Labetalol Oral (patient information)

IMPORTANT WARNING

Do not stop taking labetalol without talking to your doctor first. If labetalol is stopped suddenly, it may cause chest pain or heart attack in some people.

Why this medication is prescribed

Labetalol is used to treat high blood pressure. It relaxes your blood vessels so your heart doesn't have to pump as hard. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.

How this medication should be used

Labetalol comes as a tablet to take by mouth. It usually is taken two or three times a day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take labetalol exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Labetalol controls high blood pressure but does not cure it. Continue to take labetalol even if you feel well. Do not stop taking labetalol without talking to your doctor.

Other uses for this medicine

Labetalol is also used sometimes to treat chest pain (angina) and to treat patients with tetanus. Talk to your doctor about the possible risks of using this drug for your condition.

Special precautions

Before taking labetalol:

• tell your doctor and pharmacist if you are allergic to labetalol or any other drugs.
• tell your doctor and pharmacist what prescription and nonprescription medications you are taking, especially other medications for high blood pressure or heart disease; cimetidine (Tagamet); nitroglycerin; medications for asthma, headaches, allergies, colds, or pain; and vitamins.
• tell your doctor if you have or have ever had heart, kidney, or liver disease; asthma or other lung disease; severe allergies; diabetes; or pheochromocytoma.
• tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking labetalol, call your doctor.
• if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking labetalol.
• you should know that this drug may make you drowsy. Do not drive a car or operate machinery until you know how this drug affects you.
• remember that alcohol can add to the drowsiness caused by this drug.

Special dietary instructions

Talk to your doctor before using salt substitutes containing potassium. If your doctor prescribes a low-salt or low-sodium diet, follow these directions carefully.

Labetalol may be taken with or without food, but it should be taken the same way every day.

What to do if you forget a dose

Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

Side Effects

Minor Side Effects

Labetalol may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

• dizziness
• tingling scalp or skin
• lightheadedness
• excessive tiredness
• headache
• upset stomach
• stuffy nose

Severe Side Effects

If you experience any of the following symptoms, call your doctor immediately:

• shortness of breath or wheezing
• swelling of the feet and lower legs
• sudden weight gain
• chest pain

If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online [at http://www.fda.gov/MedWatch/report.htm] or by phone [1-800-332-1088].

Storage conditions needed for this medication

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.

In case of emergency/overdose

In case of overdose, call your local poison control center at 1-800-222-1222. If the victim has collapsed or is not breathing, call local emergency services at 911.

Other information

Keep all appointments with your doctor and the laboratory. Your blood pressure should be checked regularly to determine your response to labetalol. Your doctor may ask you to check your pulse (heart rate). Ask your pharmacist or doctor to teach you how to take your pulse. If your pulse is faster or slower than it should be, call your doctor.

Do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.

Brand names

• Normodyne®
• Trandate®