Molluscum contagiosum laboratory findings

Molluscum contagiosum Microchapters
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mahshid Mir, M.D. [2]

Overview

There are no diagnostic lab findings associated with molluscum contagiosum. The diagnosis of molluscum contagiosum should be made clinically. For confirmation of the diagnosis, pathological studies can be done which involve H&E staining of the infected tissue and direct visualization. it is also recommended to test for other sexually transmitted diseases in adults and for immunodeficiency related diseases.

Laboratory Findings

• Laboratory studies usually are not indicated in children with molluscum contagiosum. Sexually active adolescents and adults with genital lesions should be evaluated for the presence of other sexually transmitted diseases.
• Patients with extensive lesions should be tested for human immunodeficiency virus (HIV) infection, and the possibility of other immune system disorders should also be considered.
• Electron microscopic evaluation of tissue is not a part of routine diagnosis procedure, but if done it may show:
  • Typical brick-shaped poxvirus particles inside the infected tissue which is highly specific for diagnosis.
  • Electron microscopy can also identify infected cells that appear normal on light microscopy