List of human genes
Jump to navigation
Jump to search
This list describes some of the most notable genes present in the human genome.
Note: this does not attempt to be an exhausive list of genes, of which there are tens of thousands for humans alone: this is intended to be a list of genes which are particularly notable in scientific research or in their role in relation to disease, or have featured in a recent significant research paper or news story.
Genes notable for their function
| HUGO Symbol | Locus | Gene product | Associated disease | Notes | Genecard |
| ALB | 4q11-q13 | Serum albumin | -- | The most abundant protein in human blood plasma | Template:Genecard |
| BCL2 | 18q21.3 | Apoptosis regulator Bcl-2 / B-cell CLL/lymphoma 2 | Several cancers | The prototype anti-apoptotic protein | Template:Genecard |
| CCR5 | 3p21 | chemokine (C-C motif) receptor 5 | -- | Has an important role in resistance to infection. | Template:Genecard |
| CD4 | 12pter-p12 | CD4 antigen | -- | The prototype marker for T helper cells | Template:Genecard |
| CD8 | 2p12 | CD8 antigen | -- | The prototype marker for cytotoxic T cells | Template:Genecard |
| IL2 | 4q26-q27 | Interleukin 2 | Various cancers | Strong pro-inflammatory cytokine | Template:Genecard |
| IL10 | 1q31-q32 | Interleukin 10 | -- | anti-inflammatory cytokine | Template:Genecard |
Genes that have attracted media attention
| HUGO Symbol | Locus | Gene product | Associated disease | Notes | Genecard |
| BRCA1 | 17q21 | Breast cancer 1, early onset | Breast cancer | Myriad Genetics owns a controversial patent on this gene [1] | Template:Genecard |
| BRCA2 | 13q12-13 | Breast cancer 2, early onset | Breast cancer | Myriad Genetics owns a controversial patent on this gene [2] | Template:Genecard |
| CD28 | 2q33 | CD28 antigen | -- | The target of the drug TGN1412, which had a dramatic outcome of its first clinical trial in 2006. | Template:Genecard |
| ZBTB7A | 19p13.3 | Zbtb7 / POK erythroid myeloid ontogenic factor | Cancer | Originally called POKemon, the gene was renamed after legal threats from Pokémon USA [3]. | Template:Genecard |