol Urinary anti-infective
Furazolidone Furoxone Antiprotozoal
Ganciclovir sodium Cymevene, Cytovene, Vitrasert Antiviral
Gatifloxacin Zymar Fluoroquinolone
Gemifloxacin Factive Fluoroquinolone
Gentamicin sulfate Cidomycin, Garamycin, Genoptic, Jenamicin, Storz-G Aminoglycoside
Gentian violet Antifungal
Griseofulvin Fulcin, Fulvicin P/G, Fulvicin U/F, Grifulvin V, Grisactin, Grisactin Ultra, Grisovin, Gris-PEG Antifungal
Halofantrine Halfan Antiparasitic
Hydroxychloroquine sulfate Plaquenil Sulfate Antimalarial
Imipenem/cilastatin Primaxin, Tienam Carbapenem
Indinavir Crixivan Protease inhibitor
Interferon alfa-2a recombinant Roferon-A Antiviral
Interferon alfa-2b recombinant Intron A, Rebetron Antiviral
Interferon alfacon-1 Infergen Antiviral
Interferon alfa-n3 Alferon N Antiviral
Iodoquinol Yodoxin M, Yodoxin Amebicide
Isoniazid Laniazid, Nydrazid, Rifamate, Rifater, Rifinah, Rimactane/INH Antimycobacterial
Itraconazole Sporanox Antifungal
Ivermectin Mectizan, Stromectol Antiparasitic
Josamycin Josalid Macrolide
Kanamycin sulfate Anamid Aminoglycoside
Ketoconazole Fungoral, Nizoral Antifungal
Lamivudine (3TC) Combivir, Epivir, Epivir-HBV, Epzicom, Kivexa, Trizivir, Zeffix Antiretroviral
Levofloxacin Cravit, Levaquin, Quixin, Tavanic Fluoroquinolone
Lincomycin hydrochloride Lincocin Lincosamide
Linezolid Zyvox, Zyvoxam Oxazolidinone
Lomefloxacin hydrochloride Maxaquin, Okacin, Uniquin Fluoroquinolone
Lopinavir/ritonavir Kaletra Antiretrovirals
Loracarbef Lorabid Carbacephem
Lumefantrine Coartem Antimalarial
Mafenide Sulfamylon Sulfonamide
Maraviroc Selzentry, Celsentri Antiretroviral
Mebendazole Anthelmintic
Mefloquine Lariam Antimalarial
Meglumine antimonate Glucantim, Glucantime Antiparasitic
Melarsoprol Arsobal, Mel B Antiparasitic
Meropenem Meronem, Merrem Carbapenem
Methacycline Rondomycin Tetracycline
Methenamine hippurate Hiprex, Urex Urinary anti-infective
Methenamine mandelate Mandelamine Urinary anti-infective
Metronidazole Elyzol, Flagyl, Flagyl ER, Flagyl 375, Helidac, MetroGel, Protostat, Rozex Nitroimidazole
Mezlocillin sodium Baypen Penicillin
Micafungin Mycamine Antifungal
Miconazole Daktacort, Daktarin, Gyno-Daktarin, Micatin, Monistat Antifungal
Minocycline hydrochloride Dynacin, Minocin, Myrac, Vectrin Tetracycline
Moxalactam Moxam Cephalosporin
Moxifloxacin Avelox, Vigamox Fluoroquinolone
Mupirocin Bactroban Pseudomonic acid
Nadifloxacin Acuatim, Nadoxin, Nadixa Fluoroquinolone
Nafcillin sodium Nafcil, Unipen Penicillin
Naftifine Naftin Antifungal
Nalidixic acid NegGram Quinolone
Natamycin Natacyn Antifungal
Nelfinavir Viracept Protease inhibitor
Neomycin sulfate Kenacomb, Maxitrol, Mycifradin Sulfate, Neosporin Aminoglycoside
Netilmicin sulfate Netilyn, Netromycin Aminoglycoside
Nevirapine Viramune Antiretroviral
Niclosamide Niclocide, Yomesan Anthelmintic
Nifurtimox Bayer 2502, Lampit Antiparasitic
Nitazoxanide Alinia Antiprotozoal
Nitrofurantoin Furadantin, Macrobid, Macrodantin Urinary anti-infective
Norfloxacin Floxacin, Noroxin Fluoroquinolone
Novobiocin sodium Albamycin
Nystatin Kenacomb, Mycostatin, Mycostatin Filmlok, Nilstat Antifungal
Ofloxacin Exocin, Floxin, Ocuflox, Tarivid Fluoroquinolone
Oritavancin diphosphate Glycopeptide
Oseltamivir phosphate Tamiflu Antiviral
Oxacillin sodium Penicillin
Oxamniquine Mansil Anthelmintic
Oxiconazole nitrate Oxistat Antifungal
Oxolinic acid Oribiox Quinolone
Oxytetracycline hydrochloride Uri-Tet, Urobiotic Tetracycline
Palivizumab Synagis Antiviral
Paromomycin sulfate Humatin Amebicide
Pazufloxacin Pasil, Pazucross Fluoroquinolone
Pefloxacin Peflacine, Peflox Fluoroquinolone
Peginterferon alfa-2a Pegasys Antiviral
Peginterferon alfa-2b Pegetron, PEG-Intron Antiviral
Penciclovir Denavir, Vectavir Antiviral
Penicillin G benzathine Bicillin, Bicillin C-R, Bicillin C-R 900/300, Bicillin L-A, Permapen Penicillin
Penicillin G + phenoxymethyl penicillin Kesso-pen Penicillin
Penicillin G potassium Pfizerpen Penicillin
Penicillin G procaine Bicillin C-R, Bicillin C-R 900/300, Crysticillin AS, Pfizerpen-AS, Wycillin Penicillin
Penicillin G sodium Penicillin
Penicillin V potassium Penicillin
Pentamidine isethionate NebuPent, Pentacarinat, Pentam Antiprotozoal
Phenazopyridine/sulfisoxazole Azo Gantrisin Symptomatic bladder therapy/sulfonamide
Pipemidic acid Dolcol Quinolone
Piperacillin sodium Pipracil, Pipril Penicillin
Piperacillin sodium/tazobactam sodium Tazocin, Zosyn Penicillin/β-lactamase inhibitor
Piperazine citrate Anthelmintic
Pivmecillinam Mecillin 200, Selexid Penicillin
Polymyxin B sulfate Aerosporin, Neosporin Polymyxin
Posaconazole Noxafil Antifungal
Praziquantel Biltricide Anthelmintic
Primaquine phosphate Antimalarial
Proguanil Paludrine Antiparasitic
Pyrantel pamoate Antiminth, Ascarel, Combantrin, Pin-X, Reese's Pinworm Medicine Anthelmintic
Pyrazinamide Rifater, Zinamide Antimycobacterial
Pyrimethamine Daraprim Antimalarial
Quinacrine hydrochloride Atabrine Anthelmintic
Quinine sulfate Qualaquin Antimalarial
Quinupristin/dalfopristin Synercid Streptogramin
Raltegravir Isentress Antiretroviral
Retapamulin Altabax Anti-impetigo
Ribavirin Copegus, Pegetron, Rebetol, Rebetron, Ribasphere, Virazole Antiviral
Rifabutin Mycobutin Antimycobacterial
Rifampin Rifadin, Rifamate, Rifinah, Rimactane, Rimactane/INH Antimycobacterial
Rifapentine Priftin Antimycobacterial
Rifaximin Lumenax, Xifaxan Rifamycin
Rilpivirine Complera, Edurant Antiretroviral
Rimantadine Flumadine, Roflual Antiviral
Ritonavir Norvir Protease inhibitor
Rosoxacin Eradacil Quinolone
Roxithromycin Rulid, Rulide, Surlid Macrolide
Rufloxacin Uroflox Fluoroquinolone
Saquinavir Fortovase, Invirase Protease inhibitor
Sertaconazole Ertaczo Antifungal
Silver sulfadiazine Silvadene, Thermazene Sulfonamide
Sitafloxacin Gracevit Fluoroquinolone
Sodium stibogluconate Pentostam Antiparasitic
Sodium thiosulfate Versiclear Antifungal
Sparfloxacin Zagam Fluoroquinolone
Spiramycin Rovamycin, Rovamycine Macrolide
Stavudine (d4T) Zerit Antiretroviral
Streptomycin sulfate Aminoglycoside
Sulconazole Exelderm Antifungal
Sulfabenzamide/sulfacetamide/sulfathiazole Sultrin, Triple Sulfa Sulfonamide
Sulfadiazine Sulfonamide
Sulfamethizole Sulfonamide
Sulfamethoxazole Sulfonamide
Sulfanilamide AVC Sulfonamide
Sulfisoxazole Azo-Sulfisoxazole, Gantrisin Sulfonamide
Sulfisoxazole acetyl Eryzole, Pediazole Sulfonamide
Suramin Antrypol, Belganyl, Germanin, Naphuride Antiparasitic
Teicoplanin Targocid Glycopeptide
Telaprevir Incivek Antiviral (hepatitis C)
Telavancin Vibativ Lipopeptide
Telbivudine Tyzeka Antiviral
Telithromycin Ketek Ketolide
Tenofovir Atripla, Complera, Stribild, Truvada, Viraday, Viread Antiretroviral
Terbinafine Lamisil Antifungal
Terconazole Terazol, Zazole Antifungal
Tetracycline hydrochloride Achromycin V, Helidac, Panmycin, Robitet, Sumycin, Tetrachel, Tetralan Tetracycline
Thiabendazole Mintezol Anthelmintic
Thiacetazone Antimycobacterial
Ticarcillin disodium Tarcil Penicillin
Ticarcillin disodium/clavulanate potassium Timentin Penicillin/β-lactamase inhibitor
Tigecycline Tygacil Glycylcycline
Tinidazole Tindamax Antiparasitic
Tioconazole Vagistat-1 Antifungal
Tipranavir Aptivus Antiretroviral
Tobramycin sulfate Nebcina, Obracin, TobraDex, Tobrex Aminoglycoside
Tobramycin inhalation solution TOBI Aminoglycoside
Tolnaftate Mycil, Tinactin, Tinaderm Antifungal
Tosufloxacin Ozex, Tosacin Fluoroquinolone
Trifluridine Viroptic Antiviral
Trimethoprim Monotrim, Primsol, Proloprim, Trimopan, Trimpex Folate antagonist
Trimethoprim/sulfamethoxazole Bactrim, Bactrim DS, Cotrim, Cotrim D.S., Septra, Septra DS, Sulfatrim, Sulfoxaprim, Uroplus Folate antagonists
Trimetrexate glucuronate NeuTrexin Antiprotozoal
Tripanavir Aptivus Antiretroviral
Trisulfapyrimidines Sulfonamide
Troleandomycin Tao Macrolide
Undecylenic acid Fungi-Nail Antifungal
Valacyclovir Valtrex, Zelitrex Antiviral
Valganciclovir Valcyte Antiviral
Vancomycin hydrochloride Lyphocin, Vancocin, Vancoled, Vancor Glycopeptide
Vidarabine Vira-MP Antiviral
Voriconazole Vfend Antifungal
Zanamivir Relenza Antiviral
Zidovudine Combivir, Retrovir, Trizivir Antiretroviral

