Lactic acidosis risk factors
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Saud Khan M.D.
Overview
Common risk factors in the development of lactic acidosis are:
- Diabetics taking metformin and SGLT2 inhibitors, especially in conjunction with active COVID-19[1]
- Underlying sepsis
- Septic, cardiogenic or haemorrhagic shock
Risk factors
Lactic acidosis predisposing factors are reported to include:
- Acute kidney injury
- Previous history of lactic acidosis
- Hypovolemia
- Hemodynamic instability due to infection or other causes
- Seizure
- Concurrent liver disease
- Alcohol abuse
- Acute heart failure/Myocardial infarction
- Shock due to any cause
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References
- ↑ Orioli L, Hermans MP, Thissen JP, Maiter D, Vandeleene B, Yombi JC (2020). "COVID-19 in diabetic patients: Related risks and specifics of management". Ann Endocrinol (Paris). 81 (2–3): 101–109. doi:10.1016/j.ando.2020.05.001. PMC 7217100 Check
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