MT3

Metallothionein 3
File:PBB Protein MT3 image.jpg PDB rendering based on 2f5h.
Available structures PDB Ortholog search: Template:Homologene2PDBe PDBe, Template:Homologene2uniprot RCSB List of PDB id codes 2f5h​, 2fj4​, 2fj5​
Identifiers
Symbols	MT3 ; GIF; GIFB; GRIF
External IDs	Template:OMIM5 Template:MGI HomoloGene: 4346
Gene ontology Molecular function Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Biological process Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO Template:GNF GO
RNA expression pattern
File:PBB GE MT3 205970 at tn.png
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Metallothionein 3, also known as MT3, is a human gene.

Further reading

• Aschner M (1996). "The functional significance of brain metallothioneins". FASEB J. 10 (10): 1129–36. PMID 8751715.
• Tsuji S, Kobayashi H, Uchida Y; et al. (1993). "Molecular cloning of human growth inhibitory factor cDNA and its down-regulation in Alzheimer's disease". EMBO J. 11 (13): 4843–50. PMID 1464312.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Palmiter RD, Findley SD, Whitmore TE, Durnam DM (1992). "MT-III, a brain-specific member of the metallothionein gene family". Proc. Natl. Acad. Sci. U.S.A. 89 (14): 6333–7. PMID 1631128.CS1 maint: Multiple names: authors list (link)
• Uchida Y, Takio K, Titani K; et al. (1991). "The growth inhibitory factor that is deficient in the Alzheimer's disease brain is a 68 amino acid metallothionein-like protein". Neuron. 7 (2): 337–47. PMID 1873033.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Hewitt JE, Gordon MM, Taggart RT; et al. (1991). "Human gastric intrinsic factor: characterization of cDNA and genomic clones and localization to human chromosome 11". Genomics. 10 (2): 432–40. PMID 2071148.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Amoureux MC, Wurch T, Pauwels PJ (1995). "Modulation of metallothionein-III mRNA content and growth rate of rat C6-glial cells by transfection with human 5-HT1D receptor genes". Biochem. Biophys. Res. Commun. 214 (2): 639–45. doi:10.1006/bbrc.1995.2334. PMID 7677777.CS1 maint: Multiple names: authors list (link)
• Naruse S, Igarashi S, Furuya T; et al. (1994). "Structures of the human and mouse growth inhibitory factor-encoding genes". Gene. 144 (2): 283–7. PMID 8039715.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Moffatt P, Séguin C (1998). "Expression of the gene encoding metallothionein-3 in organs of the reproductive system". DNA Cell Biol. 17 (6): 501–10. PMID 9655243.
• Garrett SH, Sens MA, Shukla D; et al. (1999). "Metallothionein isoform 3 expression in the human prostate and cancer-derived cell lines". Prostate. 41 (3): 196–202. PMID 10517878.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Ye B, Maret W, Vallee BL (2001). "Zinc metallothionein imported into liver mitochondria modulates respiration". Proc. Natl. Acad. Sci. U.S.A. 98 (5): 2317–22. doi:10.1073/pnas.041619198. PMID 11226237.CS1 maint: Multiple names: authors list (link)
• Kim D, Garrett SH, Sens MA; et al. (2002). "Metallothionein isoform 3 and proximal tubule vectorial active transport". Kidney Int. 61 (2): 464–72. doi:10.1046/j.1523-1755.2002.00153.x. PMID 11849386.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Palumaa P, Eriste E, Njunkova O; et al. (2002). "Brain-specific metallothionein-3 has higher metal-binding capacity than ubiquitous metallothioneins and binds metals noncooperatively". Biochemistry. 41 (19): 6158–63. PMID 11994011.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Uchida Y, Gomi F, Masumizu T, Miura Y (2002). "Growth inhibitory factor prevents neurite extension and the death of cortical neurons caused by high oxygen exposure through hydroxyl radical scavenging". J. Biol. Chem. 277 (35): 32353–9. doi:10.1074/jbc.M111263200. PMID 12058024.CS1 maint: Multiple names: authors list (link)
• You HJ, Lee KJ, Jeong HG (2002). "Overexpression of human metallothionein-III prevents hydrogen peroxide-induced oxidative stress in human fibroblasts". FEBS Lett. 521 (1–3): 175–9. PMID 12067712.CS1 maint: Multiple names: authors list (link)
• Roschitzki B, Vasák M (2002). "A distinct Cu(4)-thiolate cluster of human metallothionein-3 is located in the N-terminal domain". J. Biol. Inorg. Chem. 7 (6): 611–6. doi:10.1007/s00775-002-0339-1. PMID 12072966.
• Dutta R, Sens DA, Somji S; et al. (2002). "Metallothionein isoform 3 expression inhibits cell growth and increases drug resistance of PC-3 prostate cancer cells". Prostate. 52 (2): 89–97. doi:10.1002/pros.10097. PMID 12111700.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Tate DJ, Miceli MV, Newsome DA (2002). "Expression of metallothionein isoforms in human chorioretinal complex". Curr. Eye Res. 24 (1): 12–25. PMID 12187490.CS1 maint: Multiple names: authors list (link)
• You HJ, Oh DH, Choi CY; et al. (2002). "Protective effect of metallothionein-III on DNA damage in response to reactive oxygen species". Biochim. Biophys. Acta. 1573 (1): 33–8. PMID 12383939.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Strausberg RL, Feingold EA, Grouse LH; et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)