NEURL2

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Identifiers
Aliases
External IDs	GeneCards: [1]
Orthologs
Species	Human	Mouse
Entrez	n/a	n/a
Ensembl	n/a	n/a
UniProt	n/a	n/a
RefSeq (mRNA)	n/a	n/a
RefSeq (protein)	n/a	n/a
Location (UCSC)	n/a	n/a
PubMed search	n/a	n/a
Wikidata
View/Edit Human

Neuralized-like protein 2 is a protein that in humans is encoded by the NEURL2 gene.

Function

This gene encodes a protein that is involved in the regulation of myofibril organization. This protein is likely the adaptor component of the E3 ubiquitin ligase complex in striated muscle, and it regulates the ubiquitin-mediated degradation of beta-catenin during myogenesis.

See also

• NEURL (gene)

Further reading

• Song R, Koo BK, Yoon KJ, et al. (2007). "Neuralized-2 regulates a Notch ligand in cooperation with Mind bomb-1". J. Biol. Chem. 281 (47): 36391–400. doi:10.1074/jbc.M606601200. PMID 17003037.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Nastasi T, Bongiovanni A, Campos Y, et al. (2004). "Ozz-E3, a muscle-specific ubiquitin ligase, regulates beta-catenin degradation during myogenesis". Dev. Cell. 6 (2): 269–82. doi:10.1016/S1534-5807(04)00020-6. PMID 14960280.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Deloukas P, Matthews LH, Ashurst J, et al. (2002). "The DNA sequence and comparative analysis of human chromosome 20". Nature. 414 (6866): 865–71. doi:10.1038/414865a. PMID 11780052.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.