MYOCD

Myocardin
Identifiers
Symbols	MYOCD ; MYCD
External IDs	Template:OMIM5 Template:MGI HomoloGene: 17043
Gene ontology Molecular function Template:GNF GO Template:GNF GO Cellular component Template:GNF GO Biological process Template:GNF GO Template:GNF GO
RNA expression pattern
File:PBB GE MYOCD gnf1h03126 at tn.png
More reference expression data
Orthologs
Template:GNF Ortholog box
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a

Myocardin, also known as MYOCD, is a human gene.

Myocardin is a smooth and cardiac muscle-specific transcriptional coactivator of serum response factor. When expressed ectopically in nonmuscle cells, myocardin can induce smooth muscle differentiation by its association with serum response factor (SRF; MIM 600589).[supplied by OMIM]

Further reading

• Wang D, Chang PS, Wang Z; et al. (2001). "Activation of cardiac gene expression by myocardin, a transcriptional cofactor for serum response factor". Cell. 105 (7): 851–62. PMID 11439182.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Wang DZ, Li S, Hockemeyer D; et al. (2003). "Potentiation of serum response factor activity by a family of myocardin-related transcription factors". Proc. Natl. Acad. Sci. U.S.A. 99 (23): 14855–60. doi:10.1073/pnas.222561499. PMID 12397177.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Du KL, Ip HS, Li J; et al. (2003). "Myocardin is a critical serum response factor cofactor in the transcriptional program regulating smooth muscle cell differentiation". Mol. Cell. Biol. 23 (7): 2425–37. PMID 12640126.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Wang Z, Wang DZ, Pipes GC, Olson EN (2003). "Myocardin is a master regulator of smooth muscle gene expression". Proc. Natl. Acad. Sci. U.S.A. 100 (12): 7129–34. doi:10.1073/pnas.1232341100. PMID 12756293.CS1 maint: Multiple names: authors list (link)
• Ota T, Suzuki Y, Nishikawa T; et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Du KL, Chen M, Li J; et al. (2004). "Megakaryoblastic leukemia factor-1 transduces cytoskeletal signals and induces smooth muscle cell differentiation from undifferentiated embryonic stem cells". J. Biol. Chem. 279 (17): 17578–86. doi:10.1074/jbc.M400961200. PMID 14970199.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Wang Z, Wang DZ, Hockemeyer D; et al. (2004). "Myocardin and ternary complex factors compete for SRF to control smooth muscle gene expression". Nature. 428 (6979): 185–9. doi:10.1038/nature02382. PMID 15014501.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• van Tuyn J, Knaän-Shanzer S, van de Watering MJ; et al. (2006). "Activation of cardiac and smooth muscle-specific genes in primary human cells after forced expression of human myocardin". Cardiovasc. Res. 67 (2): 245–55. doi:10.1016/j.cardiores.2005.04.013. PMID 15907818.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Liu ZP, Wang Z, Yanagisawa H, Olson EN (2005). "Phenotypic modulation of smooth muscle cells through interaction of Foxo4 and myocardin". Dev. Cell. 9 (2): 261–70. doi:10.1016/j.devcel.2005.05.017. PMID 16054032.CS1 maint: Multiple names: authors list (link)
• Doi H, Iso T, Yamazaki M; et al. (2006). "HERP1 inhibits myocardin-induced vascular smooth muscle cell differentiation by interfering with SRF binding to CArG box". Arterioscler. Thromb. Vasc. Biol. 25 (11): 2328–34. doi:10.1161/01.ATV.0000185829.47163.32. PMID 16151017.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Zody MC, Garber M, Adams DJ; et al. (2006). "DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage". Nature. 440 (7087): 1045–9. doi:10.1038/nature04689. PMID 16625196.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Chow N, Bell RD, Deane R; et al. (2007). "Serum response factor and myocardin mediate arterial hypercontractility and cerebral blood flow dysregulation in Alzheimer's phenotype". Proc. Natl. Acad. Sci. U.S.A. 104 (3): 823–8. doi:10.1073/pnas.0608251104. PMID 17215356.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Milyavsky M, Shats I, Cholostoy A; et al. (2007). "Inactivation of myocardin and p16 during malignant transformation contributes to a differentiation defect". Cancer Cell. 11 (2): 133–46. doi:10.1016/j.ccr.2006.11.022. PMID 17292825.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Li HJ, Haque Z, Lu Q; et al. (2007). "Steroid receptor coactivator 3 is a coactivator for myocardin, the regulator of smooth muscle transcription and differentiation". Proc. Natl. Acad. Sci. U.S.A. 104 (10): 4065–70. doi:10.1073/pnas.0611639104. PMID 17360478.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)
• Pijnappels DA, van Tuyn J, de Vries AA; et al. (2007). "Resynchronization of separated rat cardiomyocyte fields with genetically modified human ventricular scar fibroblasts". Circulation. 116 (18): 2018–28. doi:10.1161/CIRCULATIONAHA.107.712935. PMID 17938287.CS1 maint: Explicit use of et al. (link) CS1 maint: Multiple names: authors list (link)