Manchester score
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Manchester score is an indicator of prognosis in small cell lung cancer.[1][2] It is calculated from a number of physical and biochemical markers.
A patient with small cell lung cancer scores one point for each of the following: -
- Serum lactate dehydrogenase exceeds the upper limit of the reference range.
- Serum sodium concentration less than 132 mmol/l.
- Serum alkaline phosphatase over one-and-a-half times the upper limit of the reference range.
- Serum bicarbonate less than 24.
- Karnofsky performance status less than 60.
- Extensive stage disease.
Prognosis
| Manchester score | Prognostic group | Two year survival (%) |
|---|---|---|
| 0-1 | Good | 16.2 |
| 2-3 | Medium | 2.5 |
| 4 or more | Poor | 0 |
References
- ↑ Cerny, T (1987). "Pretreatment prognostic factors and scoring system in 407 small-cell lung cancer patients". International Journal of Cancer. 39 (2): 146–149. Unknown parameter
|coauthors=ignored (help) - ↑ Kawahara, Masaaki (1996). "Prognostic factors and prognostic staging system for small cell lung cancer". Japanese Journal of Clinical Oncology. Oxford University Press. 27 (3): 158–165. ISSN: 0368-2811. Unknown parameter
|coauthors=ignored (help) - ↑ Maestu, I (Jun 1997). "Pretreatment prognostic factors for survival in small-cell lung cancer: a new prognostic index and validation of three known prognostic indices on 341 patients". Annals of Oncology. 8 (6): 547–553. Unknown parameter
|coauthors=ignored (help)