Lung cancer history and symptoms
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Kim-Son H. Nguyen M.D. Cafer Zorkun, M.D., Ph.D. [2] Shanshan Cen, M.D. [3]
Overview
Common symptoms of lung cancer include difficulty breathing, hemoptysis, chronic coughing, chest pain, weakness and wasting, difficulty speaking, and symptoms related to paraneoplastic syndromes.
History and Symptoms
History
- Specific areas of focus when obtaining the history are outlined below:[1]
- Age
- Family history of cancer
- Personal history of cancer
- Positive history of active/passive smoking
- Number of cigarettes/year
- Number of years/months of active smoking
- Number of years/months of second-hand smoking
- Number of years/months since smoking cessation
- Previous primary infection of tuberculosis
- Onset of pulmonary symptoms
- Previous or current lung disease, such as:
- Several patient factors may influence the likelihood of a benign versus a malignant condition; these include previous exposure to smoke or other carcinogens such as asbestos, and previously diagnosed cancer or respiratory infections.
- A patient with airway symptoms, especially hemoptysis, is more likely to have cancer compared to a patient with no respiratory symptoms.
Common Symptoms
Symptoms of Paraneoplastic Syndromes
- Various paraneoplastic phenomena can arise in the setting of lung cancer:[4][5]
Endocrine
Neurological
Other
References
- ↑ Kaerlev L, Teglbjaerg PS, Sabroe S, Kolstad HA, Ahrens W, Eriksson M, Guénel P, Gorini G, Hardell L, Cyr D, Zambon P, Stang A, Olsen J (2002). "The importance of smoking and medical history for development of small bowel carcinoid tumor: a European population-based case-control study". Cancer Causes Control. 13 (1): 27–34. PMID 11899115.
- ↑ Hamilton, W (Dec 2005). "What are the clinical features of lung cancer before the diagnosis is made? A population based case-control study". Thorax. BMJ Publishing Group Ltd. 60 (12): 1059–1065. PMID 16227326. Unknown parameter
|coauthors=ignored (help) - ↑ Buccheri, G. (2004). "Lung cancer: clinical presentation and specialist referral time". European Respiratory Journal. 24 (6): 898–904. doi:10.1183/09031936.04.00113603. ISSN 0903-1936.
- ↑ Honnorat, J (May 2007). "Paraneoplastic neurological syndromes". Orphanet Journal of Rare Diseases. BioMed Central Ltd. 2: 22. doi:10.1186/1750-1172-2-22. PMID 17480225. Retrieved 2007-09-05. Unknown parameter
|coauthors=ignored (help) - ↑ Kubo M, Ihn H, Yamane K, Kikuchi K, Yazawa N, Soma Y; et al. (2000). "Serum KL-6 in adult patients with polymyositis and dermatomyositis". Rheumatology (Oxford). 39 (6): 632–6. PMID 10888708.