Multiple cutaneous leiomyoma

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Kiran Singh, M.D. [2]

Overview

Multiple cutaneous leiomyomas, also known as Pilar leiomyomas,^[1] arise from the arrectores pilorum muscles, and are made up of a poorly circumscribed proliferation of haphazardly arranged smooth muscle fibers located in the dermis that appear to infiltrate the surrounding tissue and may extend into the subcutis.^[1]

Sometimes associated with uterine leiomyomas (a combination known as multiple cutaneous and uterine leiomyomatosis, MCUL), these lesions may also be a manifestation of the hereditary leiomyomatosis and renal cell cancer syndrome.

Diagnosis

Physical Examination

Skin

Extremity

Multiple cutaneous leiomyoma. Adapted from Dermatology Atlas.^[2]
Multiple cutaneous leiomyoma. Adapted from Dermatology Atlas.^[2]
Multiple cutaneous leiomyoma. Adapted from Dermatology Atlas.^[2]
Multiple cutaneous leiomyoma. Adapted from Dermatology Atlas.^[2]
Multiple cutaneous leiomyoma. Adapted from Dermatology Atlas.^[2]
Multiple cutaneous leiomyoma. Adapted from Dermatology Atlas.^[2]
Multiple cutaneous leiomyoma. Adapted from Dermatology Atlas.^[2]
Multiple cutaneous leiomyoma. Adapted from Dermatology Atlas.^[2]
Multiple cutaneous leiomyoma. Adapted from Dermatology Atlas.^[2]
Multiple cutaneous leiomyoma. Adapted from Dermatology Atlas.^[2]

References

↑ ^1.0 ^1.1 Freedberg, et al. (2003). Fitzpatrick's Dermatology in General Medicine. (6th ed.). Page 1033. McGraw-Hill. ISBN 0-07-138076-0.
↑ ^2.0 ^2.1 ^2.2 ^2.3 ^2.4 ^2.5 ^2.6 ^2.7 ^2.8 ^2.9 "Dermatology Atlas".

External links

"Hereditary multiple cutaneous leiomyomatosis" at Atlas of Genetics and Cytogenetics in Oncology and Haematology

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[Fitz2-1] 1.0 ^1.1 Freedberg, et al. (2003). Fitzpatrick's Dermatology in General Medicine. (6th ed.). Page 1033. McGraw-Hill. ISBN 0-07-138076-0.

[Dermatology_Atlas-2] 2.0 ^2.1 ^2.2 ^2.3 ^2.4 ^2.5 ^2.6 ^2.7 ^2.8 ^2.9 "Dermatology Atlas".

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[2]