In molecular biology, Maternally expressed 8 (non-protein coding), also known as MEG8 or Rian (RNA Imprinted and Accumulated in Nucleus), is a long non-coding RNA. It is an imprinted gene, which is maternally expressed. It is expressed in the nucleus and (in an eight-week-old sheep) is preferentially expressed in skeletal muscle.[1][2]
↑Hatada I, Morita S, Obata Y, Sotomaru Y, Shimoda M, Kono T (2001). "Identification of a new imprinted gene, Rian, on mouse chromosome 12 by fluorescent differential display screening". J Biochem. 130 (2): 187–90. doi:10.1093/oxfordjournals.jbchem.a002971. PMID11481034.