Middle East respiratory syndrome coronavirus infection historical perspective
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ammu Susheela, M.D. [2], João André Alves Silva, M.D. [3]
Overview
The index case of MERS-CoV infection was reported in Saudi Arabia in September, 2012. Dr. Ali Mohamed Zaki, an Egyptian virologist, was the first to attribute MERS-CoV to coronavirus.
Historical Perspective
- The index case of MERS-CoV infection was reported in Saudi Arabia in September, 2012. The index patient was a middle-aged man who presented with pneumonia and acute kidney injury.
- The virus was first termed human coronavirus-EMC (Erasmus Medical Center), then it was termed human coronavirus England 1 following the isolation of the virus from a patient in the United Kingdom who had recently traveled to the Middle East.[1][2]
- On June 13 2012, Egyptian virologist, Dr. Ali Mohamed Zaki, identified the coronavirus responsible for the syndrome in Saudi Arabia.[3]
- On September 2012, the virus was first reported outside Saudi Arabia in Qatar in a 44 year old man who had recently traveled to Saudi Arabia.
- It was later determined that viruses from the EMC/2012 and England/Qatar/2012, date to early 2011, suggesting that these cases had likely descended from a single zoonotic event.[4]
- During the 2012-2013 outbreak, the World Health Organization (WHO) International Health Regulations Emergency Committee determined that MERS-CoV did not meet the criteria for a "public health emergency of international concern", but was nevertheless of "serious and of great concern".
References
- ↑ van Boheemen S, de Graaf M, Lauber C, Bestebroer TM, Raj VS, Zaki AM; et al. (2012). "Genomic characterization of a newly discovered coronavirus associated with acute respiratory distress syndrome in humans". MBio. 3 (6). doi:10.1128/mBio.00473-12. PMC 3509437. PMID 23170002.
- ↑ Bermingham A, Chand MA, Brown CS, Aarons E, Tong C, Langrish C; et al. (2012). "Severe respiratory illness caused by a novel coronavirus, in a patient transferred to the United Kingdom from the Middle East, September 2012". Euro Surveill. 17 (40): 20290. PMID 23078800.
- ↑ Zaki AM, van Boheemen S, Bestebroer TM, Osterhaus AD, Fouchier RA (2012). "Isolation of a novel coronavirus from a man with pneumonia in Saudi Arabia". N Engl J Med. 367 (19): 1814–20. doi:10.1056/NEJMoa1211721. PMID 23075143.
- ↑ Cotten M, Lam TT, Watson SJ, Palser AL, Petrova V, Grant P; et al. (2013). "Full-genome deep sequencing and phylogenetic analysis of novel human betacoronavirus". Emerg Infect Dis. 19 (5): 736–42B. doi:10.3201/eid1905.130057. PMC 3647518. PMID 23693015.