Pharmaceutical Name ➡︎ Generic Name Return to Top

Pharmaceutical Name Generic Name Category
Abelcet Amphotericin B lipid complex Antifungal
Achromycin V Tetracycline hydrochloride Tetracycline
Acuatim Nadifloxacin Fluoroquinolone
Aerosporin Polymyxin B sulfate Polymyxin
Akne-Mycin Erythromycin Macrolide
Albamycin Novobiocin sodium
Albenza Albendazole Antiparasitic
Alferon N Interferon alfa-n3 Antiviral
Alinia Nitazoxanide Antiprotozoal
Altabax Retapamulin Anti-impetigo
Ambaxin Bacampicillin Penicillin
AmBisome Amphotericin B liposomal Antifungal
Amoxiclav Amoxicillin/clavulanate potassium Penicillin/β-lactamase inhibitor
Amoxil Amoxicillin Penicillin
Amphocin Amphotericin B Antifungal
Amphotec Amphotericin B cholesteryl sulfate complex Antifungal
Anamid Kanamycin Aminoglycoside
Ancef Cefazolin sodium Cephalosporin
Ancobon Flucytosine Antifungal
Ancotil Flucytosine Antifungal
Anspor Cephradine Cephalosporin
Antiminth Pyrantel pamoate Anthelmintic
Antrypol Suramin Antiparasitic
Aptivus Tipranavir Antiretroviral
Aralen Hydrochloride Chloroquine hydrochloride Antimalarial
Aralen Phosphate Chloroquine phosphate Antimalarial
Arsobal Melarsoprol Antiparasitic
Ascarel Pyrantel pamoate Anthelmintic
Atabrine Quinacrine hydrochloride Anthelmintic
Atripla Efavirenz/tenofovir/emtricitabine Antiretroviral
Augmentin Amoxicillin/clavulanate potassium Penicillin/β-lactamase inhibitor
Augmentin XR Amoxicillin/clavulanate potassium Penicillin/β-lactamase inhibitor
AVC Sulfanilamide Sulfonamide
Avelox Moxifloxacin Fluoroquinolone
Azactam Aztreonam Monobactam
Azitromax Azithromycin Azalide
Azo-Sulfisoxazole Sulfisoxazole Sulfonamide
Bacampicin Bacampicillin Penicillin
Baci-IM Bacitracin Polypeptide
Bacimex Ampicillin/sulbactam Penicillin/β-lactamase inhibitor
Bactopen Cloxacillin Penicillin
Bactrim, Bactrim DS Trimethoprim/sulfamethoxazole Folate antagonists
Bactroban Mupirocin Pseudomonic acid
Baloxin Balofloxacin Fluoroquinolone
Baraclude Entecavir Antiviral
Baxam Cefadroxil Cephalosporin
Bayer 2502 Nifurtimox Antiparasitic
Baypen Mezlocillin Penicillin
Belganyl Suramin Antiparasitic
Benzamycin Erythromycin/benzoyl peroxide Macrolide/antiseptic
Biaxin, Biaxin XL Clarithromycin Macrolide
Bicillin C-R Penicillin G procaine/benzathine Penicillin
Bicillin L-A Penicillin G benzathine Penicillin
Biclar Clarithromycin Macrolide
Biclin Amikacin Aminoglycoside
Biklin Amikacin Aminoglycoside
Biltricide Praziquantel Anthelmintic
Bitin Bithionol Antiparasitic
Calthor Cyclacillin Penicillin
Cancidas Caspofungin Antifungal
Canesten Clotrimazole Antifungal
Capastat Sulfate Capreomycin sulfate Polypeptide
Cedax Ceftibuten Cephalosporin
Cedixen Cefpirome Cephalosporin
Cefacidal Cefazolin Cephalosporin
Cefadel Cefmetazole Cephalosporin
Cefadyl Cephapirin sodium Cephalosporin
Cefamezin Cefazolin Cephalosporin
Cefamox Cefadroxil Cephalosporin
Cefanex Cephalexin Cephalosporin
Cefizox Ceftizoxime sodium Cephalosporin
Cefmetazon Cefmetazole Cephalosporin
Cefobid Cefoperazone Cephalosporin
Cefodie Cefoperazone Cephalosporin
Cefomonil Cefsulodin Cephalosporin
Cefoperazin Cefoperazone/lidocaine Cephalosporin
Cefrom Cefpirome Cephalosporin
Cefron Cefpirome Cephalosporin
Cefspan Cefixime Cephalosporin
Ceftin Cefuroxime axetil Cephalosporin
Cefzil Cefprozil Cephalosporin
Cefzon Cefdinir Cephalosporin
Celsentri Maraviroc Antiretroviral
Ceporacin Cephalothin Cephalosporin
Ceporex Cephalexin Cephalosporin
Ceptaz Ceftazidime Cephalosporin
Chloromycetin Chloramphenicol Chloramphenicol
Chloromycetin Palmitate Chloramphenicol palmitate Chloramphenicol
Chloromycetin Sodium Succinate Chloramphenicol sodium succinate Chloramphenicol
Cidecin Daptomycin Cyclic lipopeptide
Cidomycin Gentamicin Aminoglycoside
Ciflox Ciprofloxacin hydrochloride Fluoroquinolone
Ciloxan Ciprofloxacin hydrochloride Fluoroquinolone
Cipro Ciprofloxacin hydrochloride Fluoroquinolone
Ciprodex Ciprofloxacin/dexamethasone Fluoroquinolone/steroid
Cipro HC Ciprofloxacin/hydrocortisone Fluoroquinolone/steroid
Cipro IV Ciprofloxacin lactate Fluoroquinolone
Ciproxin Ciprofloxacin hydrochloride Fluoroquinolone
Cipro XR Ciprofloxacin Fluoroquinolone
Claforan Cefotaxime sodium Cephalosporin
Clamoxyl Amoxicillin Penicillin
Clavepen Amoxicillin/clavulanate potassium Penicillin/β-lactamase inhibitor
Cleocin Clindamycin hydrochloride Lincosamide
Cleocin Pediatric Clindamycin palmitate hydrochloride Lincosamide
Cleocin Phosphate Clindamycin phosphate Lincosamide
Cloxapen Cloxacillin sodium Penicillin
Coactin Amdinocillin Penicillin
Coartem Artemether/Lumefantrine Antimalarial
Coly-Mycin M Colistimethate sodium Polymyxin
Combactam Ampicillin/sulbactam Penicillin/β-lactamase inhibitor
Combantrin Pyrantel pamoate Anthelmintic
Combivir Lamivudine/zidovudine Antiretroviral
Complera Emtricitabine/rilpivirine/tenofovir Antiretroviral
Comprecin Enoxacin Fluoroquinolone
Copegus Ribavirin Antiviral
Corque Clioquinol/hydrocortisone Antifungal
Cotrim, Cotrim D.S. Trimethoprim/sulfamethoxazole Folate antagonists
Coviracil Emtricitabine Antiretroviral
Cravit Levofloxacin Fluoroquinolone
Crixivan Indinavir Protease inhibitor
Cruex Clotrimazole Antifungal
Crysticillin Penicillin G procaine Penicillin
Cubicin Daptomycin Cyclic lipopeptide
Cyclapen Cyclacillin Penicillin
Cymevene Ganciclovir sodium Antiviral
Cytovene Ganciclovir sodium Antiviral
Daktacort Miconazole/hydrocortisone Antifungal
Daktarin Miconazole Antifungal
Dalacin C Clindamycin hydrochloride Lincosamide
Dapcin Daptomycin Cyclic lipopeptide
Daraprim Pyrimethamine Antimalarial
DEC Diethylcarbamazine Antiparasitic
Declomycin Demeclocycline hydrochloride Tetracycline
Denavir Penciclovir Antiviral
Denvar Cefixime Cephalosporin
Desenex Clotrimazole Antifungal
Diclocil Dicloxacillin Penicillin
Dificid Fidaxomycin Macrolide
Diflucan Fluconazole Antifungal
Diproform Clioquinol/betamethasone Antifungal
Distaclor Cefaclor Cephalosporin
Dolcol Pipemidic acid Quinolone
Doribax Doripenem Carbapenem
Doryx Doxycycline hyclate Tetracycline
Doxamil Amoxicillin Penicillin
Doxy 100 Doxycycline hyclate Tetracycline
Doxy Caps Doxycycline hyclate Tetracycline
Duracef Cefadroxil Cephalosporin
Duricef Cefadroxil Cephalosporin
Dycill Dicloxacillin sodium Penicillin
Dynabac, Dynabac D5-Pak Dirithromycin Macrolide
Dynacin Minocycline Tetracycline
Dynapen Dicloxacillin Penicillin
E.E.S. Erythromycin ethylsuccinate Macrolide
E-Base Erythromycin Macrolide
Ecostatin Econazole Antifungal
Edurant Rilpivirine Antiretroviral
Elyzol Metronidazole Nitroimidazole
Emtriva Emtricitabine Antiretroviral
E-Mycin Erythromycin Macrolide
Enoxor Enoxacin Fluoroquinolone
Entamide Diloxanide furoate Antiparasitic
Epivir, Epivir-HBV Lamivudine (3TC) Antiretroviral
Epzicom Abacavir/lamivudine Antiretroviral
Eradacil Rosoxacin Quinolone
Eraxis Anidulafungin Antifungal
Ertaczo Sertaconazole Antifungal
ERYC Erythromycin Macrolide
EryPed Erythromycin ethylsuccinate Macrolide
Ery-Tab Erythromycin Macrolide
Erythrocin Erythromycin lactobionate Macrolide
Erythrocin Stearate Erythromycin stearate Macrolide
Eryzole Erythromycin ethylsuccinate/sulfisoxazole Macrolide/sulfonamide
Eskazole Albendazole Antiparasitic
E.S.P. Erythromycin ethylsuccinate/sulfisoxazole Macrolide/sulfonamide
Exelderm Sulconazole Antifungal
Exocin Ofloxacin Fluoroquinolone
Factive Gemifloxacin Fluoroquinolone
Famvir Famciclovir Antiviral
Femcare Clotrimazole Antifungal
Femstat 3 Butoconazole Antifungal
Finibax Doripenem Carbapenem
Flagyl Metronidazole Nitroimidazole
Flagyl ER Metronidazole Nitroimidazole
Flagyl 375 Metronidazole Nitroimidazole
Floxacin Norfloxacin Fluoroquinolone
Floxapen Flucloxacillin Penicillin
Floxin Ofloxacin Fluoroquinolone
Flucil Flucloxacillin Penicillin
Flucillin Flucloxacillin Penicillin
Fluclox Flucloxacillin Penicillin
Flumadine Rimantadine Antiviral
Flumarin Flomoxef Cephalosporin
Fortam Ceftazidime Cephalosporin
Fortaz Ceftazidime Cephalosporin
Fortovase Saquinavir Protease inhibitor
Fortum Ceftazidime Cephalosporin
Foscavir Foscarnet sodium Antiviral
Fulcin Griseofulvin Antifungal
Fulvicin P/G Griseofulvin Antifungal
Fulvicin U/F Griseofulvin Antifungal
Fungilin Amphotericin B Antifungal
Fungizone Amphotericin B Antifungal
Fungi-nail Undecylenic acid Antifungal
Fungoid Clotrimazole Antifungal
Fungol Carbol-fuchsin Antifungal
Fungoral Ketoconazole Antifungal
Furadantin Nitrofurantoin Urinary anti-infective
Furamide Diloxanide furoate Antiparasitic
Furoxone Furazolidone Antiprotozoal
Fuzeon Enfuvirtide Fusion inhibitor
Gantrisin Sulfisoxazole Sulfonamide
Garamycin Gentamicin Aminoglycoside
Geninax Garenoxacin Des-quinolone
Genoptic Gentamicin Aminoglycoside
Germanin Suramin Antiparasitic
Glucantim Meglumine antimonate Antiparasitic
Glucantime Meglumine antimonate Antiparasitic
Gracevit Sitafloxacin Fluoroquinolone
Grifulvin V Griseofulvin Antifungal
Grisactin Griseofulvin Antifungal
Grisactin Ultra Griseofulvin Antifungal
Grisovin Griseofulvin Antifungal
Gris-PEG Griseofulvin Antifungal
Gynazole-1 Butoconazole nitrate Antifungal
Gyne-Lotrimin Clotrimazole Antifungal
Gyno-Daktarin Miconazole Antifungal
Gynomyk Butoconazole Antifungal
Gyno-Pevaryl Econazole Antifungal
Halfan Halofantrine Antiparasitic
Helidac Bismuth/metronidazole/tetracycline Anti- Helicobacter
Hepsera Adefovir dipivoxil Antiviral
Hetrazan Diethylcarbamazine Antiparasitic
Hiconcil Amoxicillin Penicillin
Hiprex Methenamine hippurate Urinary anti-infective
Humatin Paromomycin sulfate Amebicide
Ilosone Erythromycin estolate Macrolide
Ilotycin Erythromycin gluceptate Macrolide
Incivek Telaprevir Antiretroviral
Infergen Interferon alfacon-1 Antiviral
Intelence Etravirine Antiretroviral
Intron A Interferon alfa-2b recombinant Antiviral
Invanz Ertapenem Carbapenem
Invirase Saquinavir Protease inhibitor
Isentress Raltegravir Antiretroviral
Isepacin Isepamicin Aminoglycoside
Jenamicin Gentamicin sulfate Aminoglycoside
Josalid Josamycin Macrolide
Kaletra Lopinavir/ritonavir Antiretroviral
Kefadim Ceftazidime Cephalosporin
Keflex Cephalexin Cephalosporin
Keflin Cephalothin sodium Cephalosporin
Kefurox Cefuroxime sodium Cephalosporin
Keimax Ceftibuten Cephalosporin
Kenacomb Neomycin/nystatin Aminoglycoside/antifungal
Kesso-pen Penicillin G/phenoxymethyl penicillin Penicillins
Ketek Telithromycin Ketolide
Kivexa Abacavir/lamivudine/zidovudine Antiretroviral
Klacid Clarithromycin Macrolide
Lamisil Terbinafine Antifungal
Lampit Nifurtimox Antiparasitic
Lampren Clofazimine Antimycobacterial
Lamprene Clofazimine Antimycobacterial
Laniazid Isoniazid Antimycobacterial
Lariam Mefloquine Antimalarial
Levaquin Levofloxacin Fluoroquinolone
Lexiva Fosamprenavir Antiretroviral
Likacin Amikacin Aminoglycoside
Lincocin Lincomycin Lincosamide
Lisacef Cephradine Cephalosporin
Loprox Ciclopirox Antifungal
Lorabid Loracarbef Carbacephem
Lorothidol Bithionol Antiparasitic
Lotrimin Clotrimazole Antifungal
Lotrisone Clotrimazole Antifungal
Lumenax Rifaximin Rifamycin
Lyphocin Vancomycin hydrochloride Glycopeptide
Macrobid Nitrofurantoin Urinary anti-infective
Macrodantin Nitrofurantoin Urinary anti-infective
Malarone Atovaquone/proguanil Antimalarial
