Interferon alfa-2b contraindications

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Interferon alfa-2b
INTRON A® FDA Package Insert
Description
Clinical Pharmacology
Indications and Usage
Contraindications
Warnings and Precautions
Adverse Reactions
Drug Interactions
Overdosage
Dosage and Administration
How Supplied
Labels and Packages

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sheng Shi, M.D. [2]

Contraindications

INTRON® A is contraindicated in patients with:

  • Hypersensitivity to interferon alpha or any component of the product
  • Autoimmune hepatitis
  • Decompensated liver disease

INTRON A and REBETOL® combination therapy is additionally contraindicated in:

  • Patients with hypersensitivity to ribavirin or any other component of the product
  • Women who are pregnant
  • Men whose female partners are pregnant
  • Patients with hemoglobinopathies (e.g., thalassemia major, sickle cell anemia)
  • Patients with creatinine clearance less than 50 mL/min.

See REBETOL prescribing information for additional information.[1]

References

  1. "INFERGEN (INTERFERON ALFACON-1) INJECTION [KADMON PHARMACEUTICALS, LLC]". Retrieved 8 January 2014.

Adapted from the FDA Package Insert.