Malignant peripheral nerve sheath tumor epidemiology and demographics
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Marjan Khan M.B.B.S.[2]
Overview
Malignant peripheral nerve sheath tumors comprise ∼2% of all sarcomas whichare a small fraction of a group of cancers that affect 5 people per million per year. The incidence of malignant peripheral nerve sheath tumor is approximately 0.1 per 100,000 individuals worldwide.[1] The incidence of malignant peripheral nerve sheath tumor increases with age.[1] Malignant peripheral nerve sheath tumor affects men and women equally.[2]
Incidence
- Malignant peripheral nerve sheath tumors comprise ∼2% of all sarcomas whichare a small fraction of a group of cancers that affect 5 people per million per year.
- The incidence of malignant peripheral nerve sheath tumor is approximately 0.1 per 100,000 individuals worldwide.[1]
- Malignant peripheral nerve sheath tumor may arise at any age with no gender predilection.
- Half of MPNSTs are associated with neurofibromatosis type 1 (NF1), the autosomal dominant condition that, affecting 1 in 3000 live births, represents the most common human cancer genetic predisposition syndrome.
Age
- Malignant peripheral nerve sheath tumor may arise at any age with no gender predilection and affects men and women equally .[1]
Gender
- Malignant peripheral nerve sheath tumor may arise at any age with no gender predilection and affects men and women equally.[2]
References
- ↑ 1.0 1.1 1.2 1.3 Bates JE, Peterson CR, Dhakal S, Giampoli EJ, Constine LS (2014). "Malignant peripheral nerve sheath tumors (MPNST): a SEER analysis of incidence across the age spectrum and therapeutic interventions in the pediatric population". Pediatr Blood Cancer. 61 (11): 1955–60. doi:10.1002/pbc.25149. PMID 25130403.
- ↑ 2.0 2.1 Malignant peripheral nerve sheath tumor. Radiopaedia 2015. http://radiopaedia.org/articles/malignant-peripheral-nerve-sheath-tumour