Mandelamine Methenamine mandelate Urinary anti-infective
Mandokef Cefamandole Cephalosporin
Mandol Cefamandole Cephalosporin
Mansil Oxamniquine Anthelmintic
Maxaquin Lomefloxacin Fluoroquinolone
Maxcef Cefepime Cephalosporin
Maxipime Cefepime Cephalosporin
Maxitrol Dexamethasone/neomycin/polymyxin B Antifungal/polymyxin
Mebadin Dehydroemetine Amebicide
Mecillin 200 Pivmecillinam Penicillin
Mectizan Ivermectin Antiparasitic
Mefoxitin Cefoxitin Cephalosporin
Mel B Melarsoprol Antiparasitic
Mepron Atovaquone Antiparasitic
Meronem Meropenem Carbapenem
Merrem Meropenem Carbapenem
Metazol Cefmetazole sodium Cephalosporin
MetroGel Metronidazole Nitroimidazole
Micatin Miconazole Antifungal
Minocin Minocycline hydrochloride Tetracycline
Mintezol Thiabendazole Anthelmintic
Monaspor Cefsulodin Cephalosporin
Monistat Miconazole Antifungal
Monobac Aztreonam Monobactam
Monocid Cefonicid sodium Cephalosporin
Monodox Doxycycline monohydrate Tetracycline
Monotrim Trimethoprim Folate antagonist
Monuril Fosfomycin tromethamine Urinary anti-infective
Monurol Fosfomycin tromethamine Urinary anti-infective
Moxam Moxalactam Cephalosporin
Myambutol Ethambutol hydrochloride Antimycobacterial
Mycamine Micafungin Antifungal
Mycelex Clotrimazole Antifungal
Mycelex-3 Butoconazole Antifungal
Mycifradin Sulfate Neomycin sulfate Aminoglycoside
Mycil Tolnaftate Antifungal
Mycobutin Rifabutin Antimycobacterial
Mycostatin (Filmlok) Nystatin Antifungal
Myrac Minocycline Tetracycline
Nadixa Nadifloxacin Fluoroquinolone
Nadoxin Nadifloxacin Fluoroquinolone
Nafcil Nafcillin sodium Penicillin
Naftin Naftifine Antifungal
Naphuride Suramin Antiparasitic
Natacyn Natamycin Antifungal
Nebcina Tobramycin Aminoglycoside
NebuPent Pentamidine isethionate Antiprotozoal
NegGram Nalidixic acid Quinolone
Neosporin Neomycin/polymyxin B Aminoglycoside/polymyxin
Netilyn Netilmicin Aminoglycoside
Netromycin Netilmicin Aminoglycoside
NeuTrexin Trimetrexate Antiprotozoal
Niclocide Niclosamide Anthelmintic
Nilstat Nystatin Antifungal
Nizoral Ketoconazole Antifungal
Noroxin Norfloxacin Fluoroquinolone
Norvir Ritonavir Protease inhibitor
Noxafil Posaconazole Antifungal
Nydrazid Isoniazid Antimycobacterial
Nyotran Liposomal nystatin Antifungal
Obracin Tobramycin Aminoglycoside
Ocuflox Ofloxacin Fluoroquinolone
Okacin Lomefloxacin Fluoroquinolone
Omnicef Cefdinir Cephalosporin
Orbenin Cloxacillin Penicillin
Orelox Cefpodoxime proxetil Cephalosporin
Oribiox Oxolinic acid Quinolone
Oxistat Oxiconazole nitrate Antifungal
Ozex Tosufloxacin Fluoroquinolone
Paludrine Proguanil Antiparasitic
Paluther Artemether Antimalarial
Panmycin Tetracycline hydrochloride Tetracycline
Paser Aminosalicylic acid Antimycobacterial
Pasil Pazufloxacin Fluoroquinolone
Pathocil Dicloxacillin sodium Penicillin
Pazucross Pazufloxacin Fluoroquinolone
PCE Erythromycin Macrolide
Pediazole Erythromycin ethylsuccinate/sulfisoxazole Macrolide/sulfonamide
Peflacine Pefloxacin Fluoroquinolone
Peflox Pefloxacin Fluoroquinolone
Pegasys Peginterferon alfa-2a Antiviral
Pegetron Peginterferon alfa-2b/ribavirin Antiviral
PEG-Intron Peginterferon alfa-2b Antiviral
Penetrex Enoxacin Fluoroquinolone
Penglobe Bacampicillin Penicillin
Pentacarinat Pentamidine isethionate Antiprotozoal
Pentam Pentamidine isethionate Antiprotozoal
Pentostam Sodium stibogluconate Antiparasitic
Periostat Doxycycline Tetracycline
Permapen Penicillin G benzathine Penicillin
Pevisone Econazole Antifungal
Pfizerpen Penicillin G potassium Penicillin
Pfizerpen-AS Penicillin G procaine Penicillin
Pin-X Pyrantel pamoate Anthelmintic
Pipracil Piperacillin Penicillin
Pipril Piperacillin Penicillin
Plaquenil Sulfate Hydroxychloroquine sulfate Antimalarial
Plasmotrim Artesunate Antimalarial
Podomexef Cefpodoxime proxetil Cephalosporin
Polycillin Ampicillin trihydrate Penicillin
Polycillin-N Ampicillin sodium Penicillin
Polymox Amoxicillin Penicillin
Precef Ceforanide Cephalosporin
Prevpac Amoxicillin/clarithromycin/lansoprazole Anti-Helicobacter
Prezista Darunavir Antiretroviral
Priftin Rifapentine Antimycobacterial
Primaxin Imipenem, cilastatin Carbapenem
Primbactam Aztreonam Monobactam
Primsol Trimethoprim Folate antagonist
Probampacin Ampicillin/probenecid Penicillin/tubular secretion inhibitor
Procef Cefprozil Cephalosporin
Proloprim Trimethoprim Folate antagonist
Proquin XR Ciprofloxacin Fluoroquinolone
Protostat Metronidazole Nitroimidazole
Qualaquin Quinine sulfate Antimalarial
Quixin Levofloxacin Fluoroquinolone
Rebetol Ribavirin Antiviral
Rebetron Interferon alfa-2b recombinant/ribavirin Antiviral
Reese's Pinworm Medicine Pyrantel pamoate Anthelmintic
Relenza Zanamivir Antiviral
Rescriptor Delavirdine Antiretroviral
Retrovir Zidovudine Antiviral
Reyataz Atazanavir Protease inhibitor
Riamet Artemether/lumefantrine Antimalarial
Ribasphere Ribavirin Antiviral
Rifadin Rifampin Antimycobacterial
Rifamate Rifampin/isoniazid Antimycobacterial
Rifater Rifampin/pyrazinamide Antimycobacterial
Rifinah Rifampin/isoniazid Antimycobacterial
Rimactane Rifampin Antimycobacterial
Rimactane/INH Rifampin/isoniazid Antimycobacterial
Robimycin Erythromycin Macrolide
Robitet Tetracycline hydrochloride Tetracycline
Rocephalin Ceftriaxone Cephalosporin
Rocephin Ceftriaxone Cephalosporin
Rocephine Ceftriaxone Cephalosporin
Roferon-A Interferon alfa-2a recombinant Antiviral
Roflual Rimantadine Antiviral
Rondomycin Methacycline Tetracycline
Rovamycin Spiramycin Macrolide
Rovamycine Spiramycin Macrolide
Rozex Metronidazole Nitroimidazole
Rulid Roxithromycin Macrolide
Rulide Roxithromycin Macrolide
Securopen Azlocillin Penicillin
Selexid Pivmecillinam Penicillin
Selzentry Maraviroc Antiretroviral
Septra, Septra DS Trimethoprim/sulfamethoxazole Folate antagonists
Seromycin Cycloserine Antimycobacterial
Servambutol Ethambutol Antimycobacterial
Silvadene Silver sulfadiazine Sulfonamide
Spectazole Econazole nitrate Antifungal
Spectracef Cefditoren pivoxil Cephalosporin
Spectrobid Bacampicillin hydrochloride Penicillin
Sporanox Itraconazole Antifungal
Stocrin Efavirenz Antiretroviral
Storz-G Gentamicin sulfate Aminoglycoside
Stribild Elvitegravir/cobicistat/emtricitabine/tenofovir Antiretroviral
Stromectol Ivermectin Antiparasitic
Sulfamylon Mafenide Sulfonamide
Sulfatrim Trimethoprim/sulfamethoxazole Folate antagonists
Sulfoxaprim Trimethoprim/sulfamethoxazole Folate antagonists
Sulperazon Cefoperazone/sulbactam Cephalosporin/β-lactamase inhibitor
Sulperazone Cefoperazone/sulbactam Cephalosporin/β-lactamase inhibitor
Sultrin Triple Sulfa Sulfabenzamide/sulfacetamide/sulfathiazole Sulfonamide
Sumamed Azithromycin Azalide
Sumycin Tetracycline hydrochloride Tetracycline
Suprax Cefixime Cephalosporin
Surlid Roxithromycin Macrolide
Sustiva Efavirenz Antiretroviral
Symadine Amantadine hydrochloride Antiviral
Symmetrel Amantadine hydrochloride Antiviral
Synagis Palivizumab Antiviral
Synercid Quinupristin/dalfopristin Streptogramin
Tamiflu Oseltamivir Antiviral
Tao Troleandomycin Macrolide
Tarcil Ticarcillin disodium Penicillin
Targocid Teicoplanin Glycopeptide
Tarivid Ofloxacin Fluoroquinolone
Tavanic Levofloxacin Fluoroquinolone
Tazicef Ceftazidime Cephalosporin
Tazidime Ceftazidime Cephalosporin
Tazocin Piperacillin/tazobactam Penicillin/β-lactamase inhibitor
Teflaro Ceftaroline Cephalosporin
Telzir Fosamprenavir Antiretroviral
Terazol Terconazole Antifungal
Tetrachel Tetracycline hydrochloride Tetracycline
Tetralan Tetracycline hydrochloride Tetracycline
Thermazene Silver sulfadiazine Sulfonamide
Tienam Imipenem/cilastatin Carbapenem
Timentin Ticarcillin disodium/clavulanate potassium Penicillin/β-lactamase inhibitor
Tinactin Tolnaftate Antifungal
Tinaderm Tolnaftate Antifungal
Tindamax Tinidazole Antiparasitic
Tivicay Dolutegravir Antiretroviral
TOBI Tobramycin inhalation solution Aminoglycoside
TobraDex Tobramycin/dexamethasone Aminoglycoside/corticosteroid
Tobrex Tobramycin Aminoglycoside
Tosacin Tosufloxacin Fluoroquinolone
Totacillin Ampicillin trihydrate Penicillin
Totacillin-N Ampicillin sodium Penicillin
Trecator Ethionamide Antimycobacterial
Trimopan Trimethoprim Folate antagonist
Trimox Amoxicillin Penicillin
Trimpex Trimethoprim Folate antagonist
Triple Sulfa Sulfabenzamide/sulfacetamide/sulfathiazole Sulfonamide
Trizivir Abacavir/lamivudine/zidovudine Antiretroviral
Trobicin Spectinomycin hydrochloride Aminocyclitol
Truvada Emtricitabine/tenofovir Antiretroviral
Tygacil Tigecycline Glycylcycline
Tyzeka Telbivudine Antiviral
Ultracef Cefadroxil Cephalosporin
Unasyn Ampicillin/sulbactam Penicillin/β-lactamase inhibitor
Unipen Nafcillin sodium Penicillin
Uniquin Lomefloxacin Fluoroquinolone
Urex Methenamine hippurate Urinary anti-infective
Uri-Tet Oxytetracycline hydrochloride Tetracycline
Urobactam Aztreonam Monobactam
Urobiotic Oxytetracycline hydrochloride Tetracycline
Uroflox Rufloxacin Fluoroquinolone
Uroplus Trimethoprim/sulfamethoxazole Folate antagonists
Valcyte Valganciclovir Antiviral
Valtrex Valacyclovir Antiviral
Vancocin Vancomycin hydrochloride Glycopeptide
Vancoled Vancomycin hydrochloride Glycopeptide
Vancor Vancomycin hydrochloride Glycopeptide
Vantin Cefpodoxime proxetil Cephalosporin
Vectavir Penciclovir Antiviral
Vectrin Minocycline Tetracycline
Velosef Cephradine Cephalosporin
Vercef Cefaclor Cephalosporin
Versiclear Sodium thiosulfate Antifungal
VFend Voriconazole Antifungal
Vibativ Televancin Lipopeptide
Vibramycin Calcium Doxycycline calcium Tetracycline
Vibramycin Hyclate Doxycycline hyclate Tetracycline
Vibramycin Monohydrate Doxycycline monohydrate Tetracycline
Vibra-Tabs Doxycycline hyclate Tetracycline
Victrelis Boceprevir Antiviral (hepatitis C)
Videx Didanosine Antiretroviral
Videx EC Didanosine Antiretroviral
Vigamox Moxifloxacin Fluoroquinolone
Viracept Nelfinavir Protease inhibitor
Viraday Efavirenz/emtricitabine/tenofovir Antiretroviral
Vira-MP Vidarabine Antiviral
Viramune Nevirapine Antiretroviral
Virazole Ribavirin Antiviral
Viread Tenofovir Antiretroviral
Viroptic Trifluridine Antiviral
Vistide Cidofovir Antiviral
Vitrasert Ganciclovir Antiviral
Wellvone Atovaquone Antiparasitic
Wyamycin Erythromycin stearate Macrolide
Wycillin Penicillin G procaine Penicillin
Xifaxan Rifaximin Rifamycin
Xigris Drotrecogin alfa (activated) Antisepsis
Yodoxin Iodoquinol Amebicide
Yodoxin M Iodoquinol Amebicide
Yomesan Niclosamide Anthelmintic
Zagam Sparfloxacin Fluoroquinolone
Zazole Terconazole Antifungal
Zeclar Clarithromycin Macrolide
Zeffix Lamivudine Antiretroviral
Zeftera Ceftobiprole Cephalosporin
Zelitrex Valacyclovir Antiviral
Zentel Albendazole Antiparasitic
Zerit Stavudine (d4T) Antiretroviral
Ziagen Abacavir Antiretroviral
Ziagenavir Abacavir Antiretroviral
Zinacef Cefuroxime sodium Cephalosporin
Zinamide Pyrazinamide Antimycobacterial
Zinnat Cefuroxime axetil Cephalosporin
Zithromax Azithromycin Azalide
Zithromax Tri-Pak Azithromycin Azalide
Zitromax Azithromycin Azalide
Zmax Azithromycin Azalide
Zolicef Cefazolin sodium Cephalosporin
Zosyn Piperacillin/tazobactam Penicillin/β-lactamase inhibitor
Zovirax Acyclovir Antiviral
Z-PAK Azithromycin Azalide
Zymar Gatifloxacin Fluoroquinolone
Zyvox Linezolid Oxazolidinone
Zyvoxam Linezolid Oxazolidinone

