Methyl isothiocyanate
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Methyl isothiocyanate, CH3N=C=S, also known by the acronymn MITC, is a low melting (m.p. 31°C) colorless solid used in organic chemistry. It is a volatile (b.p. 117°C) lachrymator. Density 1.07 g cm–3. Its most characteristic reaction is with amines to to give methyl thioureas:
- CH3NCS + R2NH → R2NC(S)NHCH3
MITC is used in agriculture as a soil fumigant. It is generated in situ from the reaction of metam sodium with water.
See also