Ovarian follicle atresia
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Overview
Ovarian follicle atresia is a process which through ovarian follicles undergo a degenerative process called atresia during reproductive life, almost 99% of ovarian follicles undergo this process and only 1% proceed into ovulation.[1][2] this is a hormonally controlled apoptotic process[3] that depends dominantly depends on granulosa cell apoptosis. until now at least five cell death ligand-receptor systems tumor necrosis factor alpha(TNF alpha) and receptors, Fas ligand and receptors, TNF-related apoptosis-inducing ligand (TRAIL; also called APO-2) and receptors, APO-3 ligand and receptors, and PFG-5 ligand and receptors have been reported in granulosa cells [1]
References
- ↑ 1.0 1.1 Manabe N, Goto Y, Matsuda-Minehata F; et al. (2004). "Regulation mechanism of selective atresia in porcine follicles: regulation of granulosa cell apoptosis during atresia". J. Reprod. Dev. 50 (5): 493–514. PMID 15514456. Unknown parameter
|month=ignored (help) - ↑ Hsueh AJ, Billig H, Tsafriri A (1994). "Ovarian follicle atresia: a hormonally controlled apoptotic process". Endocr. Rev. 15 (6): 707–24. PMID 7705278. Unknown parameter
|month=ignored (help) - ↑ Kaipia A, Hsueh AJ (1997). "Regulation of ovarian follicle atresia". Annu. Rev. Physiol. 59: 349–63. doi:10.1146/annurev.physiol.59.1.349. PMID 9074768.