Antimicrobial Spectrum, Dosing Information, Adverse Reaction

Antimicrobial Spectrum, Dosing Information, and Adverse Reaction Return to Top

Antibiotic Agent Antimicrobial Spectrum Dosing Information Notable Adverse Reaction
Amikacin
  • Escherichia coli
  • Klebsiella
  • Proteus
  • Enterobacter
  • Serratia
  • Pseudomonas
  • Neonates (postnatal age ≤ 7 days): 7.5 mg/kg q 12-18 hr IV or IM (≤ 2,000 g); 10 mg/kg q 12 hr IV or IM (> 2,000 g)
  • Neonates (postnatal age > 7 days): 7.5 mg/kg q 8-12 hr IV or IM (≤ 2,000 g); 10 mg/kg q 8 hr IV or IM (> 2,000 g)
  • Children: 15-25 mg/kg/24 hr divided q 8-12 hr IV or IM
  • Adults: 15 mg/kg 24 hr divided q 8-12 hr IV or IM
  • Ototoxicity
  • Nephrotoxicity
Amoxicillin
  • Gram-positive pathogens except Staphylococcus
  • Salmonella
  • Shigella
  • Neisseria
  • E. coli
  • Proteus mirabilis
  • Children: 20-50 mg/kg/24 hr divided q 8-12 hr PO. Higher dose of 80-90 mg/kg 24 hr PO for otitis media
  • Adults: 250-500 mg q 8-12 hr PO
  • Rash
  • Diarrhea
  • Cramping
Amoxicillin-Clavulanate
  • S. aureus, methicillin-susceptible
  • Streptococcus
  • Haemophilus influenzae
  • Moraxella catarrhalis
  • E. coli
  • Klebsiella
  • Bacteroides fragilis
  • Neonates: 30 mg/kg/24 hr divided q 12 hr PO.
  • Children: 20-45 mg/kg 24 hr divided q 8-12 hr PO. Higher dose 80-90 mg/kg/24 hr PO for otitis media.
  • Diarrhea
  • Rash
Ampicillin
  • Gram-positive pathogens except Staphylococcus
  • Salmonella
  • Shigella
  • Neisseria
  • E. coli
  • Proteus mirabilis
  • Neonates (postnatal age ≤ 7 days): 50 mg/kg/24 hr IV or IM q 12 hr (≤ 2,000 g); 75 mg/kg/24 hr divided q 8 hr IV or IM (> 2,000 g)
  • Neonates (postnatal age > 7 days): 50 mg/kg/24 hr IV or IM q 12 hr (< 1,200 g); 75 mg/kg/24 hr divided q 8 hr IV or IM (1,200–2,000 g); 100 mg/kg/24 hr divided q 6 hr IV or IM (> 2,000 g)
  • Children: 100-200 mg/kg/24 hr divided q 6 hr IV or IM
  • Adults: 250-500 mg q 4-8 hr IV or IM
  • Diarrhea
Ampicillin-Sulbactam
  • S. aureus
  • H. influenzae
  • M. catarrhalis
  • E. coli
  • Klebsiella
  • B. fragilis
  • Children: 100-200 mg/kg/24 hr divided q 4-8 hr IV or IM
  • Adults: 1-2 g q 6-8 hr IV or IM (max daily dose: 8 g)
  • Diarrhea
  • Rash
Azithromycin
  • S. aureus
  • Streptococcus
  • H. influenzae
  • Mycoplasma
  • Legionella
  • Chlamydia trachomatis
  • Children: 10 mg/kg PO on day 1 (max dose: 500 mg) followed by 5 mg/kg PO q 24 hr for 4 days.
  • Adults: 500 mg PO day 1 followed by 250 mg for 4 days.
  • Gastrointestinal distress
Aztreonam
  • Gram-negative aerobic bacteria
  • Enterobacteriaceae
  • Pseudomonas aeruginosa
  • Neonates (postnatal age ≤ 7 days): 60 mg/kg/24 hr divided q 12 hr IV or IM (≤ 2,000 g); 90 mg/kg/24 hr divided q 8 hr IV or IM (> 2,000 g)
  • Neonates (postnatal age > 7 days): 60 mg/kg/24 hr divided q 12 hr IV or IM (< 1,200 g); 90 mg/kg/24 hr divided q 8 hr IV or IM (1,200–2,000 g); 120 mg/kg/24 hr divided q 6-8 hr IV or IM (> 2,000 g)
  • Children: 90-120 mg/kg/24 hr divided q 6-8 hr IV or IM
  • Adults: 1-2 g IV or IM q 8-12 hr (max dose: 8 g/24 hr)
  • Rash
  • Thrombophlebitis
  • Eosinophilia
Carbenicillin
  • Enterobacter
  • Proteus
  • Pseudomonas
  • Neonates (postnatal age ≤ 7 days): 225 mg/kg/24 hr divided q 8 hr IV or IM (≤ 2,000 g); 300 mg/kg/24 hr divided q 6 hr IV or IM (> 2,000 g)
  • Neonates (postnatal age > 7 days): 300-400 mg/kg/24 hr divided q 6 hr IV or IM
  • Children: 400-600 mg/kg/24 hr divided q 4-6 hr IV or IM
  • Rash
  • Liver transaminases elevation
Cefaclor
  • S. aureus
  • S. pneumoniae
  • H. influenzae
  • E. coli
  • Klebsiella
  • Proteus
  • Children: 20-40 mg/kg/24 hr divided q 8-12 hr PO (max dose: 2 g)
  • Adults: 250-500 mg q 6-8 hr PO
  • Rash
  • Eosinophilia
  • Serum sickness-like reaction
Cefadroxil
  • S. aureus
  • Streptococcus
  • E. coli
  • Klebsiella
  • Proteus
  • Children: 30 mg/kg/24 hr divided q 12 hr PO (max dose: 2 g)
  • Adults: 250-500 mg q 8-12 hr PO
  • Rash
  • Eosinophilia
Cefazolin
  • S. aureus
  • Streptococcus
  • E. coli
  • Klebsiella
  • Proteus
  • Neonates (postnatal age ≤ 7 days): 40 mg/kg/24 hr divided q 12 hr IV or IM
  • Neonates (postnatal age > 7 days): 40-60 mg/kg/24 hr divided q 8 hr IV or IM
  • Children: 50-100 mg/kg/24 hr divided q 8 hr IV or IM
  • Adults: 0.5-2g q 8 hr IV or IM (max dose: 12 g/24 hr)
  • Rash
  • Eosinophilia
Cefdinir
  • Extended-spectrum cephalosporin
  • Children: 14 mg/kg/24 hr in 1 or 2 doses PO (max dose: 600 mg/24 hr)
  • Adults: 600 mg q 24 hr PO
  • Diarrhea
Cefepime
  • Gram-positive bacteria
  • Gram-negative bacteria including P. aeruginosa
  • Children: 100-150 mg/kg/24 hr q 8-12 hr IV or IM
  • Adults: 2-4 g/24 hr q 12 hr IV or IM
  • Diarrhea
  • Nausea
  • Vaginal candidiasis
  • Rash
  • Eosinophilia
Cefixime
  • Streptococci
  • H. influenzae
  • M. catarrhalis
  • Neisseria gonorrhoeae
  • Serratia marcescens
  • P. vulgaris
  • Children: 8 mg/kg/24 hr divided q 12-24 hr PO
  • Adults: 400 mg/24 hr divided q 12-24 hr PO
  • Rash
  • Eosinophilia
Cefoperazone
  • Gram-positive pathogens
  • Gram-negative pathogens
  • Neonates: 100 mg/kg/24 hr divided q 12 hr IV or IM
  • Children: 100-150 mg/kg/24 hr divided q 8-12 hr IV or IM
  • Adults: 2-4 g/24 hr divided q 8-12 hr IV or IM (max dose: 12 g/24 hr)
  • Hypoprothrombinemia
  • Disulfiram-life reaction
Cefotaxime
  • Gram-positive pathogens
  • Gram-negative pathogens
  • Neonates (postnatal age ≤ 7 days): 100 mg/kg/24 hr divided q 12 hr IV or IM
  • Neonates (postnatal age > 7 days): 100 mg/kg/24 hr divided q 12 hr IV or IM (< 1,200 g); 150 mg/kg/24 hr divided q 8 hr IV or IM (> 1,200 g)
  • Children: 150 mg/kg/24 hr divided q 6-8 hr IV or IM
  • Adults: 1-2 g q 8-12 hr IV or IM (max dose: 12 g/24 hr)
  • Rash
  • Eosinophilia
Cefotetan
  • S. aureus
  • Streptococcus
  • H. influenzae
  • E. coli
  • Klebsiella
  • Proteus
  • Bacteroides
  • Children: 40-80 mg/kg/24 hr divided IV or IM q 12 hr
  • Adults: 2-4 g/24 hr divided q 12 hr IV or IM (max dose: 6 g/24 hr)
  • Rash
  • Eosinophilia
  • Hypoprothrombinemia
  • Disulfiram-life reaction
Cefoxitin
  • S. aureus
  • Streptococcus
  • H. influenzae
  • E. coli
  • Klebsiella
  • Proteus
  • Bacteroides
  • Neonates: 70-100 mg/kg/24 hr divided q 8-12 hr IV or IM
  • Children: 80-160 mg/kg/24 hr divided q 6-8 hr IV or IM
  • Adults: 1-2 g q 6-8 hr IV or IM (max dose: 12 g/24 hr)
  • Rash
  • Eosinophilia
Cefpodoxime
  • S. aureus
  • Streptococcus
  • H. influenzae
  • M. catarrhalis
  • N. gonorrhoeae
  • E. coli
  • Klebsiella
  • Proteus
  • Children: 10 mg/kg/24 hr divided q 12 hr PO
  • Adults: 200-800 mg/24 hr divided q 12 hr PO (max dose: 800 mg/24 hr)
  • Rash
  • Eosinophilia
Cefprozil
  • S. aureus
  • Streptococcus
  • H. influenzae
  • E. coli
  • M. catarrhalis
  • Klebsiella
  • Proteus
  • Children: 30 mg/kg/24 hr divided q 8-12 hr PO
  • Adults: 500-1,000 mg/24 hr divided q 12 hr PO (max dose: 1.5 g/24 hr)
  • Rash
  • Eosinophilia
Ceftazidime
  • Gram-positive pathogens
  • Gram-negative pathogens including P. aeruginosa
  • Neonates (postnatal age ≤ 7 days): 100 mg/kg/24 hr divided q 12 hr IV or IM
  • Neonates (postnatal age > 7 days): 100 mg/kg/24 hr divided q 12 hr IV or IM (< 1,200 g); 150 mg/kg/24 hr divided q 8 hr IV or IM (> 1,200 g)
  • Children: 150 mg/kg/24 hr divided q 8 hr IV or IM
  • Adults: 1-2 g q 8-12 hr IV or IM (max dose: 8-12 g/24 hr)
  • Rash
  • Eosinophilia
Ceftiaoxime
  • Gram-positive pathogens
  • Gram-negative pathogens
  • Children: 150 mg/kg/24 hr divided q 6-8 hr IV or IM
  • Adults: 1-2 g q 6-8 hr IV or IM (max dose: 12 g/24 hr)
  • Rash
  • Eosinophilia
Ceftriaxone
  • Gram-positive pathogens
  • Gram-negative pathogens
  • Neonates: 50-75 mg/kg q 24 hr IV or IM
  • Children: 50-75 mg/kg q 24 hr IV or IM
  • Adults: 1-2 g q 24 hr IV or IM (max dose: 4 g/24 hr)
  • Rash
  • Eosinophilia
Cefuroxime
  • S. aureus
  • Streptococcus
  • H. influenzae
  • E. coli
  • M. catarrhalis
  • Klebsiella
  • Proteus
  • Neonates: 40-100 mg/kg/24 hr divided q 12 hr IV or IM
  • Children: 200-240 mg/kg/24 hr divided q 8 hr IV or IM; 20-30 mg/kg/24 hr divided q 8 hr PO
