Melanocytic nevus historical perspective
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: : Qurrat-ul-ain Abid, M.D.[2]; Roukoz A. Karam, M.D.[3]
Overview
Dysplastic nevus was first discovered by Clark and his colleagues in 1978.
Historical Perspective
- Dysplastic nevus was first discovered by Clark and his colleagues in 1978.[1]
- The name ‘dysplastic nevus’ was proposed since they are benign melanocytic nevi that include cytologic atypia, similar to dysplastic lesions of other organs, such as the cervix.[2]
- At one time in the 1950s and 60s, (and, to lesser extent, currently) a mole was known as a “beauty mark” when it appeared in certain spots on a woman’s face. Examples include Marilyn Monroe, model Cindy Crawford and singer Madonna. Madonna's facial mole -- below her right nostril -- has been surgically removed.
References
- ↑ Clark WH, Reimer RR, Greene M, Ainsworth AM, Mastrangelo MJ (1978). "Origin of familial malignant melanomas from heritable melanocytic lesions. 'The B-K mole syndrome'". Arch Dermatol. 114 (5): 732–8. PMID 646394.
- ↑ Elder DE, Goldman LI, Goldman SC, Greene MH, Clark WH (1980). "Dysplastic nevus syndrome: a phenotypic association of sporadic cutaneous melanoma". Cancer. 46 (8): 1787–94. doi:10.1002/1097-0142(19801015)46:8<1787::aid-cncr2820460816>3.0.co;2-s. PMID 7427881.