Large cell carcinoma of the lung CT
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Maria Fernanda Villarreal, M.D. [2]
Overview
Computed tomography is the method of choice for the diagnosis of non-small cell lung cancer. On CT, characteristic findings of large cell carcinoma of the lung, include: ground-glass opacity, rounded mass, large mediastinal node involvement, nodular pleural thickening, and lobar collapse.[1][2]
CT
- Computed tomography is the method of choice for the diagnosis of non-small cell lung cancers
- In some cases, non-small cell lung cancers require further evaluation with MRI
- Common features of CT scan for the diagnosis of non-small cell lung cancers, include:[3]
- Assessment of the main bronchi
- Evaluation of the entire thorax
- Detection of chest wall invasion
- Assessment of hiliar and mediastinal invasion/adenopathy
- Determination of non-small cell lung cancer staging
- Precise determination of size and tumor dimensions
- Detection of liver, bone, adrenal , and brain metastasis
- On CT, common findings of large cell carcinoma of the lung, include:[3]
- Ground glass opacity
- Rounded and well-circumscribed mass
- Large mediastinal nodules/masses
- Rapid growth
- Lymph node involvement
- Frequently subcarinal
- Nodular pleural thickening
- Pleural effusion
- May be loculated
- Usually large
- Narrowing of the lobar and segmental bronchi on the right, due to filling defect.
- Atelectasis
- Early metastasis to brain
References
- ↑ Rosado-de-Christenson ML, Templeton PA, Moran CA (1994). "Bronchogenic carcinoma: radiologic-pathologic correlation". Radiographics. 14 (2): 429–46, quiz 447–8. doi:10.1148/radiographics.14.2.8190965. PMID 8190965.
- ↑ Parker MS, Chasen MH, Paul N (2009). "Radiologic signs in thoracic imaging: case-based review and self-assessment module". AJR Am J Roentgenol. 192 (3 Suppl): S34–48. doi:10.2214/AJR.07.7081. PMID 19234288.
- ↑ 3.0 3.1 Kundel HL (1981). "Predictive value and threshold detectability of lung tumors". Radiology. 139 (1): 25–9. doi:10.1148/radiology.139.1.7208937. PMID 7208937.