  • Adults: 750-1,500 mg q 8 hr IV or IM (max dose: 6 g/24 hr)
  • Rash
  • Eosinophilia
Cephalexin
  • S. aureus
  • Streptococcus
  • E. coli
  • Klebsiella
  • Proteus
  • Children: 25-100 mg/kg/24 hr divided q 6-8 hr PO
  • Adults: 250-500 mg q 6 hr PO (max dose: 4 g/24 hr)
  • Rash
  • Eosinophilia
Cephradine
  • S. aureus
  • Streptococcus
  • E. coli
  • Klebsiella
  • Proteus
  • Children: 50-100 mg/kg/24 hr divided q 6-12 hr PO
  • Adults: 250-500 mg q 6-12 hr PO (max dose: 4 g/24 hr)
  • Rash
  • Eosinophilia
Chloramphenicol
  • Gram-positive pathogens
  • Salmonella
  • Enterococcus faecium
  • Bacteroides
  • Mycoplasma
  • Chlamydia
  • Rickettsia
  • Neonates: loading dose of 20 mg/kg followed by
  • Neonates (postnatal age ≤ 7 days): 25 mg/kg/24 hr q 24 hr IV
  • Neonates (postnatal age > 7 days): 25 mg/kg/24 hr q 24 hr IV (< 2,000 g); 50 mg/kg/24 hr divided q 12 hr IV (> 2,000 g)
  • Children: 50-75 mg/kg/24 hr divided q 6-8 hr IV or PO
  • Adults: 50 mg/kg/24 hr divided q 6 hr IV or PO (max dose: 4 g/24 hr)
  • Gray-baby syndrome
  • Bone marrow suppression
  • Aplastic anemia
Ciprofloxacin
  • P. aeruginosa
  • Serratia
  • Enterobacter
  • Shigella
  • Salmonella
  • Campylobacter
  • N. gonorrhoeae
  • H. influenzae
  • M. catarrhalis
  • Neonates: 10 mg/kg q 12 hr PO or IV
  • Children: 15-30 mg/kg/24 hr divided q 12 hr PO or IV
  • Adults: 250-750 mg q 12 hr; 200-400 mg IV q 12 hr PO (max dose: 1.5 g/24 hr)
  • Tendonitis
  • Dizziness
  • Confusion
  • Crystalluria
  • Photosensitivity
Clarithromycin
  • S. aureus
  • Streptococcus
  • H. influenzae
  • Legionella
  • Mycoplasma
  • C. trachomatis
  • Children: 15 mg/kg/24 hr divided q 12 hr PO
  • Adults: 250-500 mg q 12 hr PO (max dose: 1 g/24 hr)
  • Gastrointestinal distress
  • Dyspepsia
  • Nausea
  • Cramping
Clindamycin
  • Gram-positive aerobic pathogens
  • Anaerobic cocci except Enterococcus
  • Neonates (postnatal age ≤ 7 days): 10 mg/kg/24 hr divided q 12 hr IV or IM (≤ 2,000 g); 15 mg/kg/24 hr divided q 8 hr IV or IM (> 2,000 g)
  • Neonates (postnatal age > 7 days): 10 mg/kg/24 hr IV or IM divided q 12 hr (≤ 1,200 g); 15 mg/kg/24 hr divided q 8 hr IV or IM (1,200–2,000 g); 20 mg/kg/24 hr divided q 8 hr IV or IM (> 2,000 g)
  • Children: 10-40 mg/kg/24 hr divided q 6-8 hr IV, IM, or PO
  • Adults: 150-600 mg q 6-8 hr IV, IM, or PO (max dose: 5 g/24 hr IV or IM or 2 g/24 hr PO)
  • Diarrhea
  • Nausea
  • Pseudomembranous colitis
  • Rash
Cloxacillin
  • S. aureus and other gram-positive cocci except Enterococcus and coagulase-negative staphylococci
  • Children: 50-100 mg/kg/24 hr divided q 6 hr PO
  • Adults: 250-500 mg q 6 hr PO (max dose: 4 g/24 hr)
  • Rash
  • Eosinophilia
Trimethoprim-Sulfamethoxazole
  • Shigella
  • Legionella
  • Nocardia
  • Chlamydia
  • Pneumocystis jirovecii
  • Children: 6-20 mg TMP/kg/24 hr or IV divided q 12 hr PO
  • Adults: 160 mg TMP q 12 hr PO
  • Rash
  • Erythema multiforme
  • Stevens-Johnson syndrome
  • Nausea
  • Leukopenia
Demeclocycline
  • Gram-positive cocci except Enterococcus
  • Gram-negative bacilli
  • Anaerobes
  • Borrelia burgdorferi
  • Mycoplasma
  • Chlamydia
  • Children: 8-12 mg/kg/24 hr divided q 6-12 hr PO
  • Adults: 150 mg PO q 6-8 hr
  • Teeth staining
  • Photosensitivity
  • Diabetes insipidus
  • Nausea
  • Vomiting
  • Diarrhea
Dicloxacillin
  • S. aureus and other gram-positive cocci except Enterococcus and coagulase-negative staphylococci
  • Children: 12.5-100 mg/kg/24 hr divided q 6 hr PO
  • Adults: 125-500 mg q 6 hr PO
  • Rash
  • Eosinophilia
Doripenem
  • Gram-positive cocci
  • Gram-negative bacilli including P. aeruginosa
  • Anaerobes
  • Adults: 500 mg q 8 hr IV
  • Rash
  • Eosinophilia
Doxycycline
  • Gram-positive cocci except Enterococcus
  • Gram-negative bacilli
  • Anaerobes
  • B. burgdorferi
  • Mycoplasma
  • Chlamydia
  • Children: 2-5 mg/kg/24 hr divided q 12-24 hr PO or IV (max dose: 200 mg/24 hr)
  • Adults: 100-200 mg/24 hr divided q 12-24 hr PO or IV
  • Teeth staining
  • Photosensitivity
  • Nausea
  • Vomiting
  • Diarrhea
Erythromycin
  • Gram-positive organisms
  • Corynebacterium diphtheriae
  • Mycoplasma pneumoniae
  • Neonates (postnatal age ≤ 7 days): 20 mg/kg/24 hr divided q 12 hr PO
  • Neonates (postnatal age > 7 days): 20 mg/kg/24 hr divided q 12 hr PO (< 1,200 g); 30 mg/kg/24 hr divided q 8 hr PO (> 1,200 g)
  • Children: Usual max dose 2 g/24 hr. Base: 30-50 mg/kg/24 hr divided q 6-8 hr PO. Estolate: 30-50 mg/kg/24 hr divided q 8-12 hr PO. Stearate: 20-40 mg/kg/24 hr divided q 6 hr PO. Lactobionate: 20-40 mg/kg/24 hr divided q 6-8 hr IV. Gluceptate: 20-50 mg/kg/24 hr divided q 6 hr IV; usual max dose 4 g/24 hr IV
  • Adults: Base: 333 mg PO q 8 hr; estolate/stearate/base: 250-500 mg q 6 hr PO
  • Cramping
  • Nausea
  • Vomiting
  • Diarrhea
  • Hypertrophic pyloric stenosis
Gentamicin
  • E. coli
  • Klebsiella
  • Proteus
  • Enterobacter
  • Serratia
  • Pseudomonas
  • Neonates (postnatal age ≤ 7 days): 2.5 mg/kg q 12-18 hr IV or IM (< 2,000 g); 2.5 mg/kg q 12 hr IV or IM (> 2,000 g)
  • Neonates (postnatal age > 7 days): 2.5 mg/kg q 8-12 hr IV or IM (< 2,000 g); 32.5 mg/kg q 8 hr IV or IM (> 2,000 g)
  • Children: 2.5 mg/kg/24 hr divided q 8-12 hr IV or IM; 5-7.5 mg/kg/24 hr IV once daily
  • Adults: 3-6 mg/kg/24 hr divided q 8 hr IV or IM
  • Ototoxicity
  • Nephrotoxicity
Imipenem-Cilastatin
  • Gram-positive cocci
  • Gram-negative bacilli including P. aeruginosa
  • Anaerobes
  • Neonates (postnatal age ≤ 7 days): 20 mg/kg q 18-24 hr IV or IM (< 1,200 g); 40 mg/kg divided q 12 hr IV or IM (> 1,200 g)
  • Neonates (postnatal age > 7 days): 40 mg/kg q 12 hr IV or IM (< 2,000 g); 60 mg/kg q 8 hr IV or IM (> 2,000 g)
  • Children: 60-100 mg/kg/24 hr divided q 6-8 hr IV or IM
  • Adults: 2-4 g/24 hr divided q 6-8 hr IV or IM (max dose: 4 g/24 hr)
  • Rash
  • Eosinophilia
  • Nausea
  • Seizures
Linezolid
  • Staphylococcus
  • Streptococcus
  • E. faecium
  • Enterococcus faecalis
  • Children: 10 mg/kg q 12 hr IV or PO
  • Adults: Pneumonia: 600 mg q 12 hr IV or PO
  • Bone marrow suppression
  • Pseudomembranous colitis
  • Nausea
  • Diarrhea
  • Headache
Loracarbef
  • S. aureus
  • Streptococcus
  • H. influenzae
  • M. catarrhalis
  • E. coli
  • Klebsiella
  • Proteus
  • Children: 30 mg/kg/24 hr divided q 12 hr PO (max dose: 2 g)
  • Adults: 200-400 mg q 12 hr PO (max dose: 800 mg/24 hr)
  • Rash
  • Eosinophilia
Meropenem
  • Gram-positive cocci
  • Gram-negative bacilli including P. aeruginosa
  • Anaerobes
  • Children: 60 mg/kg/24 hr divided q 8 hr IV
  • Adults: 1.5-3 g q 8 hr IV
  • Rash
  • Eosinophilia
Metronidazole
  • Anaerobes
  • Neonates (postnatal age ≤ 7 days): 7.5 mg/kg 48 hr PO or IV (< 1,200 g); 7.5 mg/kg/24 hr q 24 hr PO or IV (1,200–2,000 g); 15 mg/kg/24 hr divided q 12 hr PO or IV (> 2,000 g)
  • Neonates (postnatal age > 7 days): 5 mg/kg/24 hr divided q 12 hr PO or IV (< 2,000 g); 30 mg/kg/24 hr divided q 12 hr PO or IV (> 2,000 g)
  • Children: 30 mg/kg/24 hr divided q 6-8 hr PO or IV
  • Adults: 30 mg/kg/24 hr divided q 6 hr PO or IV (max dose: 4 g/24 hr)
  • Dizziness
  • Seizures
  • Metallic taste
  • Nausea
  • Hypoprothrombinemia
  • Disulfiram-like reaction
Mezlocillin
  • E. coli
  • Enterobacter
  • Serratia
  • Bacteroides
  • Neonates (postnatal age ≤ 7 days): 150 mg/kg/24 hr divided q 12 hr IV
  • Neonates (postnatal age > 7 days): 225 mg/kg divided q 8 hr IV
  • Children: 200-300 mg/kg/24 hr divided q 4-6 hr IV
  • Adults: 2-4 g/dose q 4-6 hr IV (max dose: 12 g/24 hr)
  • Rash
  • Eosinophilia
  • Liver transaminases elevation
Mupirocin
  • Staphylococcus
  • Streptococcus
  • Topical application to the skin 2-4 times per day
  • Itching
Nafcillin
  • S. aureus and other gram-positive cocci except Enterococcus and coagulase-negative staphylococci
  • Neonates (postnatal age ≤ 7 days): 50 mg/kg/24 hr divided q 12 hr IV or IM (< 2,000 g); 75 mg/kg/24 hr divided q 8 hr IV or IM (> 2,000 g)
  • Neonates (postnatal age > 7 days): 75 mg/kg/q 8 hr IV (< 2,000 g); 100 mg/kg divided q 6-8 hr IV (> 2,000 g)
  • Children: 100-200 mg/kg/24 hr divided q 4-6 hr IV
  • Adults: 4-12 g/24 hr divided q 4-6 hr IV (max dose: 12 g/24 hr)
