Leiomyosarcoma classfication

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Nima Nasiri, M.D.[2]

Overview

There is two types of classification for uterine sarcomas, the FIGO (International Federation of Gynecology and Obstetrics) system and the American Joint Committee on Cancer TNM staging system both classifies uterine sarcoma based on T(tumor size), N(spread to nearby lymph nodes) and M(distant metastasis).

Classification

The FIGO (International Federation of Gynecology and Obstetrics) system and the American Joint Committee on Cancer TNM staging system both classifies uterine sarcoma based on T(tumor size), N(spread to nearby lymph nodes) and M(distant metastasis) staging, the table below summarizes the staging of leiomyosarcoma.

Stage	Stage grouping	FIGO stage	Stage description
I	T1 N0 M0	I	The cancer is growing in the uterus but has not started growing outside the uterus. It has not spread to nearby lymph nodes (N0) or to distant sites (M0).
IA	T1a N0 M0	IA	The cancer is only in the uterus and is no larger than 5 cm across (about 2 inches) (T1a). It has not spread to nearby lymph nodes (N0) or to distant sites (M0).
IB	T1a N0 M0	IB	The cancer is only in the uterus and is larger than 5 cm across (about 2 inches). (T1b). It has not spread to nearby lymph nodes (N0) or to distant sites (M0).
II	T1a N0 M0	II	The cancer is growing outside the uterus but is not growing outside of the pelvis (T2). It has not spread to nearby lymph nodes (N0) or to distant sites (M0).
IIIA	T3a N0 M0	IIIA	The cancer is growing into tissues of the abdomen in one place only (T3a). It has not spread to nearby lymph nodes (N0) or to distant sites (M0).
IIIB	T3a N0 M0	IIIB	The cancer is growing into tissues of the abdomen in 2 or more places (T3b). It has not spread to nearby lymph nodes (N0) or to distant sites (M0).
IIIC	T1-T3 N1 M0	IIIC	The cancer is growing in the body of the uterus and it might have spread into tissues of the abdomen, but is not growing into the bladder or rectum (T1 to T3). The cancer has spread to nearby lymph nodes (N1), but not to distant sites (M0).
IVA	T4 Any N M0	IVA	Cancer has spread to the rectum or urinary bladder (T4). It might or might not have spread to nearby lymph nodes (Any N) but has not spread to distant sites (M0).
IVB	Any T Any N M1	IVB	The cancer has spread to distant sites such as the lungs, bones, or liver (tumor in the uterus can be any size and may or may not have grown into tissues in the pelvis and/or abdomen (including the bladder or rectum) (any T) and it might or might not have spread to nearby lymph nodes (Any N).