Methemoglobinemia classification
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aksiniya Stevasarova, M.D.
Overview
Methemoglobinemia may be classified into two groups, based on the mechanism of its formation- acquired and congenital methemoglobinemia.
Classification
Methemoglobinemia may be classified into two groups, based on the mechanism of its formation- acquired and congenital methemoglobinemia.
Congenital (Hereditary) Methemoglobinemia
- There are three main congenital conditions that lead to methemoglobinemia:
1.Cytochrome b5 reductase deficiency and pyruvate kinase deficiency[1]
3.Presence of abnormal hemoglobin (Hb M)
Acquired or Acute Methemoglobinemia
- The most common causes are different oxidant drugs, toxins and chemicals.[2]
References
- ↑ Template:Haematologia (Budap). 1982 Dec;15(4):389-99. Enzymopenic hereditary methemoglobinemia. Jaffé ER. pmid=PMID: 6764628
- ↑ Template:Med Toxicol. 1986 Jul-Aug;1(4):253-60. Drug- and chemical-induced methaemoglobinaemia. Clinical features and management. Hall AH, Kulig KW, Rumack BH.pmid=PMID: 3537620