  • Rash
  • Eosinophilia
  • Phlebitis
  • Neutropenia
Nalidixic acid
  • E. coli
  • Enterobacter
  • Klebsiella
  • Proteus
  • Children: 50-55 mg/kg/24 hr divided q 6 hr PO; suppressive therapy 25-33 mg/kg/24 hr divided q 6-8 hr PO
  • Adults: 1 g q 6 hr PO; suppressive therapy: 500 mg q 6 hr PO
  • Vertigo
  • Dizziness
  • Rash
Neomycin
  • Gastrointestinal flora
  • Infants: 50 mg/kg/24 hr divided q 6 hr PO
  • Children: 50-100 mg/kg/24 hr divided q 6-8 hr PO
  • Adults: 500-2,000 mg/dose q 6-8 hr PO
  • Cramping
  • Diarrhea
  • Rash
  • Ototoxicity
  • Nephrotoxicity
Nitrofurantoin
  • Gram-positive pathogens
  • Gram-negative pathogens
  • Children: 5-7 mg/kg/24 hr divided q 6 hr PO (max dose: 400 mg/24 hr); suppressive therapy 1-2.5 mg/kg/24 hr divided q 12-24 hr PO (max dose: 100 mg/24 hr)
  • Adults: 50-100 mg/24 hr divided q 6 hr PO
  • Vertigo
  • Dizziness
  • Rash
  • Jaundice
  • Interstitial pneumonitis
Ofloxacin
  • Gram-positive pathogens
  • Gram-negative pathogens
  • Anaerobes
  • Chlamydia trachomatis
  • Child (< 12 yr): Conjunctivitis: 1-2 drops in affected eye(s) q 2-4 hr for 2 days, then 1-2 drops qid for 5 days. Corneal ulcers: 1-2 drops q 30 min while awake and at 4 hours at night for 2 days, then 1-2 drops hourly for 5 days while awake, then 1-2 drops q 6 hr for 2 days. Otitis externa: 5 drops into affected ear bid for 10 days
  • Child (> 12 yr) and adults: Ophthalmic solution doses same as for younger children. Otitis externa: 10 drops bid for 10–14 days as for younger children
  • Burning
  • Stinging
  • Eye redness
  • Dizziness
Oxacillin
  • S. aureus and other gram-positive cocci except Enterococcus and coagulase-negative staphylococci
  • Neonates (postnatal age ≤ 7 days): 50 mg/kg/24 hr divided q 12 hr IV (< 2,000 g); 75 mg/kg/24 hr IV divided q 8 hr IV (> 2,000 g)
  • Neonates (postnatal age > 7 days): 50 mg/kg/24 hr IV divided q 12 hr IV (< 1,200 g); 75 mg/kg/24 hr divided q 8 hr IV (1,200–2,000 g); 100 mg/kg/24 hr IV divided q 6 hr IV (> 2,000 g)
  • Infants: 100-200 mg/kg/24 hr divided q 4-6 hr IV
  • Children: PO 50-100 mg/kg/24 hr divided q 4-6 hr IV
  • Adults: 2-12 g/24 hr divided q 4-6 hr IV (max dose: 12 g/24 hr)
  • Rash
  • Eosinophilia
  • Neutropenia
Penicillin G
  • S. pneumoniae
  • Group A Streptococcus
  • N. gonorrhoeae
  • N. meningitidis
  • Neonates (postnatal age ≤ 7 days): 50,000 units/kg/24 hr divided q 12 hr IV or IM (< 2,000 g); 75,000 units/kg/24 hr divided q 8 hr IV or IM (> 2,000 g)
  • Neonates (postnatal age > 7 days): 50,000 units/kg/24 hr divided q 12 hr IV (< 1,200 g); 75,000 units/kg/24 hr q 8 hr IV (1,200–2,000 g); 100,000 units/kg/24 hr divided q 6 hr IV (> 2,000 g)
  • Children: 100,000-250,000 units/kg/24 hr divided q 4-6 hr IV or IM (max dose: 400,000 units/kg/24 hr)
  • Adults: 2-24 million units/24 hr divided q 4-6 hr IV or IM
  • Rash
  • Eosinophilia
  • Allergy
  • Seizures
Penicillin G, benzathine
  • Group A Streptococcus
  • Neonates: 50,000 units/kg IM once
  • Children: 300,000-1.2 million units/kg q 3-4 wk IM (max dose: 1.2-2.4 million units/dose)
  • Adults: 1.2 million units IM q 3-4 wk
  • Rash
  • Eosinophilia
  • Allergy
Penicillin G, procaine
  • Gram-positive pathogens
  • Neonates: 50,000 units/kg/24 hr IM
  • Children: 25,000-50,000 units/kg/24 hr IM for 10 days (max dose: 4.8 million units/dose)
  • Adults: 0.6-4.8 million units q 12-24 hr IM
  • Rash
  • Eosinophilia
  • Allergy
Penicillin V
  • S. pneumoniae
  • N. gonorrhoeae
  • N. meningitidis
  • Children: 25-50 mg/kg/24 hr divided q 4-8 hr PO
  • Adults: 125-500 mg q 6-8 hr PO (max dose: 3 g/24 hr)
  • Rash
  • Eosinophilia
  • Allergy
Piperacillin
  • E. coli
  • Enterobacter
  • Serratia
  • P. aeruginosa
  • Bacteroides
  • Neonates (postnatal age ≤ 7 days): 150 mg/kg/24 hr divided q 8-12 hr IV
  • Neonates (postnatal age > 7 days): 200 mg/kg divided q 6-8 hr IV
  • Children: 200-300 mg/kg/24 hr divided q 4-6 hr IV
  • Adults: 2-4 g/dose q 4-6 hr (max dose: 24 g/24 hr) IV
  • Rash
  • Eosinophilia
  • Serum sickness-like reaction
Piperacillin-Tazobactam
  • S. aureus
  • H. influenzae
  • E. coli
  • Enterobacter
  • Serratia
  • Acinetobacter
  • P. aeruginosa
  • Bacteroides
  • Children: 300-400 mg/kg/24 hr divided q 6-8 hr IV or IM
  • Adults: 3.375 g q 6-8 hr IV or IM
  • Rash
  • Eosinophilia
Quinupristin-Dalfopristin
  • E. faecium, vancomycin-resistant
  • S. aureus, methicillin-resistant
  • Children and adults: 7.5 mg/kg q 8 hr IV
  • Pain
  • Edema
  • Phlebitis
  • Nausea
  • Diarrhea
Sulfadiazine
  • E. coli
  • P. mirabilis
  • Klebsiella
  • Neonates: 100 mg/kg/24 hr divided q 12 hr PO with pyrimethamine 1 mg/kg/24 hr PO with folinic acid
  • Children: 120-200 mg/kg/24 hr divided q 6 hr PO with pyrimethamine 2 mg/kg/24 hr divided q 12 hr PO ≥3 days then 1 mg/kg/24 hr (max dose: 25 mg/24 hr) with folinic acid
  • Rash
  • Stevens-Johnson syndrome
  • Nausea
  • Leukopenia
  • Crystalluria
Sulfamethoxazole
  • Bacteria associated with otitis media, chronic bronchitis, and lower urinary tract infections
  • Children: 50-60 mg/kg/24 hr divided q 12 hr PO
  • Adults: 1 g/dose q 12 hr PO (max dose: 3 g/24 hr)
  • Rash
  • Stevens-Johnson syndrome
  • Nausea
  • Leukopenia
  • Crystalluria
Sulfisoxazole
  • Bacteria associated with otitis media, chronic bronchitis, and lower urinary tract infections
  • Children: 120-150 mg/kg/24 hr divided q 4-6 hr PO (max dose: 6 g/24 hr)
  • Adults: 4-8 g/24 hr divided q 4-6 hr PO
  • Rash
  • Stevens-Johnson syndrome
  • Nausea
  • Leukopenia
  • Crystalluria
Ticarcillin
  • E. coli
  • Enterobacter
  • Serratia
  • P. aeruginosa
  • Bacteroides
  • Neonates (postnatal age ≤ 7 days): 150 mg/kg/24 hr divided q 8-12 hr IV
  • Neonates (postnatal age > 7 days): 150 mg/kg/24 hr divided q 8-12 hr IV (< 1,200 g); 150 mg/kg/24 hr divided q 12 hr IV (1,200–2,000 g); 300 mg/kg/24 hr divided q 6-8 hr IV (> 2,000 g)
  • Children: 200-400 mg/kg/24 hr divided q 4-6 hr IV
  • Adults: 2-4 g/dose q 4-6 hr IV (max dose: 24 g/24 hr)
  • Rash
  • Eosinophilia
  • Liver transaminases elevation
Ticarcillin-Clavulanate
  • S. aureus
  • H. influenzae
  • Enterobacter
  • E. coli
  • Serratia
  • P. aeruginosa
  • Acinetobacter
  • Bacteroides
  • Children: 280-400 mg/kg/24 hr q 4-8 hr IV or IM
  • Adults: 3.1 g q 4-8 hr IV or IM (max dose: 18-24 g/24 hr)
  • Rash
  • Eosinophilia
  • Liver transaminases elevation
Tigecycline
  • Enterobacteriaceae including ESBL producers
  • Streptococcus
  • Staphylococcus
  • Anaerobes
  • Adults: 100 mg loading dose followed by 50 mg q 12 hr IV
  • Photosensitivity
  • Hypersensitivity
  • Hepatic impairment
Tobramycin
  • E. coli
  • Klebsiella
  • Enterobacter
  • Serratia
  • Proteus
  • Pseudomonas
  • Neonates (postnatal age ≤ 7 days): 2.5 mg/kg q12-18 hr IV or IM (< 2,000 g); 2.5 mg/kg q 12 hr IV or IM (> 2,000 g)
  • Neonates (postnatal age > 7 days): 2.5 mg/kg q 8-12 hr IV or IM (< 2,000 g); 2.5 mg/kg q 8 hr IV or IM (> 2,000 g)
  • Children: 2.5 mg/kg/24 hr divided q 8-12 hr IV or IM; 5-7.5 mg/kg/24 hr IV
  • Adults: 3-6 mg/kg/24 hr divided q 8 hr IV or IM
  • Ototoxicity
  • Nephrotoxicity
Trimethoprim
  • E. coli
  • Klebsiella
  • P. mirabilis
  • Enterobacter
  • P. jirovecii
  • Children (< 12 yr): 4-6 mg/kg/24 hr divided q 12 hr PO
  • Children (> 12 yr) and adults: 100-200 mg q 12 hr PO
  • Megaloblastic anemia
  • Bone marrow suppression
  • Nausea
  • Epigastric distress
  • Rash
Vancomycin
  • Gram-positive pathogens including Staphylococcus, S. pneumoniae, and Enterococcus
  • C. difficile
  • Neonates (postnatal age > 7 days): 15 mg/kg/24 hr divided q 24 hr IV (< 1,200 g); 15 mg/kg/24 hr divided q 12-18 hr IV (1,200–2,000 g); 30 mg/kg/24 hr divided q 12 hr IV (> 2,000 g)
  • Neonates (postnatal age > 7 days): 15 mg/kg/24 hr divided q 24 hr IV (< 1,200 g); 15 mg/kg/24 hr divided q 8-12 hr IV (1,200–2,000 g); 45 mg/kg/24 hr divided q 8 hr IV (> 2,000 g)
  • Children: 45-60 mg/kg/24 hr divided q 8-12 hr IV
  • C. difficile–associated colitis: 40-50 mg/kg/24 hr divided q 6-8 hr PO; 40-50 mg/kg/24 hr divided q 6-8 hr PO
  • Ototoxicity
  • Nephrotoxicity

