LY6G6E

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Identifiers
Aliases
External IDs	GeneCards: [1]
Orthologs
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a
Wikidata
View/Edit Human

Lymphocyte antigen 6 complex, locus G6E (pseudogene) is a protein that in humans is encoded by the LY6G6E gene.

Function

LY6G6E belongs to a cluster of leukocyte antigen-6 (LY6) genes located in the major histocompatibility complex (MHC) class III region on chromosome 6. Members of the LY6 superfamily typically contain 70 to 80 amino acids, including 8 to 10 cysteines. Most LY6 proteins are attached to the cell surface by a glycosylphosphatidylinositol (GPI) anchor that is directly involved in signal transduction.

Further reading

• Mallya M, Campbell RD, Aguado B (October 2006). "Characterization of the five novel Ly-6 superfamily members encoded in the MHC, and detection of cells expressing their potential ligands". Protein Science. 15 (10): 2244–56. doi:10.1110/ps.062242606. PMC 2242401. PMID 17008713.
• Ribas G, Neville M, Wixon JL, Cheng J, Campbell RD (July 1999). "Genes encoding three new members of the leukocyte antigen 6 superfamily and a novel member of Ig superfamily, together with genes encoding the regulatory nuclear chloride ion channel protein (hRNCC) and an N omega-N omega-dimethylarginine dimethylaminohydrolase homologue, are found in a 30-kb segment of the MHC class III region". Journal of Immunology. 163 (1): 278–87. PMID 10384126.
• Vignal C, Bansal AT, Balding DJ, Binks MH, Dickson MC, Montgomery DS, Wilson AG (January 2009). "Genetic association of the major histocompatibility complex with rheumatoid arthritis implicates two non-DRB1 loci". Arthritis and Rheumatism. 60 (1): 53–62. doi:10.1002/art.24138. PMID 19116923.
• "Complete sequence and gene map of a human major histocompatibility complex. The MHC sequencing consortium". Nature. 401 (6756): 921–3. October 1999. doi:10.1038/44853. PMID 10553908.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.