Norspermidine
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Norspermidine is a homologue of spermidine. While norspermidine has been found to occur naturally in some species of plants[1][2], bacteria[3], and algae[4], it is not known to be a natural product in humans as spermidine is.
Norspermidine is being researched for its use as an antitumor medicine in cancer treatment[5][6].
References
- ↑ Rodriguez-Garay, B; et al. (1989). "Detection of Norspermidine and Norspermine in Medicago sativa L. (Alfalfa)". Plant Physiology. 89: 525–529. ISSN: 0032-0889.
- ↑ Hamana, K; et al. (1998). "Unusual polyamines in aquatic plants: the occurrence of homospermidine, norspermidine, thermospermine, norspermine, aminopropylhomospermidine, bis(aminopropyl)ethanediamine, and methylspermidine". Can. J. Bot. 76 (1): 130–133. doi:10.1139/cjb-76-1-130.
- ↑ Yamamoto, S; et al. (Apr. 27, 1979). "Occurrence of norspermidine in some species of genera Vibrio and Beneckea". Biochem Biophys Res Commun. 87 (4): 1102–1108. PMID 313792. Check date values in:
|date=(help) - ↑ Hamana, K; Matsuzaki, S (1982). "Widespread Occurrence of Norspermidine and Norspermine in Eukaryotic Algae". J. Biochem. 91 (4): 1321–1328. ISSN: 0021-924X.
- ↑ Prakash, NJ; et al. (1988). "Antitumor activity of norspermidine, a structural homologue of the natural polyamine spermidine". Anticancer Res. 8 (4): 563–568. PMID 3140710.
- ↑ Sunkara, PS; et al. (1988). "Mechanism of antitumor activity of norspermidine, a structural homologue of spermidine". Adv Exp Med Biol. 250: 707–716. PMID 3255245.