Risk Categories of Antimicrobial Agents in Pregnancy

Risk Categories of Antibacterial Agents in Pregnancy Return to Top

Antimicrobial Agent Pregnancy Category Drug Class
Penicillins B Antibacterial agents
Beta lactam/Beta lactam inhibitor B Antibacterial agents
Cephalosporins B Antibacterial agents
Aztreonam B Antibacterial agents
Meropenem B Antibacterial agents
Ertapenem B Antibacterial agents
Doripenem B Antibacterial agents
Clindamycin B Antibacterial agents
Daptomycin B Antibacterial agents
Fosfomycin B Antibacterial agents
Erythromycin B Antibacterial agents
Azithromycin B Antibacterial agents
Metronidazole B Antibacterial agents
Nitrofurantoin B Antibacterial agents
Imipenem/Cilastatin C Antibacterial agents
Chloramphenicol C Antibacterial agents
Ciprofloxacin C Antibacterial agents
Ofloxacin C Antibacterial agents
Levofloxacin C Antibacterial agents
Gatifloxacin C Antibacterial agents
Gemifloxacin C Antibacterial agents
Moxifloxacin C Antibacterial agents
Colistin C Antibacterial agents
Linezolid C Antibacterial agents
Clarithromycin C Antibacterial agents
Rifaximin C Antibacterial agents
Sulfonamides/Trimethoprim C Antibacterial agents
Telavancin C Antibacterial agents
Telithromycin C Antibacterial agents
Tinidazole C Antibacterial agents
Vancomycin C Antibacterial agents
Amikacin D Antibacterial agents
Gentamicin D Antibacterial agents
Isepamicin D Antibacterial agents
Netilmicin D Antibacterial agents
Streptomycin D Antibacterial agents
Tobramycin D Antibacterial agents
Tetracyclines D Antibacterial agents
Tigecycline D Antibacterial agents

Risk Categories of Antimycobacterial Agents in Pregnancy Return to Top

Antimicrobial Agent Pregnancy Category Drug Class
Rifabutin B Antimycobacterial agents
Capreomycin C Antimycobacterial agents
Dapsone C Antimycobacterial agents
Isoniazid C Antimycobacterial agents
Pyrazinamide C Antimycobacterial agents
Rifampin C Antimycobacterial agents
Quinine X Antimycobacterial agents
Thalidomide X Antimycobacterial agents

Risk Categories of Antifungal Agents in Pregnancy Return to Top

Antimicrobial Agent Pregnancy Category Drug Class
Amphotericin B B Antifungal agents
Anidulafungin C Antifungal agents
Caspofungin C Antifungal agents
Fluconazole C Antifungal agents
Itraconazole C Antifungal agents
Ketoconazole C Antifungal agents
Flucytosine C Antifungal agents
Micafungin C Antifungal agents
Posaconazole C Antifungal agents
Terbinafine B Antifungal agents
Voriconazole D Antifungal agents

Risk Categories of Antiparasitic Agents in Pregnancy Return to Top

Antimicrobial Agent Pregnancy Category Drug Class
Nitazoxanide B Antiparasitic agents
Praziquantel B Antiparasitic agents
Albendazole C Antiparasitic agents
Mebendazole C Antiparasitic agents
Artemether C Antiparasitic agents
Lumefantrine C Antiparasitic agents
Atovaquone C Antiparasitic agents
Proguanil C Antiparasitic agents
Chloroquine C Antiparasitic agents
Eflornithine C Antiparasitic agents
Ivermectin C Antiparasitic agents
Mefloquine C Antiparasitic agents
Pentamidine C Antiparasitic agents
Pyrimethamine C Antiparasitic agents
Quinidine C Antiparasitic agents
Miltefosine X Antiparasitic agents

