ADP-sugar pyrophosphatase is an enzyme that in humans is encoded by the NUDT5gene.[1][2]
Nudix hydrolases, such as NUDT5, eliminate toxic nucleotide derivatives from the cell and regulate the levels of important signaling nucleotides and their metabolites (McLennan, 1999).[supplied by OMIM][2]
References
↑McLennan AG (Aug 1999). "The MutT motif family of nucleotide phosphohydrolases in man and human pathogens (review)". Int J Mol Med. 4 (1): 79–89. doi:10.3892/ijmm.4.1.79. PMID10373642.
Rush J, Moritz A, Lee KA, et al. (2005). "Immunoaffinity profiling of tyrosine phosphorylation in cancer cells". Nat. Biotechnol. 23 (1): 94–101. doi:10.1038/nbt1046. PMID15592455.
Yang H, Slupska MM, Wei YF, et al. (2000). "Cloning and characterization of a new member of the Nudix hydrolases from human and mouse". J. Biol. Chem. 275 (12): 8844–53. doi:10.1074/jbc.275.12.8844. PMID10722730.