Nephrocalcinosis causes
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Causes
Causes of cortical nephrocalcinosis
- Acute cortical necrosis. May be caused by:
- Chronic glomerulonephritis
- Alport syndrome
- Prolonged hypercalcemia and/or hypercalciuria
- Renal transplant rejection
- Sickle cell disease (rare)
- Vitamin B6 deficiency (pyridoxine deficiency) (rare)
Causes of medullary nephrocalcinosis
- Medullary sponge kidney
- Hyperparathyroidism
- Hypoparathyroidism
- Renal tubular acidosis (specifically distal RTA)
- Renal tuberculosis
- Renal papillary necrosis
- Hyperoxaluria
Other causes of hypercalcemia (and thus hypercalciuria)
- Immobilization (leading to hypercalcemia and hypercalciuria)
- Milk-alkali syndrome
- Hypervitaminosis D
- Sarcoidosis