Linear IgA bullous dermatosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Kiran Singh, M.D. [2]

Synonyms and keywords:

Overview

Linear IgA bullous dermatosis (also known as "Linear IgA dermatosis") is frequently associated with medication exposure, especially vancomycin, with men and women being equally affected. It was first described by Tadeusz Chorzelski in 1979. Linear IgA dermatosis is a rare immune-mediated blistering skin disease that may be divided into two types:

• Adult linear IgA disease is an acquired, autoimmune blistering disease that may present with a clinical pattern of vesicles indistinguishable from dermatitis herpetiformis, or with vesicles and bullae in a bullous pemphigoid-like appearance.
• Childhood linear IgA disease (also known as "Chronic bullous disease of childhood") is an acquired, self-limited bullous disease that may begin by the time the patient is age 2 to 3 and usually remits by age 13.

Diagnosis

Physical Examination

Skin

Trunk And Extremities

• 
  Childhood linear IgA disease. Adapted from Dermatology Atlas.
• 
  Childhood linear IgA disease. Adapted from Dermatology Atlas.
• 
  Childhood linear IgA disease. Adapted from Dermatology Atlas.
• 
  Childhood linear IgA disease. Adapted from Dermatology Atlas.
• 
  Childhood linear IgA disease. Adapted from Dermatology Atlas.
• 
  Childhood linear IgA disease. Adapted from Dermatology Atlas.
• 
  Childhood linear IgA disease. Adapted from Dermatology Atlas.
• 
  Childhood linear IgA disease. Adapted from Dermatology Atlas.
• 
  Childhood linear IgA disease. Adapted from Dermatology Atlas.
• 
  Childhood linear IgA disease. Adapted from Dermatology Atlas.
• 
  Childhood linear IgA disease. Adapted from Dermatology Atlas.
• 
  Childhood linear IgA disease. Adapted from Dermatology Atlas.
• 
  Childhood linear IgA disease. Adapted from Dermatology Atlas.
• 
  Childhood linear IgA disease. Adapted from Dermatology Atlas.
• 
  Childhood linear IgA disease. Adapted from Dermatology Atlas.
• 
  Childhood linear IgA disease. Adapted from Dermatology Atlas.
• 
  Childhood linear IgA disease. Adapted from Dermatology Atlas.
• 
  Childhood linear IgA disease. Adapted from Dermatology Atlas.
• 
  Childhood linear IgA disease. Adapted from Dermatology Atlas.
• 
  Childhood linear IgA disease. Adapted from Dermatology Atlas.
• 
  Childhood linear IgA disease. Adapted from Dermatology Atlas.

See also

• Skin lesion
• List of cutaneous conditions
• List of target antigens in pemphigoid
• List of immunofluorescence findings for autoimmune bullous conditions