Risk Categories of Antiviral Agents in Pregnancy Return to Top

Antimicrobial Agent Pregnancy Category Drug Class
Acyclovir B Antiviral agents
Atazanavir B Antiviral agents
Darunavir B Antiviral agents
Didanosine B Antiviral agents
Emtricitabine B Antiviral agents
Enfuvirtide B Antiviral agents
Etravirine B Antiviral agents
Famciclovir B Antiviral agents
Maraviroc B Antiviral agents
Nelfinavir B Antiviral agents
Ritonavir B Antiviral agents
Saquinavir B Antiviral agents
Telbivudine B Antiviral agents
Tenofovir B Antiviral agents
Valacyclovir B Antiviral agents
Abacavir C Antiviral agents
Adefovir C Antiviral agents
Amantadine C Antiviral agents
Cidofovir C Antiviral agents
Delavirdine C Antiviral agents
Entecavir C Antiviral agents
Fosamprenavir C Antiviral agents
Foscarnet C Antiviral agents
Ganciclovir C Antiviral agents
Indinavir C Antiviral agents
Interferons C Antiviral agents
Lamivudine C Antiviral agents
Lopinavir C Antiviral agents
Ritonavir C Antiviral agents
Nevirapine C Antiviral agents
Oseltamivir C Antiviral agents
Raltegravir C Antiviral agents
Rimantadine C Antiviral agents
Stavudine C Antiviral agents
Tipranavir C Antiviral agents
Valganciclovir C Antiviral agents
Zalcitabine C Antiviral agents
Zanamivir C Antiviral agents
Zidovudine C Antiviral agents
Efavirenz D Antiviral agents
Ribavirin X Antiviral agents

FDA Pregnancy Categories Return to Top

Category Definition
A Adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in the first trimester of pregnancy
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women
C Animal reproduction studies have shown an adverse effect on the fetus, if there are no adequate and well-controlled studies in humans, and if the benefits from the use of the drug in pregnant women may be acceptable despite its potential risks
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but the potential benefits from the use of the drug in pregnant women may be acceptable despite its potential risks
X Studies in animals or humans have demonstrated fetal abnormalities or if there is positive evidence of fetal risk based on adverse reaction reports from investigational or marketing experience, or both, and the risk of the use of the drug in a pregnant woman clearly outweighs any possible benefit

Risk Categories of Antimicrobial Agents for TdP or QTc Interval Prolongation

Risk categories for antimicrobial agents known to have an association with TdP Return to Top

  • Drugs with known TdP risk
  • Drugs with possible TdP risk
  • Drugs with conditional TdP risk
  • Drugs to be avoided by congenital Long QT

Torsades de pointes risk stratification schedules for antimicrobial agents Return to Top

  • Schedule I (Highest TdP risk, potent IKr blockers, TdP risk >1%)
  • Not available
  • Schedule II (Significant risk for TdP, particularly when coadministered with CYP inhibitors, relatively potent IKr blockade)
  • Not available
  • Schedule III (Risk for TdP is described, IKr blockade, particularly when coadministered with CYP inhibitors)
  • Schedule IV (Minimal risk for TdP, case reports of TdP, mild IKr blockade, may have CYP interactions)
  • Schedule V (Questionable or minimal risk for QT interval prolongation or TdP)

CYP450 Isozymes Drug Interactions

Substrates of Cytochrome P-450 Isozymes

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Inhibitors of Cytochrome P-450 Isozymes

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Inducers of Cytochrome P-450 Isozymes

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Dosage Adjustment in Renal or Hepatic Impairment

Dosage adjustment in renal impairment Return to Top

Renal dose of antimicrobial agents (consult FDA package insert for details):


Dosage adjustment in hepatic impairment Return to Top

Hepatic dose of antimicrobial agents (consult FDA package insert for details):

Antimicrobial Agent Drug Category Dosing Recommendation
Abacavir Antiviral agent
  • A dose of 200 mg abacavir administered twice daily is recommended for patients with mild liver disease.
  • The safety, efficacy, and pharmacokinetics of abacavir have not been studied in patients with moderate or severe hepatic impairment; therefore, abacavir is contraindicated in these patients.
Atazanavir Antiviral agent
  • Mild hepatic impairment (Child-Pugh class A): 400 mg once daily
  • Moderate hepatic impairment (Child-Pugh class B): 300 mg once daily
  • Severe hepatic impairment (Child-Pugh class C): not recommended
Caspofungin Antifungal agent
  • Mild hepatic impairment (Child-Pugh score 5–6): no dosage adjustment is required
  • Moderate hepatic impairment (Child-Pugh score 7–9): 35 mg once daily following a 70-mg loading dose on day 1
  • Severe hepatic impairment (Child-Pugh score 10–15): no clinical experience available
  • Pediatric patients with any degree of hepatic impairment: dosing recommendations are not available
Chloramphenicol Antibacterial agent
  • Adults with impairment of hepatic function may have reduced ability to metabolize and excrete the drug. In instances of impaired metabolic processes, dosages should be adjusted accordingly. Precise control of concentration of the drug in the blood should be carefully followed in patients with impaired metabolic processes by the available microtechniques.
Clindamycin Antibacterial agent
  • This product contains benzyl alcohol as a preservative and has been associated with gasping syndrome in pediatric patients. The risk of benzyl alcohol toxicity depends on the quantity administered and the hepatic capacity to detoxify the chemical.
Darunavir-Ritonavir Antiviral agent
  • No dose adjustment of Darunavir/ritonavir is necessary for patients with either mild or moderate hepatic impairment.
  • No pharmacokinetic or safety data are available regarding the use of Darunavir/ritonavir in subjects with severe hepatic impairment; therefore, Darunavir/ritonavir is not recommended for use in patients with severe hepatic impairment.
Delavirdine Antiretroviral agent
  • Delavirdine is metabolized primarily by the liver. Caution should be exercised when administering delavirdine to patients with impaired hepatic function.
Efavirenz Antiretroviral agent
  • Patients with mild hepatic impairment may be treated with efavirenz without any adjustment in dose. Because of the extensive cytochrome P450-mediated metabolism of efavirenz and limited clinical experience in patients with hepatic impairment, caution should be exercised in administering efavirenz to these patients.
  • Efavirenz is not recommended for patients with moderate or severe hepatic impairment because there are insufficient data to determine whether dose adjustment is necessary.
Fosamprenavir Antiretroviral agent
  • Mild Hepatic Impairment (Child-Pugh score 5–6): 700 mg twice daily without ritonavir (therapy-naive) or 700 mg twice daily plus ritonavir 100 mg once daily (therapy-naive or protease inhibitor-experienced)
  • Moderate Hepatic Impairment (Child-Pugh score 7–9): 700 mg twice daily without ritonavir (therapy-naive), or 450 mg twice daily plus ritonavir 100 mg once daily (therapy-naive or protease inhibitor-experienced)
  • Severe Hepatic Impairment (Child-Pugh score 10–15): 350 mg twice daily without ritonavir (therapy-naive) or 300 mg twice daily plus ritonavir 100 mg once daily (therapy-naive or protease inhibitor-experienced)
  • Pediatric patients with any degree of hepatic impairment: dosing recommendations are not available
Indinavir Antiretroviral agent
  • Patients with mild to moderate hepatic insufficiency and clinical evidence of cirrhosis had evidence of decreased metabolism of indinavir.
  • Indinavir pharmacokinetics have not been studied in patients with severe hepatic insufficiency.
Isoniazid Antimycobacterial agent
  • Patients with hepatitis attributed to isoniazid should be given appropriate treatment with alternative drugs. If isoniazid must be reinstituted, it should be administered only after symptoms and laboratory abnormalities have cleared. The drug should be restarted in very small and gradually increasing doses and should be withdrawn immediately if there is any indication of recurrent liver involvement.
  • Preventive treatment with isoniazid should be deferred in patients with acute hepatic disease.
Itraconazole Antifungal agent
  • Limited data are available on the use of itraconazole in patients with hepatic impairment. Caution should be exercised when this drug is administered in this patient population.
Lopinavir-Ritonavir Antiretroviral agent
  • Lopinavir is principally metabolized and eliminated by the liver. Caution should be exercised when administering Lopinavir-Ritonavir to subjects with hepatic impairment.
  • Lopinavir-Ritonavir has not been studied in patients with severe hepatic impairment.
Metronidazole Antibacterial agent
  • Patients with hepatic impairment metabolize metronidazole slowly, with resultant accumulation of metronidazole in the plasma.
  • For patients with mild to moderate hepatic impairment, no dosage adjustment is needed but these patients should be monitored for metronidazole associated adverse events.
  • For patients with severe hepatic impairment (Child-Pugh class C), a reduction in metronidazole dosage by 50% is recommended.
Nafcillin Antibacterial agent
  • For patients with hepatic insufficiency, measurement of nafcillin serum levels should be performed and dosage adjusted accordingly.
Nelfinavir Antiretroviral agent
  • Nelfinavir may be used in patients with mild hepatic impairment without any dose adjustment.
  • Nelfinavir should not be used in patients with either moderate or severe hepatic impairment.
Nevirapine Antiretroviral agent
  • Nevirapine Nis contraindicated in patients with moderate (Child-Pugh class B) or severe (Child-Pugh class C) hepatic impairment.
Quinupristin-Dalfopristin Antibacterial agent
  • The effect of dose reduction or increase in dosing interval on the pharmacokinetics of Quinupristin-Dalfopristin in patients with hepatic impairment has not been studied. No recommendations can be made regarding the appropriate dose modification.
Rifabutin Antimycobacterial agent
  • Mild hepatic impairment does not require a dose modification.
Rimantadine Antiviral agent
  • In patients with severe hepatic dysfunction, a dose reduction to 100 mg daily is recommended.
Ritonavir Antiretroviral agent
  • No dose adjustment of ritonavir is necessary for patients with either mild (Child-Pugh class A) or moderate (Child-Pugh class B) hepatic impairment.
  • No pharmacokinetic or safety data are available regarding the use of ritonavir in subjects with severe hepatic impairment (Child-Pugh class C); therefore, ritonavir is not recommended for use in patients with severe hepatic impairment.
Telithromycin Antibacterial agent
  • Telithromycin may be administered without dosage adjustment in the presence of hepatic impairment.
  • In the presence of severe renal impairment (CLCR < 30 mL/min) with coexisting hepatic impairment, the dose should be reduced to 400 mg once daily.
Tigecycline Antibacterial agent
  • No dosage adjustment is warranted in patients with mild to moderate hepatic impairment (Child-Pugh class A and Child-Pugh class B).
  • In patients with severe hepatic impairment (Child-Pugh class C), the initial dose should be 100 mg followed by a reduced maintenance dose of 25 mg every 12 hours.
Tinidazole Antifungal agent
  • There are no data on tinidazole pharmacokinetics in patients with impaired hepatic function. Usual recommended doses of tinidazole should be administered cautiously in patients with hepatic dysfunction.
Voriconazole Antifungal agent
  • Tablet: Voriconazole tablets have not been studied in patients with severe hepatic cirrhosis or in patients with chronic hepatitis B or chronic hepatitis C disease. Voriconazole tablets should only be used in patients with severe hepatic impairment if the benefit outweighs the potential risk. Patients with hepatic insufficiency must be carefully monitored for drug toxicity.
  • Solution: The maintenance dose should be reduced in patients with mild to moderate hepatic impairment. There are no pharmacokinetic data to allow for dosage adjustment recommendations in patients with severe hepatic impairment.