Miosis causes

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Luke Rusowicz-Orazem, B.S.

Overview

Miosis is usually caused as a side effect from drugs intending to treat pain, as well as chemotherapy agents. Other common causes include various neurologic and ophthalmologic conditions.

Causes

Common Causes

• Acetaminophen
• Acetylcholine
• Ambenonium
• Camptothecin derivatives
• Carbachol
• Carbamates
• Chemotherapy
• Cholinergic agents
• Codeine 
• Dapiprazole
• Demerol
• Diamorphine
• Distigmine
• Donepezil toxicity
• Fentanyl
• Haloperidol
• Mao inhibitors
• Methadone
• Miostat
• Miotics
• Mirtazapine
• Morphine
• Muscarine
• Naphazoline
• Neostigmine
• Olanzapine
• Ondansetron
• Opioid poisoning 
• Organophosphates
• Oxycodone
• Oxymetazoline
• Parasympathomimetics
• Pethidine
• Phenoxybenzamine
• Physostigmine
• Pilocarpine 
• Pyridostigmine
• Quetiapine
• Tetrahydazoline
• Thorazine
• Tramadol
• Trazodone

Causes by Organ System

Cardiovascular	Cerebrovascular arteriosclerosis, Corneal ulcer
Chemical/Poisoning	Clonidine poisoning , Mustard gas, Nicotine, Phencyclidine poisoning, Tacrine toxicity
Dental	No underlying causes
Dermatologic	No underlying causes
Drug Side Effect	Acetaminophen , Acetylcholine, Ambenonium, Camptothecin derivatives, Carbachol, Carbamates, Chemotherapy, Cholinergic agents, Codeine , Dapiprazole, Demerol, Diamorphine, Distigmine, Donepezil toxicity, Fentanyl, Haloperidol, Mao inhibitors, Methadone, Miostat, Miotics, Mirtazapine, Morphine, Muscarine, Naphazoline, Neostigmine, Olanzapine, Ondansetron, Opioid poisoning , Organophosphates, Oxycodone, Oxymetazoline, Parasympathomimetics, Pethidine, Phenoxybenzamine, Physostigmine, Pilocarpine , Pyridostigmine, Quetiapine, Tetrahydazoline, Thorazine, Tramadol, Trazodone
Ear Nose Throat	No underlying causes
Endocrine	No underlying causes
Environmental	No underlying causes
Gastroenterologic	No underlying causes
Genetic	Hereditary disorders, Hereditary sensorimotor neuropathy type 3, Stormorken syndrome
Hematologic	Hyphema, Intracranial hemorrhage, Pontine hemorrhage
Iatrogenic	No underlying causes
Infectious Disease	Acute iritis, Iridocyclitis, Iritis, Tertiary syphillis, Uveitis
Musculoskeletal/Orthopedic	No underlying causes
Neurologic	Adie's pupil , Argyll robertson pupils, Cerebrovascular arteriosclerosis, Cluster headache, Coma, Fatal familial insomnia, Horner's syndrome, Intracranial hemorrhage, Lateral medullary syndrome, Migraine, Neuropathy, Raeder paratrigeminal syndrome, Stormorken syndrome, Wallenberg's syndrome
Nutritional/Metabolic	No underlying causes
Obstetric/Gynecologic	No underlying causes
Oncologic	Pancoast tumor
Ophthalmologic	Acute iritis, Adie's pupil , Anisocoria, Argyll robertson pupils, Corneal foreign body, Corneal ulcer, Horner's syndrome, Hyphema, Iridocyclitis, Iritis, Lateral medullary syndrome, Posterior iris synechiae, Raeder paratrigeminal syndrome, Uveitis
Overdose/Toxicity	Heroin
Psychiatric	No underlying causes
Pulmonary	No underlying causes
Renal/Electrolyte	No underlying causes
Rheumatology/Immunology/Allergy	Parry-romberg syndrome
Sexual	Tertiary syphillis
Trauma	No underlying causes
Urologic	No underlying causes
Miscellaneous	No underlying causes

Causes in Alphabetical Order

• Acetaminophen
• Acetylcholine
• Acute iritis
• Adie's pupil 
• Ambenonium
• Anisocoria
• Argyll robertson pupils
• Camptothecin derivatives
• Cancer chemotherapy drugs
• Carbachol
• Carbamates
• Cerebrovascular arteriosclerosis
• Chemotherapy
• Cholinergic agents
• Clonidine poisoning 
• Cluster headache
• Codeine 
• Coma
• Corneal foreign body
• Corneal ulcer
• Dapiprazole
• Demerol
• Diamorphine
• Distigmine
• Donepezil toxicity
• Fatal familial insomnia
• Fentanyl
• Haloperidol
• Hereditary disorders
• Hereditary sensorimotor neuropathy type 3
• Heroin
• Horner's syndrome
• Hyphema
• Intracranial hemorrhage
• Iridocyclitis
• Iritis
• Lateral medullary syndrome
• Mao inhibitors
• Methadone
• Migraine
• Miostat
• Miotics
• Mirtazapine
• Morphine
• Muscarine
• Mustard gas
• Naphazoline
• Neostigmine
• Neuropathy
• Nicotine
• Olanzapine
• Ondansetron
• Opioid poisoning 
• Organophosphates
• Oxycodone
• Oxymetazoline
• Pancoast tumor 
• Parasympathomimetics
• Parry-romberg syndrome
• Pethidine
• Phencyclidine poisoning
• Phenoxybenzamine
• Physostigmine
• Pilocarpine 
• Pontine hemorrhage
• Posterior iris synechiae
• Pyridostigmine
• Quetiapine
• Raeder paratrigeminal syndrome
• Stormorken syndrome
• Tacrine toxicity
• Tertiary syphillis
• Tetrahydazoline
• Thorazine
• Tramadol
• Trazodone
• Uveitis
• Wallenberg's syndrome