Isograft
WikiDoc Resources for Isograft |
Articles |
---|
Most recent articles on Isograft |
Media |
Evidence Based Medicine |
Clinical Trials |
Ongoing Trials on Isograft at Clinical Trials.gov Clinical Trials on Isograft at Google
|
Guidelines / Policies / Govt |
US National Guidelines Clearinghouse on Isograft
|
Books |
News |
Commentary |
Definitions |
Patient Resources / Community |
Directions to Hospitals Treating Isograft Risk calculators and risk factors for Isograft
|
Healthcare Provider Resources |
Causes & Risk Factors for Isograft |
Continuing Medical Education (CME) |
International |
|
Business |
Experimental / Informatics |
Overview
An Isograft is a graft of tissue between two individuals who are genetically identical (i.e. monozygotic twins). Transplant rejection between two such individuals virtually never occurs.
As monozygotic twins have the same major histocompatibility complex, there is very rarely any rejection of transplanted tissue by the adaptive immune system. Furthermore, there is virtually no incidence of graft-versus-host disease. This forms the basis for why the proffered choice of a physician considering an organ donor will be a monozygotic twin.