MPG (gene)

N-methylpurine-DNA glycosylase
File:PBB Protein MPG image.jpg PDB rendering based on 1bnk.
Available structures PDB Ortholog search: Template:Homologene2PDBe PDBe, Template:Homologene2uniprot RCSB List of PDB id codes 1bnk​, 1ewn​, 1f4r​, 1f6o​
Identifiers
Symbols	MPG ; AAG; APNG; CRA36.1; MDG; Mid1; PIG11; PIG16; anpg
External IDs	Template:OMIM5 Template:MGI HomoloGene: 1824
Gene ontology Molecular function Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Template:GNF GO Biological process Template:GNF GO Template:GNF GO
RNA expression pattern
File:PBB GE MPG 203686 at tn.png
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

N-methylpurine-DNA glycosylase, also known as MPG, is a human gene.

Further reading

• Hollis T, Lau A, Ellenberger T (2000). "Structural studies of human alkyladenine glycosylase and E. coli 3-methyladenine glycosylase". Mutat. Res. 460 (3–4): 201–10. PMID 10946229.CS1 maint: Multiple names: authors list (link)
• O'Connor TR, Laval J (1991). "Human cDNA expressing a functional DNA glycosylase excising 3-methyladenine and 7-methylguanine". Biochem. Biophys. Res. Commun. 176 (3): 1170–7. PMID 1645538.
• Chakravarti D, Ibeanu GC, Tano K, Mitra S (1991). "Cloning and expression in Escherichia coli of a human cDNA encoding the DNA repair protein N-methylpurine-DNA glycosylase". J. Biol. Chem. 266 (24): 15710–5. PMID 1874728.CS1 maint: Multiple names: authors list (link)
• Samson L, Derfler B, Boosalis M, Call K (1991). "Cloning and characterization of a 3-methyladenine DNA glycosylase cDNA from human cells whose gene maps to chromosome 16". Proc. Natl. Acad. Sci. U.S.A. 88 (20): 9127–31. PMID 1924375.CS1 maint: Multiple names: authors list (link)
• Kielman MF, Smits R, Devi TS; et al. (1993). "Homology of a 130-kb region enclosing the alpha-globin gene cluster, the alpha-locus controlling region, and two non-globin genes in human and mouse". Mamm. Genome. 4 (6): 314–23. PMID 8318735.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Vickers MA, Vyas P, Harris PC; et al. (1993). "Structure of the human 3-methyladenine DNA glycosylase gene and localization close to the 16p telomere". Proc. Natl. Acad. Sci. U.S.A. 90 (8): 3437–41. PMID 8475094.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Lau AY, Schärer OD, Samson L; et al. (1998). "Crystal structure of a human alkylbase-DNA repair enzyme complexed to DNA: mechanisms for nucleotide flipping and base excision". Cell. 95 (2): 249–58. PMID 9790531.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Miao F, Bouziane M, Dammann R; et al. (2000). "3-Methyladenine-DNA glycosylase (MPG protein) interacts with human RAD23 proteins". J. Biol. Chem. 275 (37): 28433–8. doi:10.1074/jbc.M001064200. PMID 10854423.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Lau AY, Wyatt MD, Glassner BJ; et al. (2001). "Molecular basis for discriminating between normal and damaged bases by the human alkyladenine glycosylase, AAG". Proc. Natl. Acad. Sci. U.S.A. 97 (25): 13573–8. doi:10.1073/pnas.97.25.13573. PMID 11106395.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Daniels RJ, Peden JF, Lloyd C; et al. (2001). "Sequence, structure and pathology of the fully annotated terminal 2 Mb of the short arm of human chromosome 16". Hum. Mol. Genet. 10 (4): 339–52. PMID 11157797.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Kim NK, An HJ, Kim HJ; et al. (2002). "Altered expression of the DNA repair protein, N-methylpurine-DNA glycosylase (MPG) in human gonads". Anticancer Res. 22 (2A): 793–8. PMID 12014652.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Vallur AC, Feller JA, Abner CW; et al. (2002). "Effects of hydrogen bonding within a damaged base pair on the activity of wild type and DNA-intercalating mutants of human alkyladenine DNA glycosylase". J. Biol. Chem. 277 (35): 31673–8. doi:10.1074/jbc.M204475200. PMID 12077143.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Kim NK, Ahn JY, Song J; et al. (2003). "Expression of the DNA repair enzyme, N-methylpurine-DNA glycosylase (MPG) in astrocytic tumors". Anticancer Res. 23 (2B): 1417–23. PMID 12820404.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Watanabe S, Ichimura T, Fujita N; et al. (2004). "Methylated DNA-binding domain 1 and methylpurine-DNA glycosylase link transcriptional repression and DNA repair in chromatin". Proc. Natl. Acad. Sci. U.S.A. 100 (22): 12859–64. doi:10.1073/pnas.2131819100. PMID 14555760.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• O'Brien PJ, Ellenberger T (2003). "Human alkyladenine DNA glycosylase uses acid-base catalysis for selective excision of damaged purines". Biochemistry. 42 (42): 12418–29. doi:10.1021/bi035177v. PMID 14567703.
• O'Brien PJ, Ellenberger T (2004). "Dissecting the broad substrate specificity of human 3-methyladenine-DNA glycosylase". J. Biol. Chem. 279 (11): 9750–7. doi:10.1074/jbc.M312232200. PMID 14688248.
• Likhite VS, Cass EI, Anderson SD; et al. (2004). "Interaction of estrogen receptor alpha with 3-methyladenine DNA glycosylase modulates transcription and DNA repair". J. Biol. Chem. 279 (16): 16875–82. doi:10.1074/jbc.M313155200. PMID 14761960.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Hitchcock TM, Dong L, Connor EE; et al. (2004). "Oxanine DNA glycosylase activity from Mammalian alkyladenine glycosylase". J. Biol. Chem. 279 (37): 38177–83. doi:10.1074/jbc.M405882200. PMID 15247209.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)