Necrotising enterocolitis causes
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
NEC has no definitive known cause. An infectious agent has been suspected, as cluster outbreaks in neonatal intensive care units (NICUs) have been seen, but no common organism has been idenitfied. A combination of intestinal flora, inherent weakness in the neonatal immune system, alterations in mesenteric blood flow and milk feeding may be factors. NEC is almost never seen in infants before oral feedings are initiated.