Isoxsuprine Oral (patient information)

Why this medication is prescribed

Isoxsuprine is used to relieve the symptoms of central and peripheral vascular diseases such as arteriosclerosis, Buerger's disease, and Raynaud's disease.

This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.

How this medication should be used

Isoxsuprine comes as a tablet to take by mouth. It is usually taken three or four times a day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take isoxsuprine exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Other uses for this medicine

Isoxsuprine is also used occasionally to treat menstrual pain or prevent premature labor. Talk to your doctor about the possible risks of using this drug for your condition.

Special precautions

Before taking isoxsuprine:

• tell your doctor and pharmacist if you are allergic to isoxsuprine or any other drugs.
• tell your doctor and pharmacist what prescription and nonprescription medications and vitamins you are taking.
• tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking isoxsuprine, call your doctor immediately.
• if you are having surgery, including dental surgery, tell your doctor or dentist that you are taking isoxsuprine.
• you should know that this drug may make you drowsy or dizzy. Do not drive a car or operate machinery until you know how isoxuprine will affect you. Avoid sudden changes in posture and get up slowly when lying down.

What to do if you forget a dose

Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

Side effects

Minor side effects

Isoxsuprine may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

• weakness
• dizziness
• flushing (feeling of warmth)
• upset stomach
• vomiting
• stomach pain

Severe side effects

If you experience any of the following symptoms, call your doctor immediately:

• rash
• fast heartbeat
• chest pain

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at http://www.fda.gov/MedWatch/report.htm] or by phone [1-800-332-1088].

Storage conditions needed for this medication

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.

In case of emergency/overdose

In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.

Other information

Keep all appointments with your doctor and the laboratory.

Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.

Brand names

• Vasodilan®
• Voxuprine®